#2

SUMMARY OF CHANGES

RTOG 96-02 Brain/Taxol January 31, 1997



The following changes are in effect:

Section 3.2.5 Changed to

Section 7.1 Bristol-Myers-Squibb (BMS) will notroutinely provide taxol. In instances of extreme hardship, apply to BMS for patient-specific consideration. This change affects Secions 7.1.1-2.




#1

SUMMARY OF CHANGES

RTOG 96-02 Brain/Taxol October 25, 1996



The following changes are in effect:

Eligibility Checklist Q 3-5 were rearranged

Section 7.1.6.2 Added

Individual treating physician may substitute Ranitidine, Famotidine, or oral dexamethasone at their discretion.

Section 7.2.7 (new) Modifications for neuropathy were added.


Replacement pages are attached.