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RTOG 0018 Protocol Information

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A Feasibility Study of Neurocognitive Evaluation in Patients Treated for Brain Metastases
Protocol Documents
Current Version Date: 11/13/2000
Principal Investigator: William F. Regine, M.D.
Primary Objective:

To test the feasibility of performing a test battery consisting of five neurocognitive measures and a quality of life instrument in patients with brain metastasis.

Patient Population:

 

  • Histological proof of primary malignancy
  • Brain metastases which are measurable by CT or MRI
  • Zubrod Status 0-1
  • Life expectancy >/=3months
  • Neurological function status of 0-2
  • A certified test administrator is required for administration of neurocognitive assessments
  • No prior RT to the brain
  • No primary site of hematopoietic origin (leukemia) or evidence of leptomeningeal tumor spread
  • No major medical illnesses or psychiatric impairments
  • Signed study-specific consent prior to registration

 

Target Accrual: 50
Current Accrual: 59
Status: Terminated
Date: 12/17/2004
Participating Sites:
Arizona Oncology Services Foundation Scottsdale AZ
Baptist Health Lexington Lexington KY
Cleveland Clinic Foundation Cleveland OH
Columbia Saint Mary's Water Tower Medical Commons Milwaukee WI
Columbus CCOP Columbus OH
Community Memorial Hospital Menomonee Falls WI
Cottonwood Hospital Medical Center Murray UT
Dixie Medical Center Regional Cancer Center East St. George UT
Einstein Medical Center Philadelphia Philadelphia PA
Faxton-Saint Luke's Healthcare Utica NY
Finley Hospital Dubuque IA
Froedtert and the Medical College of Wisconsin Milwaukee WI
Gulf Coast Cancer Treatment Center Panama City FL
Hematology Oncology Associates of Central New York-East Syracuse East Syracuse NY
John F Kennedy Medical Center Edison NJ
Kansas City CCOP Prairie Village KS
LDS Hospital Salt Lake City UT
London Regional Cancer Program London Ontario
Lutheran General Hospital Park Ridge IL
Methodist Cancer Center Omaha NE
Metro-Minnesota CCOP St. Louis Park MN
Montgomery Cancer Center, LLC Montgomery AL
Northern Indiana Cancer Research Consortium South Bend IN
Northwest Community Clinical Oncology Program Tacoma WA
Ohio State University Medical Center Columbus OH
Ozark Health Ventures LLC-Cancer Research for The Ozarks Springfield Springfield MO
Rapid City Regional Hospital Rapid City SD
Southeast Cancer Control Consortium CCOP Winston Salem NC
State University of New York Downstate Medical Center Brooklyn NY
Summa Akron City Hospital/Cooper Cancer Center Akron OH
Tallahassee Memorial HealthCare Tallahassee FL
Thomas Jefferson University Hospital Philadelphia PA
UF Cancer Center at Orlando Health Orlando FL
University of Kentucky/Markey Cancer Center Lexington KY
University of Wisconsin Hospital and Clinics Madison WI
Wayne State University/Karmanos Cancer Institute Detroit MI
Updated: 4/7/2011

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