1	Drug Procurement and Accountability
2	Drug Supply Sources Pharmaceutical Companies NCI Commercially available products
3	Pharmaceutical Company Supplied Drug Procurement Procedure varies by study. Detailed instructions for obtaining drug can be found in Section 7.0 of the protocol First step usually requires faxing the Study Agent Shipment Form (SASF) to CTSU (US) or RTOG (Canada). RTOG Processing of this form approves the site as eligible to receive drug Registration/Randomization is generally the trigger for the initial shipment
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6	Pharmaceutical Company Supplied Drug Procurement Realistic Treatment Start Dates If the SASF has already been processed, drug is generally shipped for overnight or two day delivery. Most distributors will not ship prior to a weekend or holiday. Shipments are limited between December 23 and January 1.
7	Pharmaceutical Company Supplied Drug Procurement Submitting your SASF for processing as soon as the individual responsible for the drug at your institution has been identified will assist you in: avoiding delays in the initial drug shipment alleviating frustration and inconvenience for yourself and most importantly the patient
8	NCI NCI sponsored studies The Pharmaceutical Management Branch (PMB) of the NCI is responsible for supplying study agent for NCI trials. NIH Form 986/Clinical Drug Request is used to order study drug for NCI sponsored trials All NCI Forms are available on the NCI website at http://ctep.cancer.gov/requisition/storage.html Clinical Drug Request Investigational Agent Accountability Record Drug Return Drug Transfer
9	NCI Investigators must be registered with the NCI and have an Investigator NCI Number to receive drug from the NCI. This requires the annual submission of: FDA 1572 with CVs signed Supplemental Investigator Data Form (IDF) Financial Disclosure Form NCI/PMB Contact Information: Phone: (301) 496-5725 Fax: (301) 402-0429
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11	Commercially Available Products Supplied free of charge through pharmaceutical support OR Obtained via prescription from the physician Usually covered by patient’s prescription plan
12	Investigational Drug Sponsors & Support NCI ACR/RTOG Pharmaceutical Companies
13	Drug Accountability Varies by sponsor/protocol Records of accountability documentation Receipt of Drug Dispensation of Drug Disposition of Drug (returned/destroyed used/unused) Instructions usually documented in the protocol