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RTOG 0123 Protocol Information

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A Phase II Randomized Trial With Captopril in Patients Who Have Received Radiation Therapy +/ Chemotherapy for Stage II-IIIB Non-Small Cell Lung Cancer or Limited Stage Small Cell Lung Cancer---RTOG CCOP Study
Protocol Documents
Current Version Date: 5/18/2011
Principal Investigator: William Small, Jr., MD
Primary Objective:

Test the ability of captopril to alter the incidence of pulmonary damage at 12 months after treatment in a group of patients at significant risk for pulmonary toxicity

Patient Population:

Stage II-IIIB non-small cell lung cancer or Stage I central NSCLC (excluding peripheral coin lesions) or limited-stage smallcell lung cancer (nonmetastatic disease that is receiving radiotherapy, and the target is confined to a single radiation treatment

Target Accrual: 205
Current Accrual: 81
Status: Terminated
Date: 12/15/2016
Participating Sites:
Adena Regional Medical Center Chillicothe OH
Advocate Good Samaritan Hospital Downers Grove IL
Advocate Good Shepherd Hospital Barrington IL
Advocate Illinois Masonic Medical Center Chicago IL
Advocate Lutheran General Hospital Park Ridge IL
Allegiance Health Jackson MI
Alta Bates Summit Medical Center - Summit Campus Oakland CA
Arizona Oncology Services Foundation Scottsdale AZ
Atlanta Regional CCOP Atlanta GA
Atrium Medical Center-Middletown Regional Hospital Franklin OH
Aurora Saint Luke's Medical Center Milwaukee WI
Baptist Cancer Institute Jacksonville FL
Baptist Health Lexington Lexington KY
Baton Rouge General Medical Center Baton Rouge LA
Bay Area Medical Center Marinette WI
Bay Area Tumor Institute Oakland CA
Beaumont Hospital - Dearborn Dearborn MI
Bixby Medical Center Adrian MI
Blanchard Valley Hospital Findlay OH
Borgess Medical Center Kalamazoo MI
Bronson Methodist Hospital Kalamazoo MI
Bryn Mawr Hospital Bryn Mawr PA
Cape Fear Valley Health System Fayetteville NC
Case Western Reserve University Cleveland OH
Central Maryland Radiation Oncology in Howard County Columbia MD
Champlain Valley Physicians Hospital Medical Center Plattsburgh NY
Christiana Care Health System-Christiana Hospital Newark DE
City of Hope Comprehensive Cancer Center Duarte CA
Columbia Saint Mary's Hospital - Ozaukee Mequon WI
Columbia Saint Mary's Water Tower Medical Commons Milwaukee WI
Columbus CCOP Columbus OH
Community Howard Regional Health Kokomo IN
Community Medical Center Toms River NJ
Community Memorial Hospital Menomonee Falls WI
Cottonwood Hospital Medical Center Murray UT
Cox Medical Center Springfield MO
CoxHealth South Hospital Springfield MO
David Grant United States Air Force Medical Center Travis AFB CA
Dayton CCOP Kettering OH
Delaware County Memorial Hospital Drexel Hill PA
Dixie Medical Center Regional Cancer Center East St. George UT
Doctors Hospital Columbus OH
Doctors Medical Center- JC Robinson Regional Cancer Center San Pablo CA
Duke Women's Cancer Care Raleigh Raleigh NC
East Bay Radiation Oncology Center Castro Valley CA
Einstein Medical Center Philadelphia Philadelphia PA
Elkhart General Hospital Elkhart IN
EvergreenHealth Medical Center Kirkland WA
Finley Hospital Dubuque IA
Firelands Regional Medical Center Sandusky OH
Flower Hospital Sylvania OH
Fox Chase Cancer Center Philadelphia PA
Franciscan Saint Francis Health-Beech Grove Beech Grove IN
Froedtert and the Medical College of Wisconsin Milwaukee WI
Genesys Hurley Cancer Institute Flint MI
Good Samaritan Hospital - Dayton Dayton OH
