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RTOG 0920 Protocol Information

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A Phase III Study of Postoperative Radiation Therapy (IMRT) +/- Cetuximab for Locally-Advanced Resected Head and Neck Cancer
Principal Investigator: Mitchell Machtay, MD
Primary Objective:

Test whether the addition of cetuximab to radiation therapy will improve overall survival (OS) in postoperative patients with intermediate risk following surgery

Patient Population:

 Pathologically proven diagnosis of squamous cell carcinoma (including variants such as verrucous carcinoma, spindle cell carcinoma, carcinoma NOS, etc.) of the head/neck (oral cavity, oropharynx or larynx); clinical stage T2-T4a, N0-2, M0 or T1, N1-2, M0.

Target Accrual: 700
Current Accrual: 391
Status: Open to Accrual
Date: 11/5/2009
Participating Sites:
Abbott Northwestern Hospital Minneapolis MN
Adams Cancer Center Gettysburg PA
Akron City Hospital Akron OH
Akron General Medical Center Akron OH
Allan Blair Cancer Centre Regina, SK
Alta Bates Summit Medical Center - Summit Campus Oakland CA
Auburn Radiation Oncology Center Auburn CA
Baptist Hospital of Miami Miami FL
Bay Area Tumor Institute CCOP Oakland CA
Benefis Healthcare-Sletten Cancer Institute Great Falls MT
Beth Israel Medical Center New York NY
Billings Clinic Cancer Center Billings MT
Bixby Medical Center Adrian MI
Boston Medical Center MBCCOP Boston MA
Cancer Centers of the Carolinas-Andrews Greenville SC
Cancer Centers of the Carolinas-Faris Road Greenville SC
Cancer Centers of the Carolinas-Greer Radiation Oncology Greer SC
Cancer Centers of the Carolinas-Seneca Seneca SC
Cancer Centers of the Carolinas-Spartanburg Spartanburg SC
Cancer Research for the Ozarks CCOP Springfield MO
Cape Radiation Oncology Cape Girardeau MO
Centre Hospitalier de l`Université de Montréal-Notre Dame Montreal Quebec
Centre Hospitalier Universitaire de Sherbrooke Sherbrooke, Quebec
Cherry Tree Cancer Center Hanover PA
Christiana Care Health Services, Inc. CCOP Newark DE
Community Hospital East Indianapolis IN
Community Hospitals of Indiana Regional Cancer Care North Indianapolis IN
Dixie Medical Cancer Center East St. George UT
Dr. H. Bliss Murphy Cancer Centre St. John's, NL
East Bay Radiation Oncology Center Castro Valley CA
Edward Hines, Jr. VA Hospital Hines IL
Emory University Atlanta GA
Emory University Hospital Midtown Atlanta GA
Epic Care Dublin - Partners in Cancer Care Dublin CA
Epic Care Pleasant Hill - Partners in Cancer Care Pleasant Hill CA
Fairview Ridges Hospital Burnsville MN
Fairview Southdale Hospital Edina MN
Flower Hospital Sylvania OH
Fox Chase Virtua Health Cancer Treatment Center Voorhees NJ
Grady Memorial Hospital Atlanta GA
Greenville CCOP - Cancer Centers of the Carolinas-Eastside Greenville SC
Hennepin County Medical Center Minneapolis MN
Highland Hospital Rochester NY
Indiana University Health Ball Memorial Hospital, Inc. Muncie IN
Ingalls Memorial Hospital Harvey IL
Intermountain Medical Center Murray UT
JC Robinson, MD Regional Cancer Center San Pablo CA
Kalamazoo CCOP-West Michigan Cancer Center Kalamazoo MI
Kansas City CCOP Prairie Village KS
Langlade Hospital Cancer Center Antigo WI
LDS Hospital Salt Lake City UT
Lewis Cancer & Research Pavilion at St. Joseph's/Candler Savannah GA
Lima Memorial Hospital Lima OH
Logan Regional Hospital Logan UT
Loyola University Chicago Maywood IL
Maimonides Medical Center Brooklyn NY
Maplewood Cancer Center Maplewood MN
Marshall Radiation Oncology Center Cameron Park CA
Mayo Clinic Rochester MN
Mayo Clinic Arizona Phoenix AZ
Mayo Clinic in Arizona Scottsdale AZ
Mayo Clinic in Florida Jacksonville FL
McGill University Montreal
McKay-Dee Hospital Ogden UT
Medical College of Wisconsin Milwaukee WI
Medical University of Ohio Toledo OH
Memorial Medical Center Savannah GA
Memorial Sloan Kettering Cancer Center (MSKCC) at Phelps Sleepy Hollow NY
Memorial Sloan Kettering of Rockville Center Rockville NY
Memorial Sloan Kettering-Basking Ridge Basking Ridge NJ
Memorial Sloan-Kettering Cancer Center New York NY
Memorial Sloan-Kettering Cancer Center at Commack Commack NY
Mercy Cancer Center at St. Ann Toledo OH
Mercy General Radiation Oncology Center Sacramento CA
Mercy Hospital Coon Rapids MN
Mercy Medical Center Canton OH
Mercy San Juan Radiation Oncology Center Carmichael CA
Methodist Cancer Center Omaha NE
Metro-MN CCOP St. Louis Park MN
Montana Cancer Consortium CCOP Billings MT
