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RTOG 0937 Protocol Information

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Randomized Phase II Study Comparing Prophylactic Cranial Irradiation Alone To Prophylactic Cranial Irradiation And Consolidative Extra-Cranial Irradiation For Extensive Disease Small Cell Lung Cancer (ED-SCLC)
Principal Investigator: Elizabeth Gore, MD
Primary Objective:

To determine the 1-year overall median survival rate in patients with ED-SCLC with the administration of PCI alone versus PCI with consolidation extracranial RT following platinum-based chemotherapy

Patient Population:

Patients with extensive disease small cell lung cancer, excluding CNS metastases; patients must have had radiographic evidence of 1-4 extra-cranial metastatic lesions prior to platinum-based chemotherapy AND have had radiographic partial or complete response to chemotherapy in a minimum of one site of disease and no progression in any site.

Target Accrual: 154
Current Accrual: 85
Status: Open to Accrual
Date: 3/18/2010
Participating Sites:
Abbott Northwestern Hospital Minneapolis MN
Abington Memorial Hospital Abington PA
ACR Clinical Research Center Philadelphia PA
Adams Cancer Center Gettysburg PA
Adena Regional Medical Center Chillicothe OH
Adventist Medical Center Portland OR
Akron City Hospital Akron OH
Akron General Medical Center Akron OH
Allan Blair Cancer Centre Regina, SK
Allegiance Health/W.A. Foote Memorial Hospital Jackson MI
Anderson Memorial Hospital Anderson SC
Aria Health Philadelphia PA
Asante Health System Medford OR
Asante Rogue Regional Medical Center Medford OR
Asante Three Rivers Medical Center Grants Pass OR
Auburn Radiation Oncology Center Auburn CA
Barnes Jewish West County Hospital St. Louis MO
Bay Medical Center Panama City FL
Bay Medical Center Panama City FL
BC Cancer Agency Center for Southern Interior Kelowna, BC
Benefis Healthcare-Sletten Cancer Institute Great Falls MT
Billings Clinic Billings MT
Billings Clinic Cancer Center Billings MT
Bixby Medical Center Adrian MI
Borgess Medical Center Kalamazoo MI
Boston Medical Center MBCCOP Boston MA
Bozeman Deaconess Hospital Bozeman MT
Bozeman Deaconess Hospital Cancer Center Bozeman MT
British Columbia Cancer Agency-Vancouver Cancer Center Vancouver, BC
Bronson Battle Creek Battle Creek MI
Bronson Methodist Hospital Kalamazoo MI
Bryn Mawr Hospital Bryn Mawr PA
Bryn Mawr Hospital Bryn Mawr PA
Cancer Research for the Ozarks CCOP Springfield MO
Cape Radiation Oncology Cape Girardeau MO
Carle Cancer Center Urbana IL
Carle Cancer Center CCOP Urbana IL
Center for Cancer Care @ Goshen Health System Goshen IN
Cherry Tree Cancer Center Hanover PA
Clackamas Radiation Oncology Center Clackamas OR
Cleveland Clinic Cancer Center/Fairview Hospital Cleveland OH
Cleveland Clinic Cancer Center-Independence Independence OH
Cleveland Clinic Foundation Cleveland OH
Cleveland Clinic Foundation- Parma Parma OH
Cleveland Clinic Wooster Specialty Center Wooster OH
Cleveland Clinic-Strongsville Strongsville OH
Coastal Carolina Radiation Oncology Center Wilmington NC
Columbia River CCOP Portland OR
Columbia-Presbyterian Medical Center New York NY
Columbus Community Clinical Oncology Program Columbus OH
Community Hospital East Indianapolis IN
Community Hospitals of Indiana Regional Cancer Care North Indianapolis IN
Community Medical Center Toms River NJ
