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RTOG 0012 Protocol Information

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Randomized Phase II Trial of Preoperative Combined Modality Chemoradiation for Distal Rectal Cancer
Protocol Documents
Current Version Date: 2/25/2003
Principal Investigator: Mohammed Mohiuddin, M.D.
Primary Objective:

To evaluate pathological complete response to preoperative combined modality chemoradiation in cancer of the rectum.

Patient Population:

Adenocarcinoma of the distal rectum located from 0 to 9 cm from the dentate line (3-12 cm from the anal verge) without evidence of distant metastases.
Lesions may be either mobile cancers but stage T3 by endorectal ultrasound, or fixed (defined as clinical T4 for this study) on palpation.

Target Accrual: 100
Current Accrual: 106
Status: Terminated
Date: 6/30/2010
Participating Sites:
21st Century Oncology-Orange Park Orange Park FL
21st Century Oncology-Palatka Palatka FL
Allegiance Health Jackson MI
Baptist Cancer Institute Jacksonville FL
Baptist Medical Center South Jacksonville FL
Bay Area Tumor Institute Oakland CA
Bay Medical Center Panama City FL
Beaumont Hospital - Dearborn Dearborn MI
Cancer Treatment Center Wooster OH
Central Illinois CCOP Decatur IL
Centre Hospitalier de l`Universite de Montreal-Notre Dame Montreal Quebec
Christiana Care Health System-Christiana Hospital Newark DE
Columbia Saint Mary's Water Tower Medical Commons Milwaukee WI
Columbus CCOP Columbus OH
Community Medical Center Toms River NJ
Cottonwood Hospital Medical Center Murray UT
Cross Cancer Institute Edmonton, Alberta
Dayton CCOP Kettering OH
Deaconess Medical Center Spokane WA
Delaware County Memorial Hospital Drexel Hill PA
Dixie Medical Center Regional Cancer Center East St. George UT
Einstein Medical Center Philadelphia Philadelphia PA
Emory University Hospital/Winship Cancer Institute Atlanta GA
Finley Hospital Dubuque IA
Froedtert and the Medical College of Wisconsin Milwaukee WI
Genesys Hurley Cancer Institute Flint MI
Glendale Memorial Hospital and Health Center Glendale CA
Greater Baltimore Medical Center Baltimore MD
Gulf Coast Cancer Treatment Center Panama City FL
Gundersen Lutheran Medical Center La Crosse WI
Hematology Oncology Associates of Central New York-East Syracuse East Syracuse NY
Holy Cross Hospital Fort Lauderdale FL
Huntsman Cancer Institute/University of Utah Salt Lake City UT
Hurley Medical Center Flint MI
Indiana University/Melvin and Bren Simon Cancer Center Indianapolis IN
Ingalls Memorial Hospital Harvey IL
Inspira Medical Center Vineland Vineland NJ
Integrated Community Oncology Network-Flager Cancer Center St Augustine FL
Integrated Community Oncology Network-Florida Cancer Center Beaches Jacksonville Beach FL
Integrated Community Oncology Network-Southside Cancer Center Jacksonville FL
Intermountain Medical Center Murray UT
Johns Hopkins University/Sidney Kimmel Cancer Center Baltimore MD
Jupiter Medical Center Jupiter FL
Kansas City CCOP Prairie Village KS
Lake Huron Medical Center Port Huron MI
Lankenau Medical Center Wynnewood PA
LDS Hospital Salt Lake City UT
Lehigh Valley Hospital-Cedar Crest Allentown PA
Liberty Hospital Liberty MO
Loma Linda University Medical Center Loma Linda CA
London Regional Cancer Program London Ontario
M D Anderson Cancer Center Houston TX
Mainline Health CCOP Wynnewood PA
McKay-Dee Hospital Center Ogden UT
McLaren Cancer Institute-Flint Flint MI
Methodist Hospital Philadelphia PA
Methodist Medical Center of Illinois Peoria IL
Miami Cancer Institute Miami FL
Michigan Cancer Research Consortium Community Clinical Oncology Program Ann Arbor MI
Missouri Valley Cancer Consortium Omaha NE
Mobile Infirmary Medical Center Mobile AL
Moffitt Cancer Center Tampa FL
Monmouth Medical Center Long Branch NJ
Mount Sinai Medical Center Miami Beach FL
Natalie Warren Bryant Cancer Center at Saint Francis Tulsa OK
Naval Medical Center - Portsmouth Portsmouth VA
Nebraska Methodist Hospital Omaha NE
North Star Lodge Cancer Center at Yakima Valley Memorial Hospital Yakima WA
Northern Indiana Cancer Research Consortium South Bend IN
Northwest Community Hospital Arlington Heights IL
Northwestern University Chicago IL
Ochsner Medical Center Jefferson New Orleans LA
Ohio State University Comprehensive Cancer Center Columbus OH
Oncology Institute of Greater Lafayette Lafayette IN
ProHealth Oconomowoc Memorial Hospital Oconomowoc WI
ProHealth Waukesha Memorial Hospital Waukesha WI
Reading Hospital Reading PA
Regional Hospital of Scranton Scranton PA
Richard L. Roudebush VA Medical Center Indianapolis IN
Saint John Hospital and Medical Center Grosse Pointe Woods MI
Saint John Macomb-Oakland Hospital Warren MI
Saint John Medical Center Tulsa OK
Saint Joseph Mercy Hospital Ann Arbor MI
Saint Luke's University Hospital-Bethlehem Campus Bethlehem PA
Saint Mary Mercy Hospital Livonia MI
Saint Mary's of Michigan Saginaw MI
Saint Peter's University Hospital New Brunswick NJ
Sandra L Maxwell Cancer Center Cedar City UT
Sanford Roger Maris Cancer Center Fargo ND
Southeast Cancer Control Consortium CCOP Winston Salem NC
Southwest VA Regional Cancer Center Norton VA
Southwestern Vermont Medical Center Bennington VT
Sparrow Hospital Lansing MI
State University of New York Downstate Medical Center Brooklyn NY
Summa Akron City Hospital/Cooper Cancer Center Akron OH
The James Graham Brown Cancer Center at University of Louisville Louisville KY
Thomas Jefferson University Hospital Philadelphia PA
Trinity Cancer Care Center Minot ND
Tulane University Health Sciences Center New Orleans LA
UCHealth Memorial Hospital Central Colorado Springs CO
UH Seidman Cancer Center at Salem Regional Medical Center Salem OH
University of Florida Health Science Center - Gainesville Gainesville FL
University of Florida Health Science Center - Jacksonville Jacksonville FL
University of Hawaii Cancer Center Honolulu HI
University of Kentucky/Markey Cancer Center Lexington KY
University of Rochester Rochester NY
University of Texas Medical Branch Galveston TX
University of Wisconsin Hospital and Clinics Madison WI
UP Health System Marquette Marquette MI
Utah Cancer Specialists-Salt Lake City Salt Lake City UT
Utah Valley Regional Medical Center Provo UT
Virtua Memorial Mount Holly NJ
Virtua Voorhees Voorhees NJ
Warren Radiation Therapy Center Warren NJ
Wayne Memorial Hospital Goldsboro NC
Wayne Radiation Oncology Goldsboro NC
Wellmont Holston Valley Hospital and Medical Center Kingsport TN
WellSpan Health-York Hospital York PA
West Penn Hospital Pittsburgh PA
William Beaumont Hospital - Troy Troy MI
William Beaumont Hospital-Royal Oak Royal Oak MI
Updated: 4/6/2011

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