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RTOG 0529 Protocol Information

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A Phase II Evaluation of Dose-Painted IMRT in Combination with 5-Fluorouracil and Mitomycin-C for Reduction of Acute Morbidity in Carcinoma of the Anal Canal
Protocol Documents
Current Version Date: 8/17/2011
Principal Investigator: Lisa Kachnic, MD
Primary Objective:

To determine if the combined rate of >= grade 2 GI and GU adverse events from IMRT+ 5-FU & Mitomycin-C is decreased by at least 15% in the first 90 days following the start of treatment, as compared to the RT+ 5-FU & Mitomycin-C arm from RTOG 9811

Patient Population:

Histologically-proven, invasive primary squamous, basaloid, or cloacogenic carcinoma of the anal canal; T stage 2-4 and N0-N3 stage

Target Accrual: 59
Current Accrual: 63
Status: Closed to Accrual
Date:
Participating Sites:
ACR Clinical Research Center Philadelphia PA
Akron City Hospital Akron OH
Akron General Medical Center Akron OH
Albert Einstein Medical Center Philadelphia PA
Allegiance Health/W.A. Foote Memorial Hospital Jackson MI
Aria Health Philadelphia PA
Atrium Medical Center-Middletown Regional Hospital Franklin OH
Auburn Radiation Oncology Center Auburn CA
Baptist Hospital of Miami Miami FL
Barnes Jewish West County Hospital St. Louis MO
Bay Area Medical Center Marinette WI
Bay Medical Center Panama City FL
Blanchard Valley Regional Health Center Findlay OH
Boca Raton Community Hospital-Lynn Regional Cancer Center Boca Raton FL
Borgess Medical Center Kalamazoo MI
Boston Medical Center MBCCOP Boston MA
Bronson Methodist Hospital Kalamazoo MI
Bryn Mawr Hospital Bryn Mawr PA
Cancer Care Center, Inc Salem OH
Cancer Research for the Ozarks CCOP Springfield MO
Cancer Treatment Center Wooster OH
Centre Hospitalier de l`Université de Montréal-Notre Dame Montreal Quebec
Cheshire Medical Center Keene NH
Christiana Care Health Services, Inc. CCOP Newark DE
City of Hope Medical Center Duarte CA
Community Cancer Center Normal IL
Cooper Health System Camden NJ
Cooper Health System-Voorhees Voorhees NJ
Cox Health System Springfield MO
Dartmouth Hitchcock Medical Center Lebanon NH
Dayton CCOP Kettering OH
Delaware County Memorial Hospital Drexel Hill PA
Department of Veterans Affairs Dayton OH
Dixie Medical Cancer Center East St. George UT
Evergreen Radiation Oncology Kirkland WA
Florida Radiation Oncology Group - Baptist Regional Jacksonville FL
Fox Chase Cancer Center Philadelphia PA
Fox Chase Virtua Health Cancer Treatment Center Voorhees NJ
Franciscan St. Francis Health-Beech Grove Beech Grove IN
Genesys Regional Medical Center Flint MI
Good Samaritan Hospital Dayton OH
Grandview Hospital & Medical Center Dayton OH
Green Bay Oncology at St. Vincent Hospital Green Bay WI
Greene Memorial Hospital Xenia OH
Harrison Memorial Hospital Bremerton WA
Hematology-Oncology Associates of CNY CCOP East Syracuse NY
Highland Hospital Rochester NY
Holy Cross Hospital Inc. Fort Lauderdale FL
Hurley Cancer Center Flint MI
ICON – Baptist Medical Center South Jacksonville FL
ICON – Cancer Center of Putnam Palatka FL
ICON – Flagler Cancer Center St Augustine FL
ICON – Florida Cancer Center - Beaches Jacksonville Beach FL
ICON – Orange Park Cancer Center Orange Park FL
ICON – Southside Cancer Center Jacksonville FL
Illinois Oncology Research Association CCOP Peoria IL
Image-Guided Therapy QA Center (ITC) St. Louis MO
Indiana University Health Methodist Hospital Indianapolis IN
Intermountain Medical Center Murray UT
IU Health Central Indiana Cancer Centers Indianapolis IN
Jupiter Medical Center Jupiter FL
Kalamazoo CCOP-West Michigan Cancer Center Kalamazoo MI
Kansas City CCOP Prairie Village KS
Kettering Medical Center Dayton OH
Lankenau Hospital Wynnewood PA
LDS Hospital Salt Lake City UT
Liberty Hospital Liberty MO
Logan Regional Hospital Logan UT
London Regional Cancer Program London Ontario
Loyola University Chicago Maywood IL
Main Line CCOP Wynnewood PA
Marshall Radiation Oncology Center Cameron Park CA
Mayo Clinic Rochester MN
McKay-Dee Hospital Ogden UT
Medical College of Wisconsin Milwaukee WI
