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RTOG 0529 Protocol Information

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A Phase II Evaluation of Dose-Painted IMRT in Combination with 5-Fluorouracil and Mitomycin-C for Reduction of Acute Morbidity in Carcinoma of the Anal Canal
Protocol Documents
Current Version Date: 8/17/2011
Principal Investigator: Lisa Kachnic, MD
Primary Objective:

To determine if the combined rate of >= grade 2 GI and GU adverse events from IMRT+ 5-FU & Mitomycin-C is decreased by at least 15% in the first 90 days following the start of treatment, as compared to the RT+ 5-FU & Mitomycin-C arm from RTOG 9811

Patient Population:

Histologically-proven, invasive primary squamous, basaloid, or cloacogenic carcinoma of the anal canal; T stage 2-4 and N0-N3 stage

Target Accrual: 59
Current Accrual: 63
Status: Closed to Accrual
Date:
Participating Sites:
Akron City Hospital Akron OH
Auburn Radiation Oncology Center Auburn CA
Baptist Hospital of Miami Miami FL
Barnes Jewish West County Hospital St. Louis MO
Bay Area Medical Center Marinette WI
Community Cancer Center Normal IL
Cooper Health System Camden NJ
Cooper Health System-Voorhees Voorhees NJ
Dartmouth Hitchcock Medical Center Lebanon NH
Florida Radiation Oncology Group - Baptist Regional Jacksonville FL
Fox Chase Cancer Center Philadelphia PA
Fox Chase Virtua Health Cancer Treatment Center Voorhees NJ
Genesys Regional Medical Center Flint MI
Highland Hospital Rochester NY
Hurley Cancer Center Flint MI
ICON – Baptist Medical Center South Jacksonville FL
ICON – Cancer Center of Putnam Palatka FL
ICON – Flagler Cancer Center St Augustine FL
ICON – Florida Cancer Center - Beaches Jacksonville Beach FL
ICON – Orange Park Cancer Center Orange Park FL
ICON – Southside Cancer Center Jacksonville FL
Illinois Oncology Research Association CCOP Peoria IL
Marshall Radiation Oncology Center Cameron Park CA
Medical College of Wisconsin Milwaukee WI
Mercy General Radiation Oncology Center Sacramento CA
Mercy Hospital Port Huron Port Huron MI
Mercy San Juan Radiation Oncology Center Carmichael CA
Michigan Cancer Research Consortium CCOP Ann Arbor MI
Norris Cotton Cancer Center Saint Johnsbury VT
Oakwood Healthcare Inc Dearborn MI
OSF Saint Francis Medical Center Radiation Oncology Peoria IL
Pekin Cancer Treatment Center Pekin IL
Radiological Associates of Sacramento Sacramento CA
Rapid City Regional Hospital Rapid City SD
Reading Hospital Reading PA
Roseville Radiation Oncology Center Roseville CA
Saint Alphonsus Regional Medical Center Boise ID
Saint Francis Medical Center Peoria IL
Siteman Cancer Center/Barnes Jewish St. Peters Hospital St. Peters MO
Solano Radiation Oncology Center Vacaville CA
Sparrow Regional Cancer Center Lansing MI
Sparta Cancer Center Sparta NJ
St Francis Hospital & Medical Center Hartford CT
St. Johns Hospital & Medical Center Grosse Pointe Woods MI
St. Joseph Mercy Hospital Ann Arbor MI
St. Joseph Mercy Oakland Pontac MI
St. Mary Mercy Hospital Livonia MI
St. Mary`s Medical Center Saginaw MI
St. Mary's Hospital Medical Center Green Bay WI
St. Vincent Regional Cancer Center CCOP Green Bay WI
Summa Health System Barberton Hospital Barberton OH
Thomas Jefferson University Hospital Philadelphia PA
Tom Baker Cancer Centre Calgary, Alberta
University of Cincinnati Cincinnati OH
University of Colorado Denver Aurora CO
University of Rochester Rochester NY
University of Utah Health Science Center Salt Lake City UT
University Pointe-Precision Radiotherapy West Chester OH
Upper Delaware Valley Cancer Center Milford PA
Virtua-Memorial Hospital Burlington County, Inc. Mount Holly NJ
Washington University St. Louis MO
Webber Cancer Center Warren MI
Updated: 8/25/2011

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