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RTOG 0324 Protocol Information

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A Phase II Study of Cetuximab (C225) In Combination with Chemoradiation in Patients with Stage IIIA/B Non-Small Cell Lung Cancer (NSCLC)
Protocol Documents
Current Version Date: 5/6/2010
Principal Investigator: George Blumenschein, M.D.
Primary Objective:

Determine the feasibility of concurrent cetuximab and chemoradiation as measured by safety and compliance. Safety is measured by the rate of grade 3 or worse nonhematological toxicities occurring prior to the beginning of consolidation therapy (including

Patient Population:

Histologically or cytologically documented NSCLC; Patients must be MO. Patients with T1-T2 with N2 or T3N1-2 are eligible, if inoperable. Patients withT4 with any N or any T with N2 or N3 disease are eligible if unresectable.

Target Accrual: 84
Current Accrual: 93
Status: Closed to Accrual
Date: 6/3/2005
Participating Sites:
Allegiance Health/W.A. Foote Memorial Hospital Jackson MI
Christiana Care Health Services, Inc. CCOP Newark DE
Forsyth Regional Medical Center Winston Salem NC
Greenville CCOP - Cancer Centers of the Carolinas-Eastside Greenville SC
Hematology-Oncology Associates of CNY CCOP East Syracuse NY
Hurley Cancer Center Flint MI
Mercy Hospital Port Huron Port Huron MI
Methodist Cancer Center Omaha NE
Michigan Cancer Research Consortium CCOP Ann Arbor MI
Oakwood Healthcare Inc Dearborn MI
Saint Alphonsus Regional Medical Center Boise ID
Sparrow Regional Cancer Center Lansing MI
St Francis Hospital & Medical Center Hartford CT
St. Johns Hospital & Medical Center Grosse Pointe Woods MI
St. Joseph Mercy Hospital Ann Arbor MI
St. Joseph Mercy Oakland Pontac MI
St. Mary Mercy Hospital Livonia MI
St. Mary`s Medical Center Saginaw MI
Tallahassee Memorial Hospital Tallahassee FL
University of Texas-MD Anderson Cancer Center Houston TX
Webber Cancer Center Warren MI
Yale-New Haven Hospital Saint Raphael Campus New Haven CT
Updated: 11/6/2012

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