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RTOG Translational Research Program

The RTOG Translational Research Program (TRP) Committee was created to combine and strengthen coordination among the basic sciences committees, including tumor biology, chemical and biological modifiers, and pathology. Its major goal is to promote communication of scientific ideas for the research laboratory into protocol design of the group. Specific aims of the TRP are to (1) act as a resource for new ideas; (2) educate members about emerging information on tumor behavior, molecular mechanisms and recent links between therapy treated with chemoradiation; (3) integrate new information into protocol design; and (4) conduct correlative studies and evaluate protocols results to enhance and expand hypotheses being tested.

The TRP Committee organizes symposia to educate RTOG members about basic science principles used in current protocols under investigation and about new techniques that may be incorporated into protocols in the future. At each semi-annual RTOG meeting, a keynote scientific address is given on a topic of interest to the group. In the summer, this topic is chosen to coincide with the subject being discussed by the translational research program at that meeting.

Translational Research Program (TRP): Request for Applications (RFA)

This RFA invites applications to conduct translational research using material obtained from prospective clinical trials conducted by the Radiation Therapy Oncology Group (RTOG), a National Cancer Institute (NCI) funded cooperative group (www.rtog.org). This RFA is offered by the RTOG Translational Research Program (TRP). We encourage investigators not previously collaborating with the RTOG to undertake cooperative investigations with the RTOG. In addition, we are especially interested in developing technologies that may be tested in a prospective multi-institutional cooperative group setting.

Eligible organizations include domestic for-profit or non-profit organizations, public or private institutions (e.g., universities, colleges, hospitals), units of state and local governments, and eligible agencies of the federal government. Foreign institutions are also eligible to apply. Eligible principal investigators include any individual with the skills, knowledge, and resources necessary to carry out the proposed research. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are encouraged to apply.

Complete TRP RFA [PDF]

The TRP RFA aims to stimulate laboratory-based research in RTOG clinical trials. The maximum amount available for each award is $50,000. Funds are intended to support laboratory studies that relate to trials that have proceeded through the various disease and modality committees and have been or are in the process of being activated. Funds may be used for technical support, supplies and minor equipment but not for salary support of the applicant or institutional indirect costs.

How To Apply for A TRP Seed Grant

  1. Download and complete the TRP Project Application Form.

  2. If also requesting specimens from the RTOG Tissue bank, check for tissue availability.

  3. Submit to RTOG Headquarters.
    • E-mail: RTOG-TRP@acr-arrs.org
    • Fax: (215) 928-0153 (ATTN: RTOG TRP)
    • Postal mail:
      RTOG Headquarters
      1818 Market Street, 16th Floor
      Philadelphia, PA 19103-3604
      ATTN: TRP

TRP Steering Committee
ChairAdam P. Dicker, M.D., Ph.D. adamdicker@mac.com
Co-ChairPaul Okunieff, M.D. okunieff@radonc.medinfo.rochester.edu
Co-ChairMark W. Dewhirst, DVM, Ph.D.dewhirst@radonc.duke.edu

TRP Subcommittee Liaisons (For more information about a specific TRP subcommittee, click on its link, if available.)

BioinformaticsJoseph O. Deasy, Ph.D. deasy@radonc.wustl.edu
 
BrainArnab Chakravarti, M.D. achakravarti@partners.org
Kevin Camphausen, M.D. camphauk@mail.nih.gov
Paul S. Mischel, M.D. PMischel@mednet.ucla.edu
 
BreastWendy Woodward, MD, Ph.D. wwoodward@mdanderson.org
 
EORTCEORTC Eric Deutsch, M.D., Ph.D. eric.deutsch@igr.fr
 
GIChandan Guha, M.D. cguha@montefiore.org
Sunil Krishnan, M.D. skrishnan@mdanderson.org
 
GUAlan Pollack, M.D., Ph.D. alan.pollack@fccc.edu
 
GYNJoanne Weidhaas, M.D., Ph.D. Joanne.Weidhaas@yale.edu
 
Head & Neck Christine H. Chung, M.D. Christine.Chung@Vanderbilt.edu
 
IGRTLaura Dawson, M.D.laura.dawson@rmp.uhn.on.ca
 
LungQuynh-Thu Xuan Le, M.D. qle@stanford.edu
Joe Y. Chang, M.D., Ph.D. JYChang@mdanderson.org
Feng-Ming (Spring) Phoenix Kong, M.D., Ph.D. FengKong@umich.edu
Zhongxiang Liao, M.D. zliao@mdanderson.org
 
Normal Tissue EffectsDeborah Citrin, M.D. Citrind@mail.nih.gov
Barry Rosenstein, Ph.D. Barry.Rosenstein@mssm.edu
 
Outcomes / Deborah Citrin, M.D. Citrind@mail.nih.gov
QoL Adam P. Dicker, M.D., Ph.D. adam.dicker@mail.tju.edu
 
ProtonMary Francis McAleer, M.D.mfmcalee@mdanderson.org
 
Publications Arnab Chakravarti, M.D. achakravarti@partners.org
 
SarcomaWilliam Kraybill, M.D. William.Kraybill@RoswellPark.org
David Guy Kirsch, M.D., Ph.D. dKirsch@partners.org
 
Tissue Bank Fred Waldman, MD, PhD. waldman@cc.ucsf.edu
 
Trans-Canada Translational ResearchRobert G. Bristow, M.D., Ph.D. rob.bristow@rmp.uhn.on.ca
Matthew B. Parliament, M.D. matthew.parliament@cancerboard.ab.ca
Peggy L. Olive, Ph.D. polive@bccrc.ca
 

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