Cooper Health System Camden NJ
Cooper Health System-Voorhees Voorhees NJ
Cross Cancer Institute Edmonton, Alberta
D.N. Greenwald Mukwonago WI
Doctor's Hospital Columbus OH
Dubs Cancer Center @ Rogue Valley Medical Center Medford OR
Elliot Hospital Manchester NH
Emory University Atlanta GA
Emory University Hospital Midtown Atlanta GA
Emory University/Winship Cancer Institute Atlanta GA
Fairview Ridges Hospital Burnsville MN
Fairview Southdale Hospital Edina MN
Florida Hospital Orlando FL
Florida Radiation Oncology Group - Baptist Regional Jacksonville FL
Flower Hospital Sylvania OH
Flower Hospital Sylvania OH
Forsyth Regional Medical Center Winston Salem NC
Fox Chase Cancer Center Philadelphia PA
Fox Chase Cancer Center-Buckingham Furlong PA
Genesis Healthcare System Zainesville OH
Genesys Regional Medical Center Flint MI
Gibbs Cancer Center-Pelham Greer SC
Grady Health System Atlanta GA
Grady Memorial Hospital Delaware OH
Grady Memorial Hospital Atlanta GA
Grand Rapids Clinical Oncology Program (GRCOP) Grand Rapids MI
Grant Medical Center Columbus OH
Greater Baltimore Medical Center Baltimore MD
Greenville Health System Cancer Institute-Andrews Greenville SC
Greenville Health System Cancer Institute-Faris Greenville SC
Greenville Health System Cancer Institute-Greer Radiation Greer SC
Greenville Health System Cancer Institute-International Greenville SC
Greenville Health System Cancer Institute-Seneca Seneca SC
Greenville Health System Cancer Institute-Spartanburg Spartanburg SC
Gunderson Clinic La Crosse WI
Harrison Memorial Hospital Bremerton WA
Hennepin County Medical Center Minneapolis MN
Henry Ford Hospital Detroit MI
Henry Ford Macomb Hospital Clinton Township MI
Highland Hospital Rochester NY
Hillcrest Hospital Cancer Center Mayfield Heights OH
Holy Redeemer Hospital Meadowbrook PA
Hurley Cancer Center Flint MI
Huron Valley Hospital Commerce Township MI
ICON – Baptist Medical Center South Jacksonville FL
ICON – Cancer Center of Putnam Palatka FL
ICON – Flagler Cancer Center St Augustine FL
ICON – Florida Cancer Center - Beaches Jacksonville Beach FL
ICON – Orange Park Cancer Center Orange Park FL
ICON – Southside Cancer Center Jacksonville FL
Idaho Urologic Institute Meridian ID
Image-Guided Therapy QA Center (ITC) St. Louis MO
Indiana University Health Ball Memorial Hospital, Inc. Muncie IN
Ingalls Memorial Hospital Harvey IL
Integris Cancer Institute of Oklahoma Oklahoma City OK
Interim LSU Public Hospital (ILH-NO) New Orleans LA
Iredell Memorial Hospital Statesville NC
James Graham Brown Cancer Ctr at University of Louisville Louisville KY
Jersey Shore University Medical Center Neptune NJ
John H. Stroger, Jr. Hospital of Cook County MBCCOP Chicago IL
Johns Hopkins Hospital Baltimore MD
Johns Hopkins University-Sidney Kimmel Cancer Center Baltimore MD
Kalamazoo CCOP-West Michigan Cancer Center Kalamazoo MI
Kalispell Regional Medical Center Kalispell MT
Lake/University Seidman Cancer Center Mentor OH
Lankenau Hospital Wynnewood PA
Lankenau Hospital Wynnewood PA
Legacy Meridian Park Hospital Tualatin OR
Lewis Cancer & Research Pavilion at St. Joseph's/Candler Savannah GA
Lewis Cancer & Research Pavilion-Hilton Head/Blufton Hilton Head Island SC
Licking Memorial Hospital Newark OH
Lima Memorial Hospital Lima OH
London Regional Cancer Program London Ontario
Lowell General Hospital Cancer Center Lowell MA
LSU Health Science Center-New Orleans MB-CCOP New Orleans LA
