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RTOG 0534 Protocol Information

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A Phase III Trial of Short Term Androgen Deprivation With Pelvic Lymph Node or Prostate Bed Only Radiotherapy (SPPORT) in Prostate Cancer Patients With a Rising PSA After Radical Prostatectomy
Principal Investigator: Alan Pollack, MD, PhD
Primary Objective:

To determine whether the addition of NC-STAD to PBRT improves freedom from progression (FFP) [maintenance of a PSA less than the nadir+2 ng/mL, absence of clinical failure and absence of death from any cause] for 5 years, over that of PBRT alone in men treated with salvage RT after radical prostatectomy;
To determine whether NC-STAD+PLNRT+PBRT improves FFP over that of NC-STAD+PBRT and PBRT alone in men treated with salvage RT after radical prostatectomy.

Patient Population:

Lymph node negative adenocarcinoma of the prostate treated with radical prostatectomy. Post-radical prostatectomy PSA of > = 0.1 - < 2.0 ng/mL; pathologic T3N0/Nx disease or pathologic T2N0/Nx disease, with or without a positive prostatectomy surgical margin; Gleason < = 9

Target Accrual: 1764
Current Accrual: 1565
Status: Open to Accrual
Date:
Participating Sites:
21st Century Oncology Las Vegas NV
Abbott Northwestern Hospital Minneapolis MN
Adams Cancer Center Gettysburg PA
Adena Regional Medical Center Chillicothe OH
Akron City Hospital Akron OH
Akron General Medical Center Akron OH
Allan Blair Cancer Centre Regina, SK
Alta Bates Hospital Comprehensive Cancer Center Berkeley CA
Anderson Memorial Hospital Anderson SC
Annie Penn Memorial Hospital Reidsville NC
Arizona Center for Cancer Care Peoria AZ
Arizona Oncology - Deer Valley Center Phoenix AZ
Arizona Oncology Services Foundation Scottsdale AZ
Auburn Radiation Oncology Center Auburn CA
Aultman Hospital Canton OH
Beaumont CCOP Royal Oak MI
Bellin Memorial Hospital, Inc. Green Bay WI
Beth Israel Deaconess Medical Center Boston MA
Bixby Medical Center Adrian MI
Boston Medical Center MBCCOP Boston MA
Botsford Hospital Farmington Hills MI
Brigham and Women's Hospital/Dana Farber Cancer Institute Boston MA
Brooke Army Medical Center Fort Sam Houston TX
California Pacific Medical Center San Francisco CA
Cancer Care Center, Inc Salem OH
Cancer Centers of the Carolinas-Andrews Greenville SC
Cancer Centers of the Carolinas-Faris Road Greenville SC
Cancer Centers of the Carolinas-Greer Radiation Oncology Greer SC
Cancer Centers of the Carolinas-Seneca Seneca SC
Cancer Centers of the Carolinas-Spartanburg Spartanburg SC
Cancer Treatment Center Wooster OH
Cape Cod Hospital Hyannis MA
Cape Radiation Oncology Cape Girardeau MO
Capital Health Medical Center-Hopewell Pennington NJ
Carolinas Medical Center/Levine Cancer Institute Charlotte NC
Center for Cancer Care @ Goshen Health System Goshen IN
Center for Cancer Care at Exeter Hospital Exeter NH
CentraCare Health System/Coborn Cancer Center St. Cloud MN
Central Maryland Oncology at Howard County Hospital Columbia MD
Centre Hospitalier de l`Université de Montréal-Notre Dame Montreal Quebec
Christiana Care Health Services, Inc. CCOP Newark DE
Coastal Carolina Radiation Oncology Center Wilmington NC
Columbia St. Mary's Hospital Ozaukee, Inc Mequon WI
