NSABP B-39: A Randomized Phase III Study of Conventional Whole Breast Irradiation (WBI) versus Partial Breast Irradiation (PBI) for Women with Stage 0, I, or II Breast Cancer
Principal Investigator: Frank Vicini, MD & Julia White, MD
Primary Objective: To determine whether partial breast irradiation (PBI) limited to the region of the tumor bed following lumpectomy provides equivalent local tumor control in the breast compared to conventional whole breast irradiation (WBI) in the local management of early stage breast cancer.
Patient Population: Patients with stage 0 (DCIS) or stage I or II invasive adenocarcinoma of the breast with no evidence of metastatic disease. If stage II, tumor size must be 3 cm or less.
Protocol available on CTSU website at www.ctsu.org
Target Accrual: 4300
Current Accrual: 2053
Status: Closed to Accrual
Date: 4/16/2013
Participating Sites:
| Arizona Center for Cancer Care |
Peoria |
AZ |
| Arizona Oncology Services Foundation |
Scottsdale |
AZ |
| Cleveland Clinic Wooster Specialty Center |
Wooster |
OH |
| Columbia-Saint Mary's Milwaukee |
Milwaukee |
WI |
| Innovative Healthcare Research Consortium |
Glendale |
CA |
| IU Health Central Indiana Cancer Centers |
Indianapolis |
IN |
| Memorial Sloan Kettering Cancer Center (MSKCC) at Phelps |
Sleepy Hollow |
NY |
| University of Kansas Cancer Center-North |
Kansas City |
MO |
| University of Texas Southwestern Medical School |
Dallas |
TX |
| USON- Texas Oncology-Denton |
Denton |
TX |
| USON-Texas Oncology- Sherman |
Sherman |
TX |
| USON-Williamette Valley Cancer Center |
Eugene |
OR |
Updated: 4/16/2013