Taking part in a research study is voluntary. Patients may choose not to take part or may leave a study at any time. If a patient wishes to stop participating in the study, the patient should first discuss this with his/her doctor. In order to provide important information that may add to the analysis of the study, the doctor may ask permission to submit follow-up data as it relates to the study. Patients may accept or refuse this request. Leaving the study will not result in any penalty or loss of benefits.