Maimonides Medical Center Brooklyn NY
Main Line CCOP Wynnewood PA
Mainline Health CCOP Wynnewood PA
Maplewood Cancer Center Maplewood MN
Margaret R. Pardee Memorial Hospital Hendersonville NC
Marietta Memorial Hospital Marietta OH
Marshall Radiation Oncology Center Cameron Park CA
Mary Bird Perkins Cancer Center Baton Rouge LA
Mayo Clinic Arizona Phoenix AZ
Mayo Clinic Health System-Franciscan Healthcare LaCrosse WI
Mayo Clinic in Arizona Scottsdale AZ
McGill University Montreal
McLaren Cancer Institute - Flint Flint MI
McLaren Cancer Institute - Lapeer Lapeer MI
McLaren Cancer Institute - Owosso Owosso MI
McLaren Cancer Institute-Owosso Owosso MI
McMaster Univ, Juravinski Can Ctr, Hamilton Health Sciences Hamilton, Ontario
MD Anderson Cancer Center Orlando Orlando FL
Medical College of Wisconsin Milwaukee WI
Medical University of Ohio Toledo OH
Mercy Cancer Center Elyria OH
Mercy Cancer Center at St. Ann Toledo OH
Mercy General Radiation Oncology Center Sacramento CA
Mercy Health Partners-Johnson Family Center Muskegon MI
Mercy Hospital Coon Rapids MN
Mercy Hospital Port Huron Port Huron MI
Mercy Hospital St. Louis St Louis MO
Mercy San Juan Radiation Oncology Center Carmichael CA
Mercy-Springfield Springfield MO
Methodist Cancer Center Omaha NE
Methodist Hospital Philadelphia PA
Metro-MN CCOP St. Louis Park MN
Michigan Cancer Research Consortium CCOP Ann Arbor MI
Mid Ohio Oncology Hematology Inc- Mark H. Zangmeister Ctr Cols OH
Montana Cancer Consortium CCOP Billings MT
Mount Carmel Medical Center-State Street Columbus OH
Mount Carmel-St. Ann's Cancer Center Westerville OH
National University Cancer Institute Singapore Singapore
Nevada Cancer Research Foundation CCOP Las Vegas NV
New Hanover Regional Medical Center Wilmington NC
New Mexico Cancer Care Alliance Albuquerque NM
New York Methodist Hospital Brooklyn NY
New York University Hospital New York NY
North Coast Cancer Care Sandusky OH
North Memorial Medical Center Robbinsdale MN
Northeast Radiation Oncology Center Dunmore PA
Northeastern Ontario Regional Cancer Centre Sudbury, Ontario
Northern Rockies Radiation Oncology Center Billings MT
Northridge Hospital Medical Center Northridge CA
Northwest Cancer Specialists-Vancouver Vancouver WA
Northwestern Memorial Hospital Chicago IL
Oakwood Healthcare Inc Dearborn MI
Ocean Medical Center Brick NJ
Ochsner Clinic CCOP New Orleans LA
Oconomowoc Memorial Hospital - ProHealth Care Inc. Oconomowoc WI
Ohio State University Medical Center Columbus OH
Pacific Cancer Institute Wailuku HI
Paoli Memorial Hospital Paoli PA
Park Ridge Health Hendersonville NC
Parkridge University Radiation Oncology Rochester NY
Parkview Cancer Center - Parkview Hospital Fort Wayne IN
Parkview Hospital Fort Wayne IN
PeaceHealth Southwest Medical Center Vancouver WA
Peninsula Regional Medical Center Salisbury MD
Penrose Cancer Center, Penrose-St. Francis Health Services Colorado Springs CO
Poudre Valley Hospital Radiation Oncology Fort Collins CO
Presbyterian Hospital Charlotte NC
Princess Margaret Hospital Toronto, Ontario
Providence Cancer Center Medford OR
Providence Holy Cross Medical Center Mission Hills CA
Providence Milwaukie Hospital Milwaukie OR
Providence Portland Medical Center Portland OR
Providence St. Vincent Medical Center Portland OR
Rabin Medical Center-Davidoff Cancer Center Petah Tikva
Radiation Oncology Associates Fort Wayne IN
