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RTOG 0211 Protocol Information

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A Phase I/II Study of an Oral Epidermal Growth Factor Receptor Tyrosine-Kinase Inhibitor (EGFR-TKI), ZD 1839 (IRESSA) [NSC# 715055] with Radiation Therapy in Glioblastoma Multiforme
Protocol Documents
Current Version Date: 3/24/2010
Principal Investigator: Arnab Chakravarti, M.D.
Primary Objective:

To identify the maximum tolerated dose of ZD 1839 when given concurrently with cranial radiotherapy

Patient Population:

Histopathologically confirmed glioblastoma multiforme (with areas of necrosis) The tumor must be supratentorial in location

Target Accrual: 140-158
Current Accrual: 178
Status: Terminated
Date: 11/5/2013
Participating Sites:
21st Century Oncology Ft. Myers FL
Abington Memorial Hospital Abington PA
Allan Blair Cancer Centre Regina, SK
Allegheny General Hospital Pittsburgh PA
Allegheny Valley Hospital Natrona Heights PA
Alta Bates Summit Medical Center-Herrick Campus Berkeley CA
AMITA Health Alexian Brothers Medical Center Elk Grove Village IL
Arizona Oncology Services Foundation Scottsdale AZ
Atlanta Regional CCOP Atlanta GA
AtlantiCare Regional Medical Center Pomona NJ
Baptist Cancer Institute Jacksonville FL
Bay Area Tumor Institute Oakland CA
California Pacific Medical Center-Pacific Campus San Francisco CA
Cancer Treatment Center Wooster OH
Cape Radiation Oncology Cape Girardeau MO
Caritas Regional Cancer Center Louisville KY
Case Western Reserve University Cleveland OH
Centre Hospitalier de l`Universite de Montreal-Notre Dame Montreal Quebec
Christiana Care Health System-Christiana Hospital Newark DE
CHUM - Centre Hospitalier de l'Universite de Montreal Montreal
Cleveland Clinic Akron General Akron OH
Community Memorial Hospital Menomonee Falls WI
Cottonwood Hospital Medical Center Murray UT
Covenant Medical Center-Lakeside Lubbock TX
Cross Cancer Institute Edmonton, Alberta
Delaware County Memorial Hospital Drexel Hill PA
Dixie Medical Center Regional Cancer Center East St. George UT
East Bay Radiation Oncology Center Castro Valley CA
Finley Hospital Dubuque IA
Fox Chase Cancer Center Philadelphia PA
Froedtert and the Medical College of Wisconsin Milwaukee WI
Gulf Coast Cancer Treatment Center Panama City FL
Gundersen Lutheran Medical Center La Crosse WI
Harbin Clinic Rome GA
Holy Cross Hospital Fort Lauderdale FL
Ingalls Memorial Hospital Harvey IL
Inspira Medical Center Vineland Vineland NJ
Intercommunity Cancer Center Monroeville PA
Intermountain Medical Center Murray UT
Jackson-Madison County General Hospital Jackson TN
Juravinski Cancer Centre at Hamilton Health Sciences Hamilton, Ontario
Kalamazoo CCOP-West Michigan Cancer Center Kalamazoo MI
Kansas City CCOP Prairie Village KS
Kentucky Clinic Berea Berea KY
Lake University Ireland Cancer Center Mentor OH
Lankenau Medical Center Wynnewood PA
LDS Hospital Salt Lake City UT
Lehigh Valley Hospital-Cedar Crest Allentown PA
Liberty Hospital Liberty MO
London Regional Cancer Program London Ontario
Louisiana State University Health Science Center New Orleans LA
Mainline Health CCOP Wynnewood PA
Marshfield Clinic Marshfield WI
Mary Bird Perkins Cancer Center Baton Rouge LA
Massachusetts General Hospital Cancer Center Boston MA
Mayo Clinic Rochester MN
McGill University Department of Oncology Montreal
McKay-Dee Hospital Center Ogden UT
Metro-Minnesota CCOP St. Louis Park MN
Mills-Peninsula Medical Center San Mateo CA
Missouri Valley Cancer Consortium Omaha NE
Mobile Infirmary Medical Center Mobile AL
Moffitt Cancer Center Tampa FL
Monmouth Medical Center Long Branch NJ
Mount Sinai Medical Center Miami Beach FL
Natalie Warren Bryant Cancer Center at Saint Francis Tulsa OK
Nebraska Methodist Hospital Omaha NE
North Star Lodge Cancer Center at Yakima Valley Memorial Hospital Yakima WA
Northwest Community Hospital Arlington Heights IL
Ochsner Medical Center Jefferson New Orleans LA
Penn State Milton S Hershey Medical Center Hershey PA
Pocono Medical Center East Strousburg PA
Pomona Valley Hospital Medical Center Pomona CA
Radiological Associates of Sacramento Sacramento CA
Rapid City Regional Hospital Rapid City SD
Regional Hospital of Scranton Scranton PA
Roswell Park Cancer Institute Buffalo NY
Saint Agnes Medical Center Fresno CA
Saint Alphonsus Cancer Care Center-Boise Boise ID
Saint Claire Regional Medical Center Morehead KY
Saint Francis Medical Center Cape Girardeau MO
Saint Francis Medical Center Trenton NJ
Saint John Medical Center Tulsa OK
Saint Vincent Hospital Cancer Center Green Bay Green Bay WI
Sandra L Maxwell Cancer Center Cedar City UT
Southeast Cancer Control Consortium CCOP Winston Salem NC
Southern Wisconsin Radiotherapy Center Madison WI
Summa Akron City Hospital/Cooper Cancer Center Akron OH
Sutter Health Western Division Cancer Research Group Novato CA
The Research Institute of the McGill University Health Centr Montreal
Thomas Jefferson University Hospital Philadelphia PA
Trinity's Tony Teramana Cancer Center Steubenville OH
UCHealth Memorial Hospital Central Colorado Springs CO
UH Seidman Cancer Center at Salem Regional Medical Center Salem OH
UHHS-Chagrin Highlands Medical Center Orange Village OH
UHHS-Westlake Medical Center Westlake OH
Union Hospital Terre Haute IN
United Hospital St. Paul MN
University of California Davis Comprehensive Cancer Center Sacramento CA
University of Colorado Hospital Aurora CO
University of Florida Health Science Center - Gainesville Gainesville FL
University of Florida Health Science Center - Jacksonville Jacksonville FL
University of Kentucky/Markey Cancer Center Lexington KY
University of Miami Miller School of Medicine-Sylvester Cancer Center Miami FL
University of Rochester Rochester NY
University of Virginia Cancer Center Charlottesville VA
University of Washington Medical Center Seattle WA
University of Wisconsin Hospital and Clinics Madison WI
UPMC-Mercy Hospital Pittsburgh PA
UPMC-Presbyterian Hospital Pittsburgh PA
Upstate Carolina CCOP Spartanburg SC
Utah Cancer Specialists-Salt Lake City Salt Lake City UT
Utah Valley Regional Medical Center Provo UT
Valley Medical Oncology Consultants Pleasanton CA
Veteran's Administration Medical Center - Lexington Lexington KY
WellSpan Health-York Hospital York PA
West Penn Hospital Pittsburgh PA
Wheaton Franciscan Cancer Care-All Saints Racine WI
Wheeling Hospital/Schiffler Cancer Center Wheeling WV
Yale University New Haven CT
Updated: 11/8/2013

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