Mercy General Radiation Oncology Center Sacramento CA
Mercy Hospital Port Huron Port Huron MI
Mercy San Juan Radiation Oncology Center Carmichael CA
Mercy-Springfield Springfield MO
Methodist Hospital Philadelphia PA
Methodist Medical Center of Illinois Peoria IL
Miami Valley Hospital Dayton OH
Michigan Cancer Research Consortium CCOP Ann Arbor MI
Monmouth Medical Center Long Branch NJ
Mount Sinai Comprehensive Cancer Center CCOP Miami Beach FL
Nevada Cancer Research Foundation CCOP Las Vegas NV
New Mexico Oncology Hematology Consultants, Ltd. Albuquerque NM
Norris Cotton Cancer Center Saint Johnsbury VT
Northeast Radiation Oncology Center Dunmore PA
Northwest Community Hospital Arlington Heights IL
Northwestern Memorial Hospital Chicago IL
Oakwood Healthcare Inc Dearborn MI
OSF Saint Francis Medical Center Radiation Oncology Peoria IL
Paoli Memorial Hospital Paoli PA
Pekin Cancer Treatment Center Pekin IL
Penrose Cancer Center, Penrose-St. Francis Health Services Colorado Springs CO
Piedmont Hospital Atlanta GA
Presbyterian Hospital Charlotte NC
Providence St. Joseph Medical Center - Disney Family CA Ctr Burbank CA
Radiological Associates of Sacramento Sacramento CA
Radiological Physics Center (RPC) Houston TX
Rapid City Regional Hospital Rapid City SD
Reading Hospital Reading PA
Reid Hospital & Health Care Services Richmond IN
Roseville Radiation Oncology Center Roseville CA
Roswell Park Cancer Institute Buffalo NY
Saint Alphonsus Regional Medical Center Boise ID
Saint Francis Medical Center Peoria IL
Sandra L. Maxwell Cancer Center Cedar City UT
Siteman Cancer Center/Barnes Jewish St. Peters Hospital St. Peters MO
Solano Radiation Oncology Center Vacaville CA
South Jersey Hospital Systems Vineland NJ
Southwest Virginia Regional Cancer Center Norton VA
Sparrow Regional Cancer Center Lansing MI
Sparta Cancer Center Sparta NJ
St Francis Hospital & Medical Center Hartford CT
St Johns Hospital, Cancer Institute Springfield IL
St. Francis Hospital Federal Way WA
St. Johns Hospital & Medical Center Grosse Pointe Woods MI
St. Joseph Mercy Hospital Ann Arbor MI
St. Joseph Mercy Oakland Pontac MI
St. Lukes Hospital Bethlehem PA
St. Mary Mercy Hospital Livonia MI
St. Mary`s Medical Center Saginaw MI
St. Mary's Hospital Medical Center Green Bay WI
St. Vincent Anderson Regional Hospital, Inc. Anderson IN
St. Vincent Hospital and Health Care Centers, Inc. Indianapolis IN
St. Vincent Regional Cancer Center CCOP Green Bay WI
Summa Health System Barberton Hospital Barberton OH
The Reverend Roger Patrick Dorcy Cancer Center Pueblo CO
The Schiffler Cancer Center Wheeling WV
Thomas Jefferson University Hospital Philadelphia PA
Tom Baker Cancer Centre Calgary, Alberta
University of Cincinnati Cincinnati OH
University of Colorado Denver Aurora CO
University of Kansas Cancer Center - Southwest Overland Park KS
University of Kansas Cancer Center-South Kansas City MO
University of Maryland Medical Systems Baltimore MD
University of Michigan Medical Center Ann Arbor MI
University of Rochester Rochester NY
University of Southern California Los Angeles CA
University of Utah Health Science Center Salt Lake City UT
University Pointe-Precision Radiotherapy West Chester OH
Upper Delaware Valley Cancer Center Milford PA
Upper Valley Medical Center Troy OH
USON- Texas Oncology-Sugar Land Sugarland TX
USON-Arizona Radiation Oncology Tucson AZ
USON-Fort Worth Fort Worth TX
USON-Texas Cancer Center - Dallas Southwest Dallas TX
USON-Texas Oncology- Medical City Dallas Dallas TX
USON-Texas Oncology- Sherman Sherman TX
USON-Williamette Valley Cancer Center Eugene OR
Utah Cancer Specialists Salt Lake City UT
Utah Valley Regional Medical Center Provo UT
Virginia Mason CCOP Seattle WA
Virtua-Memorial Hospital Burlington County, Inc. Mount Holly NJ
Washington University St. Louis MO
Wayne Memorial Hospital Goldsboro NC
Wayne Radiation Oncology Goldsboro NC
Wayne State University-Karmanos Cancer Institute Detroit MI
Webber Cancer Center Warren MI
Wellmont Holston Valley Medical Center Kingsport TN
Wilmed Radiation Oncology Services Wilson NC
Updated: 8/25/2011

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