Grady Memorial Hospital Delaware OH
Grandview Hospital Dayton OH
Grant Medical Center Columbus OH
Green Bay Oncology at Saint Vincent Hospital Green Bay WI
Green Bay Oncology Limited at Saint Mary's Hospital Green Bay WI
Greene Memorial Hospital Xenia OH
Greenville Health System Cancer Institute-Andrews Greenville SC
Greenville Health System Cancer Institute-Eastside Greenville SC
Gulf Coast Cancer Treatment Center Panama City FL
Gundersen Lutheran Medical Center La Crosse WI
Harbin Clinic Rome GA
Helen Denit Cancer Center Olney MD
Hematology Oncology Associates of Central New York-East Syracuse East Syracuse NY
Henry Ford Hospital Detroit MI
Highland Hospital Rochester NY
HSHS Sacred Heart Hospital Eau Claire WI
Huntsman Cancer Institute/University of Utah Salt Lake City UT
Hurley Medical Center Flint MI
Indiana University Health Methodist Hospital Indianapolis IN
Indiana University/Melvin and Bren Simon Cancer Center Indianapolis IN
Inspira Medical Center Vineland Vineland NJ
IU Health La Porte Hospital La Porte IN
Johnson City Medical Center Johnson City TN
Kalamazoo CCOP-West Michigan Cancer Center Kalamazoo MI
Kettering Medical Center Dayton OH
Lakeland Medical Center Saint Joseph St Joseph MI
Lankenau Medical Center Wynnewood PA
LDS Hospital Salt Lake City UT
Legacy Emanuel Hospital and Health Center Portland OR
Legacy Good Samaritan Hospital and Medical Center Portland OR
Legacy Meridian Park Hospital Tualatin OR
Legacy Mount Hood Medical Center Gresham OR
Licking Memorial Hospital Newark OH
Lima Memorial Hospital Lima OH
Louisiana State University Health Science Center New Orleans LA
Mainline Health CCOP Wynnewood PA
Margaret R Pardee Memorial Hospital Hendersonville NC
Marietta Memorial Hospital Marietta OH
Marshfield Clinic Marshfield WI
Marshfield Clinic-Minocqua Center Minocqua WI
Mary Bird Perkins Cancer Center Baton Rouge LA
McKay-Dee Hospital Center Ogden UT
McLaren Cancer Institute-Flint Flint MI
Medical University of Ohio Toledo OH
Memorial Hospital South Bend IN
Mercy Cancer Center-Elyria Elyria OH
Mercy Health System Janesville WI
Mercy Hospital Saint Louis St Louis MO
Mercy Hospital Springfield Springfield MO
Mercy Saint Anne Hospital Toledo OH
Miami Cancer Institute Miami FL
Miami Valley Hospital Dayton OH
Michigan Cancer Research Consortium Community Clinical Oncology Program Ann Arbor MI
Mission Hospital Inc-Memorial Campus Asheville NC
Mobile Infirmary Medical Center Mobile AL
Moffitt Cancer Center Tampa FL
Monmouth Medical Center Long Branch NJ
Mount Carmel Health Center West Columbus OH
Nebraska Methodist Hospital Omaha NE
New York-Presbyterian/Brooklyn Methodist Hospital Brooklyn NY
Newark Beth Israel Medical Center Newark NJ
North Coast Cancer Care Sandusky OH
North Shore-LIJ Health System CCOP Manhasset NY
Northern Indiana Cancer Research Consortium South Bend IN
Northwestern Ontario Regional Cancer Centre Thunder Bay, Ontario
Northwestern University Chicago IL
Novant Health Presbyterian Medical Center Charlotte NC
Ozark Health Ventures LLC-Cancer Research for The Ozarks Springfield Springfield MO
Paoli Memorial Hospital Paoli PA
PeaceHealth Southwest Medical Center Vancouver WA
Piedmont Hospital Atlanta GA
Pomona Valley Hospital Medical Center Pomona CA
Providence Milwaukie Hospital Milwaukie OR
Providence Portland Medical Center Portland OR
Providence Saint Joseph Medical Center/Disney Family Cancer Center Burbank CA
Providence Saint Joseph Medical Center/Disney Family Cancer Center Burbank CA