Radiation Oncology Associates PC Fort Wayne IN
Radiological Associates of Sacramento Sacramento CA
Radiological Physics Center (RPC) Houston TX
Rapid City Regional Hospital Rapid City SD
Regions Radiation Therapy St. Paul MN
Renown Regional Medical Center Reno NV
Rice Memorial Hospital Willmar MN
Ridgeview Medical Center Waconia MN
Riverside Methodist Hospital Columbus OH
Riverview Medical Center/Riverview Regional Cancer Center Red Bank NJ
Robinson Radiation Oncology Ravenna OH
Rockingham Memorial Hospital Hahn Cancer Center Harrisonburg VA
Rocky Mountain Oncology Center Casper WY
Roseville Radiation Oncology Center Roseville CA
Rutherford Hospital Inc. Rutherfordton NC
Saint Agnes Medical Center Fresno CA
Saint Alphonsus Regional Medical Center Boise ID
Saint Barnabas Medical Center Livingston NJ
Saint James Community Hospital and Cancer Treatment Center Butte MT
Saint John's Hospital - HealthEast Maplewood MN
Saint Mary's Health Care/Hospital Grand Rapids MI
Saint Peter's Community Hospital Helena MT
Saint Vincent Mercy Medical Center Toledo OH
Sands Cancer Center Canandiaqua NY
Sands Cancer Center Canandaigua NY
Saskatoon Cancer Centre Saskatoon, Saskatchew
Siteman Cancer Center - South County St Louis MO
Solano Radiation Oncology Center Vacaville CA
South Atlantic Radiation Oncology Supply NC
South Atlantic Radiation Oncology Supply NC
Southern Ohio Medical Center - Cancer Center Portsmouth OH
Sparrow Regional Cancer Center Lansing MI
Sparta Cancer Center Sparta NJ
Spartanburg Regional Medical Center Spartanburg SC
Spectrum Health-Grand Rapid Clinical Oncology Program Grand Rapids MI
Springfield Regional Medical Center Springfield OH
Springfield Regional Medical Center Springfield OH
St Francis Hospital & Medical Center Hartford CT
St Johns Hospital, Cancer Institute Springfield IL
St. Agnes Healthcare Baltimore MD
St. Charles Mercy Hospital Oregon OH
St. Johns Hospital & Medical Center Grosse Pointe Woods MI
St. Joseph Medical Center Towson MD
St. Joseph Mercy Hospital Ann Arbor MI
St. Joseph Mercy Oakland Pontac MI
St. Louis University Hospital St. Louis MO
St. Lukes Hospital Association of Duluth Duluth MN
St. Mary Mercy Hospital Livonia MI
St. Mary`s Medical Center Saginaw MI
St. Vincent Anderson Regional Hospital, Inc. Anderson IN
St. Vincent Hospital and Health Care Centers, Inc. Indianapolis IN
Stanford University Medical Center Palo Alto CA
Summa Health Center at Lake Medina Medina OH
Summa Health System Barberton Hospital Barberton OH
Tel-Aviv Sourasky Medical Center Tel-Aviv
Texas Oncology - Austin Midtown Austin TX
Texas Oncology - Central South Austin Austin TX
Texas Oncology - Round Rock Cancer Center Round Rock TX
Texas Oncology - Seton Williamson Round Rock TX
Texas Oncology - South Austin Austin TX
The Cancer Center of Hawaii-Leeward Ewa Beach HI
The Cancer Center of Hawaii-Liliha Honolulu HI
The Hospital of Central Connecticut New Britain CT
The James Graham Brown Cancer Center at University of Louisville Louisville KY
The Prostate Center King of Prussia PA
The Queen's Medical Center Honolulu HI
The Regional Cancer Center at Singing River Hospital System Pascagoula MS
The Schiffler Cancer Center Wheeling WV
Thomas Jefferson University Hospital Philadelphia PA
Toledo Clinic Cancer Centers - Adrian Adrian MI
Toledo Clinic Cancer Centers - Maumee Maumee OH
Toledo Clinic Cancer Centers-Bowling Green Bowling Green OH