Nevada Cancer Research Foundation CCOP Las Vegas NV
North Memorial Medical Center Robbinsdale MN
Ohio State University Medical Center Columbus OH
Parkridge University Radiation Oncology Rochester NY
Parkview Cancer Center - Parkview Hospital Fort Wayne IN
Peninsula Regional Medical Center Salisbury MD
Penrose Cancer Center, Penrose-St. Francis Health Services Colorado Springs CO
Pomona Valley Hospital Medical Center Pomona CA
Princess Margaret Hospital Toronto, Ontario
Radiation Oncology Associates Fort Wayne IN
Radiological Associates of Sacramento Sacramento CA
Rapid City Regional Hospital Rapid City SD
Regions Radiation Therapy St. Paul MN
Rice Memorial Hospital Willmar MN
Ridgeview Medical Center Waconia MN
Robinson Radiation Oncology Ravenna OH
Rocky Mountain Oncology Center Casper WY
Roseville Radiation Oncology Center Roseville CA
Saint Elizabeth Regional Medical Center Lincoln NE
Saint John's Hospital - HealthEast Maplewood MN
Saint Vincent Mercy Medical Center Toledo OH
Sands Cancer Center Canandaigua NY
Seattle Cancer Care Alliance Seattle WA
Skagit Valley Hospital Mount Vernon WA
Solano Radiation Oncology Center Vacaville CA
Southwest Virginia Regional Cancer Center Norton VA
St Johns Hospital, Cancer Institute Springfield IL
St Mary's Hospital & Medical Center Grand Junction CO
St. Charles Mercy Hospital Oregon OH
St. Louis University Hospital St. Louis MO
St. Peter's Medical Center New Brunswick NJ
Summa Health Center at Lake Medina Medina OH
Summa Health System Barberton Hospital Barberton OH
Texas Oncology - Austin Midtown Austin TX
Texas Oncology - Central South Austin Austin TX
Texas Oncology - Round Rock Cancer Center Round Rock TX
Texas Oncology - Seton Williamson Round Rock TX
Texas Oncology - South Austin Austin TX
The Cancer Center of Hawaii-Leeward Ewa Beach HI
The Cancer Center of Hawaii-Liliha Honolulu HI
The Chinese University of Hong Kong Shatin
The Kirklin Clinic at Acton Road Birmingham AL
The Ottawa Hospital Regional Cancer Centre Ottawa, Ontario
The Queen's Medical Center Honolulu HI
The Regional Cancer Center at Singing River Hospital System Pascagoula MS
Toledo Clinic Cancer Centers - Adrian Adrian MI
Toledo Clinic Cancer Centers - Maumee Maumee OH
Toledo Community Hospital Oncology Program CCOP Toledo OH
United Hospital St. Paul MN
Unity Hospital Fridley MN
Univ. of Miami Sylvester Comp Cancer Ctr-Deerfield Beach Deerfield Beach FL
University of Alabama at Birmingham Medical Center Birmingham AL
University of California Davis Medical Center Sacramento CA
University of California San Francisco San Francisco CA
University of Colorado Denver Aurora CO
University of Hawaii Cancer Research Center MBCCOP Honolulu HI
University of Illinois at Chicago Chicago IL
University of Kentucky Hospital Lexington KY
University of Miami Miller School of Medicine Miami FL
University of Michigan Medical Center Ann Arbor MI
University of Mississippi Medical Center Jackson MS
University of Nebraska Medical Center Omaha NE
University of Oklahoma Health Sciences Center Oklahoma City OK
University of Rochester Rochester NY
University of Texas at San Antonio San Antonio TX
University of Texas-MD Anderson Cancer Center Houston TX
University of Utah Health Science Center Salt Lake City UT
University of Washington Medical Center Seattle WA
University of Wisconsin Cancer Center Johnson Creek Johnson Creek WI
University of Wisconsin Hospital Madison WI
USON- New York Oncology Hematology, P.C. Albany NY
USON- Texas Oncology Arlington South Arlington TX
USON- Texas Oncology-Denton Denton TX
USON- Texas Oncology-Sugar Land Sugarland TX
USON-Arizona Radiation Oncology Tucson AZ
USON-Cancer Care Northwest - Spokane Spokane WA
USON-Cancer Care Northwest-East Holland Spokane WA
USON-Fort Worth Fort Worth TX
USON-Plano West Cancer Center Plano TX
USON-Texas Oncology - Houston Memorial City Houston TX
USON-Texas Oncology- Sherman Sherman TX
USON-Texas Oncology-Lewisville Flower Mound TX
USON-Williamette Valley Cancer Center Eugene OR
Utah Cancer Specialists Salt Lake City UT
Utah Valley Regional Medical Center Provo UT
Valley Medical Oncology Consultants Pleasanton CA
Virtua-Memorial Hospital Burlington County, Inc. Mount Holly NJ
Wausau Hospital Center Wausau WI
Welch Cancer Center Sheridan WY
Wellmont Holston Valley Medical Center Kingsport TN
Wenatchee Valley Medical Center P.S. Wenatchee WA
York Cancer Center York PA
Zablocki VA Medical Center-Wood Milwaukee WI
Updated: 4/16/2014

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