Columbia-Presbyterian Medical Center New York NY
Columbia-Saint Mary's Milwaukee Milwaukee WI
Columbus Community Clinical Oncology Program Columbus OH
Community Memorial Hospital Menomonee Falls WI
Comprehensive Cancer Centers of Nevada - Central Valley Las Vegas NV
Comprehensive Cancer Ctrs of Nevada - Henderson Henderson NV
Comprehensive Cancer Ctrs of Nevada - Northwest Las Vegas NV
Comprehensive Cancer Ctrs of Nevada - Summerlin Las Vegas NV
Comprehensive Cancer Ctrs of Nevada - Sunset Las Vegas NV
Cone Health Cancer Center Greensboro NC
Cooper Health System Camden NJ
Cooper Health System-Voorhees Voorhees NJ
Cox Health System Springfield MO
D.N. Greenwald Mukwonago WI
Dana Farber/Brigham & Woman's CC at Milford Regional Milford MA
Dana Farber/Brigham & Women's Center at South Shore South Weymouth MA
Dartmouth Hitchcock Medical Center Lebanon NH
Dixie Medical Cancer Center East St. George UT
Doctor's Hospital Columbus OH
Dr. H. Bliss Murphy Cancer Centre St. John's, NL
Dubs Cancer Center @ Rogue Valley Medical Center Medford OR
Edward Hines, Jr. VA Hospital Hines IL
Emory University Atlanta GA
Emory University Hospital Midtown Atlanta GA
Fairview Ridges Hospital Burnsville MN
Fairview Southdale Hospital Edina MN
Florida Radiation Oncology Group - Baptist Regional Jacksonville FL
Flower Hospital Sylvania OH
Fox Chase Cancer Center Philadelphia PA
Fox Chase Virtua Health Cancer Treatment Center Voorhees NJ
Freeman Health System Joplin MO
Freeport Memorial Hospital/Ferguson Cancer Center Freeport IL
Genesis Healthcare System Zainesville OH
Genesys Regional Medical Center Flint MI
Gibbs Cancer Center-Pelham Greer SC
Grady Memorial Hospital Delaware OH
Grant Medical Center Columbus OH
Greater Baltimore Medical Center Baltimore MD
Greenville CCOP - Cancer Centers of the Carolinas-Eastside Greenville SC
Hennepin County Medical Center Minneapolis MN
Henry Ford Hospital Detroit MI
Highland Hospital Rochester NY
Holy Cross Hospital Inc. Fort Lauderdale FL
Hospital Maisonneuve-Rosemont Montreal, Quebec
Hudson Valley Oncology Associates Poughkeepsie NY
Hurley Cancer Center Flint MI
ICON – Baptist Medical Center South Jacksonville FL
ICON – Cancer Center of Putnam Palatka FL
ICON – Flagler Cancer Center St Augustine FL
ICON – Florida Cancer Center - Beaches Jacksonville Beach FL
ICON – Orange Park Cancer Center Orange Park FL
ICON – Southside Cancer Center Jacksonville FL
Indiana University Medical Center Indianapolis IN
Ingalls Memorial Hospital Harvey IL
Intermountain Medical Center Murray UT
James A. Haley Veteran's Hospital Tampa FL
James Graham Brown Cancer Ctr at University of Louisville Louisville KY
John H. Stroger, Jr. Hospital of Cook County MBCCOP Chicago IL
Jupiter Medical Center Jupiter FL
Kaiser Permanent Northern California-Rancho Cordova Rancho Cordova CA
Kaiser Permanente Northern California Santa Clara CA
Kaiser Permanente Northern California-Oakland Oakland CA
Kaiser Permanente Northern California-Rohnert Park Rohnert Park CA
Kaiser Permanente Northern California-Roseville Roseville CA
Kaiser Permanente Northern California-South Sacramento Sacramento CA
Kaiser Permanente Northern California-South San Francisco South San Francisco CA
Kalamazoo CCOP-West Michigan Cancer Center Kalamazoo MI
LAC + USC Medical Center Los Angeles CA
