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RTOG 0023 Protocol Information

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A Phase II Trial of Accelerated Radiotherapy Using Weekly Stereotactic Conformal Boosts for Supratentorial Glioblastoma Multiforme
Protocol Documents
Current Version Date: 3/5/2001
Principal Investigator: Robert M. Cardinale, M.D.
Primary Objective:

Evaluate overall and progression-free survival with an accelerated SRT-Boost treatment schedule

Patient Population:

 

  • Histologically-confirmed supratentorial glioblastoma multiforme
  • Postoperative enhancing tumor plus tumor cavity </= 60 mm
  • Zubrod performance status 0,1
  • Life expectancy > 3 months
  • Hgb > 9 gm, absolute neutrophils > 1500 mm3, platelets > 100, 000
  • BUN < 30, creatinine < 1.8 mg, bilirubin < 2 mg, SGPT or SGOT < twice normal range
  • Therapy must begin within five weeks after surgery
  • Signed study-specific consent form prior to registration
Target Accrual: 76
Current Accrual: 80
Status: Terminated
Date: 2/19/2009
Participating Sites:
Allegheny General Hospital Pittsburgh PA
Arizona Oncology Services Foundation Scottsdale AZ
Cancer Treatment Center Wooster OH
Community Medical Center Toms River NJ
Cottonwood Hospital Medical Center Murray UT
Dixie Medical Center Regional Cancer Center East St. George UT
Einstein Medical Center Philadelphia Philadelphia PA
Froedtert and the Medical College of Wisconsin Milwaukee WI
Froedtert Memorial Lutheran Hospital Milwaukee WI
Gundersen Lutheran Medical Center La Crosse WI
Huntsman Cancer Institute/University of Utah Salt Lake City UT
John B Amos Cancer Center Columbus GA
Kalamazoo CCOP-West Michigan Cancer Center Kalamazoo MI
Kansas City CCOP Prairie Village KS
LDS Hospital Salt Lake City UT
Lehigh Valley Hospital-Cedar Crest Allentown PA
Liberty Hospital Liberty MO
Massachusetts General Hospital Cancer Center Boston MA
McGill University Department of Oncology Montreal
McKay-Dee Hospital Center Ogden UT
Mobile Infirmary Medical Center Mobile AL
Monmouth Medical Center Long Branch NJ
Nevada Cancer Research Foundation CCOP Las Vegas NV
Northwest Community Hospital Arlington Heights IL
Providence Holy Cross Medical Center Mission Hills CA
Rapid City Regional Hospital Rapid City SD
Regional Hospital of Scranton Scranton PA
St Joseph's Hospital Medical Center Stockton CA
Summa Akron City Hospital/Cooper Cancer Center Akron OH
The Research Institute of the McGill University Health Centr Montreal
Thomas Jefferson University Hospital Philadelphia PA
Trinity Cancer Care Center Minot ND
Tulane University Health Sciences Center New Orleans LA
University of California Davis Comprehensive Cancer Center Sacramento CA
University of Cincinnati/Barrett Cancer Center Cincinnati OH
University of Missouri - Ellis Fischel Columbia MO
University of Rochester Rochester NY
University of Texas Medical Branch Galveston TX
University of Wisconsin Hospital and Clinics Madison WI
Utah Valley Regional Medical Center Provo UT
Virginia Commonwealth University/Massey Cancer Center Richmond VA
Virginia Mason CCOP Seattle WA
Virginia Mason Medical Center Seattle WA
Wheeling Hospital/Schiffler Cancer Center Wheeling WV
Yale-New Haven Hospital Saint Raphael Campus New Haven CT
Updated: 4/8/2011

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