Providence Saint Vincent Medical Center Portland OR
Providence St. Joseph Medical Center - Disney Family CA Ctr Burbank CA
Queen's Medical Center Honolulu HI
Rapid City Regional Hospital Rapid City SD
Rex Cancer Center Raleigh NC
Rex Cancer Center Raleigh NC
Richard L. Roudebush VA Medical Center Indianapolis IN
Riverside Methodist Hospital Columbus OH
Roswell Park Cancer Institute Buffalo NY
Saint Ann's Hospital Westerville OH
Saint Charles Hospital Oregon OH
Saint Francis Hospital Federal Way WA
Saint John Hospital and Medical Center Grosse Pointe Woods MI
Saint John Macomb-Oakland Hospital Warren MI
Saint Joseph Mercy Hospital Ann Arbor MI
Saint Joseph Regional Medical Center South Bend In
Saint Joseph Regional Medical Center-Mishawaka Mishawaka IN
Saint Luke's University Hospital-Bethlehem Campus Bethlehem PA
Saint Mary's of Michigan Saginaw MI
Saint Vincent Anderson Regional Hospital/Cancer Center Anderson IN
Saint Vincent Hospital Cancer Center Green Bay Green Bay WI
Saint Vincent Mercy Medical Center Toledo OH
Santa Monica Cancer Treatment Center Inglewood CA
Sarasota Radiation & Medical Oncology Center Sarasota FL
Scott and White Memorial Hospital Temple TX
Singing River Hospital Pascagoula MS
Southeast Cancer Control Consortium CCOP Winston Salem NC
Southeast Missouri Hospital Cape Girardeau MO
Sparrow Hospital Lansing MI
Springfield Regional Medical Center Springfield OH
St. Anthony's Health Alton IL
State University of New York Downstate Medical Center Brooklyn NY
The Cancer Center for Southern Kentucky Bowling Green KY
The Cancer Center of Hawaii-Liliha Honolulu HI
The Ireland Cancer Center at Community Health Partners Elyria OH
The James Graham Brown Cancer Center at University of Louisville Louisville KY
The Toledo Hospital/Toledo Children's Hospital Toledo OH
Toledo Clinic Cancer Centers-Adrian Adrian MI
Toledo Clinic Cancer Centers-Maumee Maumee OH
Toledo Community Hospital Oncology Program CCOP Toledo OH
Tom Baker Cancer Centre Calgary, Alberta
Trinity Cancer Care Center Minot ND
UCHealth Memorial Hospital Central Colorado Springs CO
UHHS-Chagrin Highlands Medical Center Orange Village OH
UHHS-Westlake Medical Center Westlake OH
Union Hospital Terre Haute IN
University of Alabama at Birmingham Cancer Center Birmingham AL
University of Colorado Hospital Aurora CO
University of Florida Health Science Center - Gainesville Gainesville FL
University of Florida Health Science Center - Jacksonville Jacksonville FL
University of Hawaii Cancer Center Honolulu HI
University of Maryland/Greenebaum Cancer Center Baltimore MD
University of Miami Miller School of Medicine-Sylvester Cancer Center Miami FL
University of Missouri - Ellis Fischel Columbia MO
University of Rochester Rochester NY
UPMC-Mercy Hospital Pittsburgh PA
Upper Valley Medical Center Troy OH
Utah Valley Regional Medical Center Provo UT
Valley Medical Oncology Consultants Pleasanton CA
Veteran Affairs Medical Center Dayton OH
Veterans Administration Long Beach Medical Center Long Beach CA
Virginia Mason CCOP Seattle WA
Virginia Mason Medical Center Seattle WA
Virtua Memorial Mount Holly NJ
Washington University School of Medicine St. Louis MO
Wayne Memorial Hospital Goldsboro NC
Wayne Radiation Oncology Goldsboro NC
West Allis Memorial Hospital West Allis WI
Western Oncology Research Consortium Portland OR
Wheaton Franciscan Cancer Care-All Saints Racine WI
William Beaumont Hospital-Royal Oak Royal Oak MI
Wilmed Radiation Oncology Services Wilson NC
Updated: 12/15/2016

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