Lake/University Seidman Cancer Center Mentor OH
LDS Hospital Salt Lake City UT
Legacy Good Samaritan Hospital & Medical Center Portland OR
Legacy Mount Hood Medical Center Gresham OR
Legacy Salmon Creek Hospital Vancouver WA
Lewis Cancer & Research Pavilion at St. Joseph's/Candler Savannah GA
Lewis Cancer & Research Pavilion-Hilton Head/Blufton Hilton Head Island SC
Licking Memorial Hospital Newark OH
Lima Memorial Hospital Lima OH
Logan Regional Hospital Logan UT
Long Island Jewish Hospital Lake Success NY
Lowell General Hospital Cancer Center Lowell MA
Loyola University Chicago Maywood IL
Maplewood Cancer Center Maplewood MN
Marietta Memorial Hospital Marietta OH
Marin General Hospital Greenbrae CA
Marshall Radiation Oncology Center Cameron Park CA
Massachusetts General Hospital Boston MA
Mayo Clinic Rochester MN
Mayo Clinic Health System-Franciscan Healthcare LaCrosse WI
McKay-Dee Hospital Ogden UT
McLaren Cancer Institute - Flint Flint MI
McLaren Cancer Institute - Lapeer Lapeer MI
McLaren Cancer Institute - Owosso Owosso MI
McMaster Univ, Juravinski Can Ctr, Hamilton Health Sciences Hamilton, Ontario
Medical College of Wisconsin Milwaukee WI
Medical University of Ohio Toledo OH
Medical University of South Carolina Charleston SC
Memorial Sloan Kettering Cancer Center (MSKCC) at Phelps Sleepy Hollow NY
Memorial Sloan Kettering of Rockville Center Rockville NY
Memorial Sloan Kettering-Basking Ridge Basking Ridge NJ
Memorial Sloan-Kettering Cancer Center New York NY
Memorial Sloan-Kettering Cancer Center at Commack Commack NY
Mercy Cancer Center at St. Ann Toledo OH
Mercy General Radiation Oncology Center Sacramento CA
Mercy Hospital Coon Rapids MN
Mercy Hospital Port Huron Port Huron MI
Mercy Hospital St. Louis St Louis MO
Mercy Hospital-Joplin Joplin MO
Mercy San Juan Radiation Oncology Center Carmichael CA
Mercy-Springfield Springfield MO
Methodist Cancer Center Omaha NE
Metro-MN CCOP St. Louis Park MN
Michigan Cancer Research Consortium CCOP Ann Arbor MI
Mid Ohio Oncology Hematology Inc- Mark H. Zangmeister Ctr Cols OH
Mills-Peninsula Health Services San Mateo CA
Mount Carmel Medical Center-State Street Columbus OH
Mount Carmel-St. Ann's Cancer Center Westerville OH
Mount Sinai Comprehensive Cancer Center CCOP Miami Beach FL
Naval Medical Center-Portsmouth Portsmouth VA
Nevada Cancer Research Foundation CCOP Las Vegas NV
New Hanover Regional Medical Center Wilmington NC
New York Methodist Hospital Brooklyn NY
North Memorial Medical Center Robbinsdale MN
Northeast Georgia Medical Center Gainesville GA
Northside Hospital Cancer Center Atlanta GA
Northside Hospital Forsyth Cumming GA
Northwestern Ontario Regional Cancer Centre Thunder Bay, Ontario
Oakwood Healthcare Inc Dearborn MI
Ochsner Clinic CCOP New Orleans LA
Oconomowoc Memorial Hospital - ProHealth Care Inc. Oconomowoc WI
Oncology and Hematology Associates of Southwest Virginia Roanoke VA
Pacific Cancer Institute Wailuku HI
Pamela Youde Nethersole Eastern Hospital Chai Wan
Parkridge University Radiation Oncology Rochester NY
Parkview Cancer Center - Parkview Hospital Fort Wayne IN
Phelps County Regional Medical Center Rolla MO
Piedmont Fayette Hospital Fayetteville GA
Piedmont Hospital Atlanta GA
Pomona Valley Hospital Medical Center Pomona CA
