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RTOG 0937 Protocol Information

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Randomized Phase II Study Comparing Prophylactic Cranial Irradiation Alone To Prophylactic Cranial Irradiation And Consolidative Extra-Cranial Irradiation For Extensive Disease Small Cell Lung Cancer (ED-SCLC)
Principal Investigator: Elizabeth Gore, MD
Primary Objective:

To determine the 1-year overall median survival rate in patients with ED-SCLC with the administration of PCI alone versus PCI with consolidation extracranial RT following platinum-based chemotherapy

Patient Population:

Patients with extensive disease small cell lung cancer, excluding CNS metastases; patients must have had radiographic evidence of 1-4 extra-cranial metastatic lesions prior to platinum-based chemotherapy AND have had radiographic partial or complete response to chemotherapy in a minimum of one site of disease and no progression in any site.

Target Accrual: 154
Current Accrual: 76
Status: Open to Accrual
Date: 3/18/2010
Participating Sites:
Abbott Northwestern Hospital Minneapolis MN
Abington Memorial Hospital Abington PA
Adena Regional Medical Center Chillicothe OH
Akron City Hospital Akron OH
Akron General Medical Center Akron OH
Allan Blair Cancer Centre Regina, SK
Anderson Memorial Hospital Anderson SC
Aria Health Philadelphia PA
Auburn Radiation Oncology Center Auburn CA
BC Cancer Agency Center for Southern Interior Kelowna, BC
Benefis Healthcare-Sletten Cancer Institute Great Falls MT
Billings Clinic Cancer Center Billings MT
Bixby Medical Center Adrian MI
Borgess Medical Center Kalamazoo MI
Boston Medical Center MBCCOP Boston MA
British Columbia Cancer Agency-Vancouver Cancer Center Vancouver, BC
Bronson Battle Creek Battle Creek MI
Bronson Methodist Hospital Kalamazoo MI
Cancer Centers of the Carolinas-Andrews Greenville SC
Cancer Centers of the Carolinas-Faris Road Greenville SC
Cancer Centers of the Carolinas-Greer Radiation Oncology Greer SC
Cancer Centers of the Carolinas-Seneca Seneca SC
Cancer Centers of the Carolinas-Spartanburg Spartanburg SC
Cape Radiation Oncology Cape Girardeau MO
Carle Cancer Center CCOP Urbana IL
Cleveland Clinic Cancer Center/Fairview Hospital Cleveland OH
Cleveland Clinic Cancer Center-Independence Independence OH
Cleveland Clinic Foundation Cleveland OH
Cleveland Clinic Wooster Specialty Center Wooster OH
Coastal Carolina Radiation Oncology Center Wilmington NC
Columbia-Presbyterian Medical Center New York NY
Columbus Community Clinical Oncology Program Columbus OH
Community Hospital East Indianapolis IN
Community Hospitals of Indiana Regional Cancer Care North Indianapolis IN
Cooper Health System Camden NJ
Cooper Health System-Voorhees Voorhees NJ
Doctor's Hospital Columbus OH
Dubs Cancer Center @ Rogue Valley Medical Center Medford OR
Elliot Hospital Manchester NH
Emory University Atlanta GA
Emory University Hospital Midtown Atlanta GA
Fairview Ridges Hospital Burnsville MN
Fairview Southdale Hospital Edina MN
Florida Hospital Orlando FL
Florida Radiation Oncology Group - Baptist Regional Jacksonville FL
Flower Hospital Sylvania OH
Forsyth Regional Medical Center Winston Salem NC
Genesis Healthcare System Zainesville OH
Gibbs Cancer Center-Pelham Greer SC
Grady Memorial Hospital Atlanta GA
Grady Memorial Hospital Delaware OH
Grand Rapids Clinical Oncology Program (GRCOP) Grand Rapids MI
Grant Medical Center Columbus OH
Greater Baltimore Medical Center Baltimore MD
Greenville CCOP - Cancer Centers of the Carolinas-Eastside Greenville SC
Hennepin County Medical Center Minneapolis MN
Highland Hospital Rochester NY
Hillcrest Hospital Cancer Center Mayfield Heights OH
Holy Redeemer Hospital Meadowbrook PA
ICON – Baptist Medical Center South Jacksonville FL
ICON – Cancer Center of Putnam Palatka FL
ICON – Flagler Cancer Center St Augustine FL
ICON – Florida Cancer Center - Beaches Jacksonville Beach FL
ICON – Orange Park Cancer Center Orange Park FL
ICON – Southside Cancer Center Jacksonville FL
Indiana University Health Ball Memorial Hospital, Inc. Muncie IN
Ingalls Memorial Hospital Harvey IL
Interim LSU Public Hospital (ILH-NO) New Orleans LA
Iredell Memorial Hospital Statesville NC
James Graham Brown Cancer Ctr at University of Louisville Louisville KY
Johns Hopkins Hospital Baltimore MD
Kalamazoo CCOP-West Michigan Cancer Center Kalamazoo MI
Kalispell Regional Medical Center Kalispell MT
Lake/University Seidman Cancer Center Mentor OH
Lewis Cancer & Research Pavilion at St. Joseph's/Candler Savannah GA
Lewis Cancer & Research Pavilion-Hilton Head/Blufton Hilton Head Island SC
Licking Memorial Hospital Newark OH
Lima Memorial Hospital Lima OH
Lowell General Hospital Cancer Center Lowell MA
LSU Health Science Center-New Orleans MB-CCOP New Orleans LA
Maimonides Medical Center Brooklyn NY
Maplewood Cancer Center Maplewood MN
Marietta Memorial Hospital Marietta OH
Marshall Radiation Oncology Center Cameron Park CA