Toledo Community Hospital Oncology Program CCOP Toledo OH
Toledo Radiation Oncology at Northwest Ohio Onocolgy Center
Touro Infirmary New Orleans LA
Trinity Cancer Care Center Minot ND
Tulane University Medical Center New Orleans LA
U.W. Cancer Center - Riverview Wisconsin Rapids WI
UH Seidman Cancer Center at Geauga Medical Center Chardon OH
UH Seidman Cancer Center at Southwest General Middleburgh OH
UHHS - Chagrin Highlands Orange Village OH
UHHS - Westlake Medical Center Westlake OH
United Hospital St. Paul MN
Unity Hospital Fridley MN
Univ of Kansas Comprehensive Cancer Center Kansas City KS
University Health Network-Princess Margaret Hospital Toronto
University Hospitals of Cleveland Cleveland OH
University of Cincinnati Cincinnati OH
University of Colorado Denver Aurora CO
University of Florida College of Medicine Gainesville FL
University of Florida Health Science Center Jacksonville FL
University of Hawaii Honolulu HI
University of Hawaii Cancer Research Center MBCCOP Honolulu HI
University of Kansas Cancer Center - Southwest Overland Park KS
University of Kansas Cancer Center-North Kansas City MO
University of Kansas Cancer Center-South Kansas City MO
University of Kentucky Lexington KY
University of Kentucky Hospital Lexington KY
University of Maryland Medical Systems Baltimore MD
University of Mississippi Medical Center Jackson MS
University of Nebraska Medical Center Omaha NE
University of North Carolina - Chapel Hill Chapel Hill NC
University of Rochester Rochester NY
University of Texas Medical Branch Galveston TX
University of Texas Medical Branch Galveston TX
University of Texas Southwestern Medical Center Dallas TX
University of Texas Southwestern Medical School Dallas TX
University of Wisconsin Cancer Center Johnson Creek Johnson Creek WI
University of Wisconsin Hospital Madison WI
University Pointe-Precision Radiotherapy West Chester OH
University Radiation Oncology Rochester NY
Upper Delaware Valley Cancer Center Milford PA
Upstate Carolina CCOP - Gibbs Regional Cancer Center Spartanburg SC
USON- Cancer Care Centers of South Texas-NE San Antonio TX
USON- New York Oncology Hematology, P.C. Albany NY
USON- Northwest Cancer Specialist-Portland Portland OR
USON- Texas Oncology Arlington South Arlington TX
USON- Texas Oncology Longview Cancer Center Longview TX
USON- Texas Oncology-Denton Denton TX
USON- Texas Oncology-Sugar Land Sugarland TX
USON- Texas Oncology-Tyler Tyler TX
USON-Arizona Radiation Oncology Tucson AZ
USON-Fort Worth Fort Worth TX
USON-Texas Oncology - Houston Memorial City Houston TX
USON-Texas Oncology- Sherman Sherman TX
USON-Texas Oncology-Lewisville Flower Mound TX
USON-Texas Oncology-Wichita Falls Texoma Cancer Center Wichita Falls TX
UTMB Cancer Center at Victory Lakes League City TX
UTMB Cancer Center at Victory Lakes League City TX
Vancouver Island Cancer Centre Victoria, BC
Wake Forest University Baptist Medical Center Winston-Salem NC
Warren Cancer Research Foundation-Oklahoma CCOP Tulsa OK
Washington University St. Louis MO
Waukesha Memorial Hospital Waukesha WI
Wayne State University-Karmanos Cancer Institute Detroit MI
Webber Cancer Center Warren MI
Welch Cancer Center Sheridan WY
Wheaton Franciscan Cancer Care-All Saints Racine WI
York Cancer Center York PA
Zablocki VA Medical Center-Wood Milwaukee WI
Updated: 7/15/2014

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