Rabin Medical Center-Davidoff Cancer Center Petah Tikva
Radiation Oncology Associates Fort Wayne IN
Radiation Oncology Centers of Las Vegas Las Vegas NV
Radiological Associates of Sacramento Sacramento CA
Randolph Hospital Ashboro NC
Rapid City Regional Hospital Rapid City SD
Reading Hospital Reading PA
Regions Radiation Therapy St. Paul MN
Rice Memorial Hospital Willmar MN
Rideout Cancer Center Marysville CA
Ridgeview Medical Center Waconia MN
Riverside Methodist Hospital Columbus OH
Robinson Radiation Oncology Ravenna OH
Rockingham Memorial Hospital Hahn Cancer Center Harrisonburg VA
Roper St. Francis Hospital Charleston SC
Roseville Radiation Oncology Center Roseville CA
Roswell Park Cancer Institute Buffalo NY
Rutgers, The State University of New Jersey New Brunswick NJ
Saint Alphonsus Regional Medical Center Boise ID
Saint Elizabeth Regional Medical Center Lincoln NE
Saint John Regional Hospital Saint John, NB
Saint John's Hospital - HealthEast Maplewood MN
Saint Vincent Mercy Medical Center Toledo OH
Salem Hospital Salem OR
Sands Cancer Center Canandaigua NY
Saskatoon Cancer Centre Saskatoon, Saskatchew
Seattle Cancer Care Alliance Seattle WA
Seidman Cancer Center – Firelands Regional Medical Center Sandusky OH
Sentara Cancer Institute at Sentara CarePlex Hospital Hampton VA
Sentara Norfolk General Hospital Norfolk VA
Sentara Virginia Beach General Hospital Virginia Beach VA
Skagit Valley Hospital Mount Vernon WA
Solano Radiation Oncology Center Vacaville CA
South Atlantic Radiation Oncology Supply NC
Southern Ohio Medical Center - Cancer Center Portsmouth OH
Southside Hospital Bayshore NY
Southwest Virginia Regional Cancer Center Norton VA
Sparrow Regional Cancer Center Lansing MI
Sparta Cancer Center Sparta NJ
Spartanburg Regional Medical Center Spartanburg SC
Springfield Regional Medical Center Springfield OH
St Anne's Hospital Fall River MA
St Francis Hospital & Medical Center Hartford CT
St Francis Regional Med Cntr Wichita KS
St Johns Hospital, Cancer Institute Springfield IL
St Luke's-Roosevelt Hospital Center New York NY
St Mary's Hospital & Medical Center Grand Junction CO
St Peter's Cancer Care Center Albany NY
St. Charles Mercy Hospital Oregon OH
St. Francis Hospital Federal Way WA
St. Johns Hospital & Medical Center Grosse Pointe Woods MI
St. Joseph Mercy Hospital Ann Arbor MI
St. Joseph Mercy Oakland Pontac MI
St. Lukes Hospital Bethlehem PA
St. Lukes Hospital Association of Duluth Duluth MN
St. Luke's Medical Center Milwaukee WI
St. Mary Mercy Hospital Livonia MI
St. Mary`s Medical Center Saginaw MI
Summa Health Center at Lake Medina Medina OH
Summa Health System Barberton Hospital Barberton OH
Sutter Health Western Division Cancer Research Group Novato CA
Sutter Solano Medical Center Vallejo CA
Tate Cancer Center - North Arundel Hospital Glen Burnie MD
Tel-Aviv Sourasky Medical Center Tel-Aviv
Texas Oncology - Austin Midtown Austin TX
Texas Oncology - Central South Austin Austin TX
Texas Oncology - Round Rock Cancer Center Round Rock TX
Texas Oncology - Seton Williamson Round Rock TX
Texas Oncology - South Austin Austin TX
The Cancer Center of Hawaii-Leeward Ewa Beach HI
The Cancer Center of Hawaii-Liliha Honolulu HI
The Hospital of Central Connecticut New Britain CT
The Kirklin Clinic at Acton Road Birmingham AL