Mary Bird Perkins Cancer Center Baton Rouge LA
Mayo Clinic Arizona Phoenix AZ
Mayo Clinic Health System-Franciscan Healthcare LaCrosse WI
Mayo Clinic in Arizona Scottsdale AZ
McGill University Montreal
McMaster Univ, Juravinski Can Ctr, Hamilton Health Sciences Hamilton, Ontario
Medical College of Wisconsin Milwaukee WI
Medical University of Ohio Toledo OH
Mercy Cancer Center Elyria OH
Mercy Cancer Center at St. Ann Toledo OH
Mercy General Radiation Oncology Center Sacramento CA
Mercy Health Partners-Johnson Family Center Muskegon MI
Mercy Hospital Coon Rapids MN
Mercy Hospital St. Louis St Louis MO
Mercy San Juan Radiation Oncology Center Carmichael CA
Mercy-Springfield Springfield MO
Metro-MN CCOP St. Louis Park MN
Mid Ohio Oncology Hematology Inc- Mark H. Zangmeister Ctr Cols OH
Montana Cancer Consortium CCOP Billings MT
Mount Carmel Medical Center-State Street Columbus OH
Mount Carmel-St. Ann's Cancer Center Westerville OH
National University Cancer Institute Singapore Singapore
New Hanover Regional Medical Center Wilmington NC
New York Methodist Hospital Brooklyn NY
New York University Hospital New York NY
North Memorial Medical Center Robbinsdale MN
Northeast Radiation Oncology Center Dunmore PA
Northwestern Memorial Hospital Chicago IL
Ochsner Clinic CCOP New Orleans LA
Ohio State University Medical Center Columbus OH
Park Ridge Health Hendersonville NC
Parkridge University Radiation Oncology Rochester NY
Parkview Cancer Center - Parkview Hospital Fort Wayne IN
Peninsula Regional Medical Center Salisbury MD
Penrose Cancer Center, Penrose-St. Francis Health Services Colorado Springs CO
Poudre Valley Hospital Radiation Oncology Fort Collins CO
Presbyterian Hospital Charlotte NC
Princess Margaret Hospital Toronto, Ontario
Radiation Oncology Associates Fort Wayne IN
Radiological Associates of Sacramento Sacramento CA
Regions Radiation Therapy St. Paul MN
Renown Regional Medical Center Reno NV
Rice Memorial Hospital Willmar MN
Ridgeview Medical Center Waconia MN
Riverside Methodist Hospital Columbus OH
Robinson Radiation Oncology Ravenna OH
Rockingham Memorial Hospital Hahn Cancer Center Harrisonburg VA
Rocky Mountain Oncology Center Casper WY
Roseville Radiation Oncology Center Roseville CA
Rutherford Hospital Inc. Rutherfordton NC
Saint John's Hospital - HealthEast Maplewood MN
Saint Mary's Health Care/Hospital Grand Rapids MI
Saint Vincent Mercy Medical Center Toledo OH
Sands Cancer Center Canandaigua NY
Saskatoon Cancer Centre Saskatoon, Saskatchew
Solano Radiation Oncology Center Vacaville CA
South Atlantic Radiation Oncology Supply NC
Southern Ohio Medical Center - Cancer Center Portsmouth OH
Sparta Cancer Center Sparta NJ
Spartanburg Regional Medical Center Spartanburg SC
Spectrum Health-Grand Rapid Clinical Oncology Program Grand Rapids MI
Springfield Regional Medical Center Springfield OH
St Johns Hospital, Cancer Institute Springfield IL
St. Agnes Healthcare Baltimore MD
St. Charles Mercy Hospital Oregon OH
St. Joseph Medical Center Towson MD
St. Louis University Hospital St. Louis MO
St. Lukes Hospital Association of Duluth Duluth MN
St. Vincent Anderson Regional Hospital, Inc. Anderson IN
Stanford University Medical Center Palo Alto CA
Summa Health Center at Lake Medina Medina OH
Summa Health System Barberton Hospital Barberton OH
The Regional Cancer Center at Singing River Hospital System Pascagoula MS
Thomas Jefferson University Hospital Philadelphia PA
Toledo Clinic Cancer Centers - Adrian Adrian MI
Toledo Clinic Cancer Centers - Maumee Maumee OH
Toledo Community Hospital Oncology Program CCOP Toledo OH
Touro Infirmary New Orleans LA
Trinity Cancer Care Center Minot ND
Tulane University Medical Center New Orleans LA
UH Seidman Cancer Center at Southwest General Middleburgh OH
UHHS - Chagrin Highlands Orange Village OH
UHHS - Westlake Medical Center Westlake OH
United Hospital St. Paul MN
Unity Hospital Fridley MN
University Hospitals of Cleveland Cleveland OH
University of Cincinnati Cincinnati OH
University of Colorado Denver Aurora CO
University of Kentucky Hospital Lexington KY
University of Maryland Medical Systems Baltimore MD
University of Mississippi Medical Center Jackson MS
University of Nebraska Medical Center Omaha NE
University of North Carolina - Chapel Hill Chapel Hill NC
University of Rochester Rochester NY
University of Texas Medical Branch Galveston TX
University of Wisconsin Cancer Center Johnson Creek Johnson Creek WI
University of Wisconsin Hospital Madison WI
University Pointe-Precision Radiotherapy West Chester OH
Upper Delaware Valley Cancer Center Milford PA
Upstate Carolina CCOP - Gibbs Regional Cancer Center Spartanburg SC
UTMB Cancer Center at Victory Lakes League City TX
Warren Cancer Research Foundation-Oklahoma CCOP Tulsa OK
Welch Cancer Center Sheridan WY
Wheaton Franciscan Cancer Care-All Saints Racine WI
Zablocki VA Medical Center-Wood Milwaukee WI
Updated: 4/14/2014

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