The Queen's Medical Center Honolulu HI
The Regional Cancer Center at Singing River Hospital System Pascagoula MS
Toledo Clinic Cancer Centers - Adrian Adrian MI
Toledo Clinic Cancer Centers - Maumee Maumee OH
Toledo Community Hospital Oncology Program CCOP Toledo OH
Tom Baker Cancer Centre Calgary, Alberta
Tulane University Medical Center New Orleans LA
UCSD – University of California, San Diego LaJolla CA
UH Seidman Cancer Center at Southwest General Middleburgh OH
UHHS - Chagrin Highlands Orange Village OH
UHHS - Westlake Medical Center Westlake OH
United Hospital St. Paul MN
Unity Hospital Fridley MN
Univ. of Miami Sylvester Comp Cancer Ctr-Deerfield Beach Deerfield Beach FL
University Hospitals of Cleveland Cleveland OH
University of Alabama at Birmingham Medical Center Birmingham AL
University of California Davis Medical Center Sacramento CA
University of Chicago Chicago IL
University of Colorado Denver Aurora CO
University of Florida Health Science Center Jacksonville FL
University of Hawaii Cancer Research Center MBCCOP Honolulu HI
University of Kentucky Hospital Lexington KY
University of Maryland Medical Systems Baltimore MD
University of Miami Miller School of Medicine Miami FL
University of Michigan Medical Center Ann Arbor MI
University of Mississippi Medical Center Jackson MS
University of Nebraska Medical Center Omaha NE
University of Oklahoma Health Sciences Center Oklahoma City OK
University of Rochester Rochester NY
University of Southern California Los Angeles CA
University of Texas at San Antonio San Antonio TX
University of Texas Medical Branch Galveston TX
University of Utah Health Science Center Salt Lake City UT
University of Vermont Burlington VT
University of Washington Medical Center Seattle WA
Upper Delaware Valley Cancer Center Milford PA
Upstate Carolina CCOP - Gibbs Regional Cancer Center Spartanburg SC
USON- Texas Oncology Longview Cancer Center Longview TX
USON- Texas Oncology-Denton Denton TX
USON- Texas Oncology-PA Bedford Bedford TX
USON- Texas Oncology-Sugar Land Sugarland TX
USON- Texas Oncology-Tyler Tyler TX
USON-Arizona Radiation Oncology Tucson AZ
USON-Cancer Care Northwest - Spokane Spokane WA
USON-Cancer Care Northwest-East Holland Spokane WA
USON-Fort Worth Fort Worth TX
USON-Plano West Cancer Center Plano TX
USON-Texas Oncology - Houston Memorial City Houston TX
USON-Texas Oncology- Sherman Sherman TX
USON-Texas Oncology-Lewisville Flower Mound TX
USON-Williamette Valley Cancer Center Eugene OR
Utah Cancer Specialists Salt Lake City UT
Utah Valley Regional Medical Center Provo UT
Virtua-Memorial Hospital Burlington County, Inc. Mount Holly NJ
Warren Cancer Research Foundation-Oklahoma CCOP Tulsa OK
Waukesha Memorial Hospital Waukesha WI
Wayne State University-Karmanos Cancer Institute Detroit MI
Webber Cancer Center Warren MI
Wellmont Holston Valley Medical Center Kingsport TN
Wenatchee Valley Medical Center P.S. Wenatchee WA
West Allis Memorial Hospital West Allis WI
Wilford Hall USAF Medical Center Lackland AFB TX
William Beaumont Hospital / Troy Troy MI
Winchester Hospital Radiation Oncology Center Winchester MA
York Cancer Center York PA
Zablocki VA Medical Center-Wood Milwaukee WI
Updated: 4/7/2014

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