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RTOG 0212 Protocol Information

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A Phase II/III Randomized Trial of Two Dose Schedules for Delivering Prophylactic Cranial Irradiation for Patients with Limited Disease Small Cell Lung Cancer (Companion Study to the International Cranial Irradiation Trial, PCI 01EULINT1)
Protocol Documents
Current Version Date: 3/24/2010
Principal Investigator: Aaron H. Wolfson, M.D.
Primary Objective:

To determine the impact of PCI dose and schedule on the incidence of chronic neurotoxicity To determine the impact of PCI dose and schedule on quality of life.

Patient Population:

Histologic proof or unequivocal cytologic proof of SCLC Limited disease SCLC, clinical stages I-IIIB (AJCC, 1997), whatever the induction treatment

Target Accrual: 264
Current Accrual: 265
Status: Terminated
Date: 11/5/2013
Participating Sites:
21st Century Oncology Ft. Myers FL
21st Century Oncology Inc-Broadway Fort Myers FL
Abington Memorial Hospital Abington PA
Adventist Medical Center Portland OR
Allegiance Health Jackson MI
Alta Bates Summit Medical Center - Summit Campus Oakland CA
AMITA Health Adventist Medical Center LaGrange IL
AnMed Health Cancer Center Anderson SC
Anne Arundel Medical Center Annapolis MD
Aria Health Philadelphia PA
Arizona Oncology Services Foundation Scottsdale AZ
Arlington Cancer Center Arlington TX
Asante Health System Medford OR
Asante Rogue Regional Medical Center Medford OR
Asante Three Rivers Medical Center Grants Pass OR
AtlantiCare Regional Medical Center Pomona NJ
Aultman Health Foundation Canton OH
Bay Area Medical Center Marinette WI
Bay Area Tumor Institute Oakland CA
Bay Medical Center Panama City FL
Bixby Medical Center Adrian MI
Blanchard Valley Hospital Findlay OH
Bon Secours Saint Mary's Hospital Richmond VA
Borgess Medical Center Kalamazoo MI
Boston Medical Center Boston MA
Bronson Methodist Hospital Kalamazoo MI
Butterworth Hospital Grand Rapids MI
Cancer Care Manitoba Foundation Winnipeg, Manitoba
Cancer Treatment Center Wooster OH
Cape Fear Valley Health System Fayetteville NC
Cape Radiation Oncology Cape Girardeau MO
Carle Cancer Center Urbana IL
Case Western Reserve University Cleveland OH
Central Maryland Radiation Oncology in Howard County Columbia MD
Centre Hospitalier de l`Universite de Montreal-Notre Dame Montreal Quebec
Champlain Valley Physicians Hospital Medical Center Plattsburgh NY
Cherry Tree Cancer Center Hanover PA
Cheshire Medical Center-Dartmouth-Hitchcock Keene Keene NH
Christiana Care Health System-Christiana Hospital Newark DE
CHU de Quebec-L'Hotel-Dieu de Quebec (HDQ) Quebec
CHUM - Centre Hospitalier de l'Universite de Montreal Montreal
CIUSSSEMTL-Hopital Maisonneuve-Rosemont Montreal, Quebec
CJW Medical Center - Johnston-Willis Campus Richmond VA
Cleveland Clinic Cancer Center-Independence Independence OH
Cleveland Clinic Foundation Cleveland OH
Coborn Cancer Center at Saint Cloud Hospital St. Cloud MN
Community Cancer Center Foundation Normal IL
Community Howard Regional Health Kokomo IN
Community Medical Center Toms River NJ
Community Memorial Hospital Menomonee Falls WI
Cooper Hospital University Medical Center Camden NJ
Cottonwood Hospital Medical Center Murray UT
CoxHealth South Hospital Springfield MO
Danville Regional Medical Center Danville VA
Dartmouth-Hitchcock Medical Center/Norris Cotton Cancer Center Lebanon NH
Delaware County Memorial Hospital Drexel Hill PA
Dixie Medical Center Regional Cancer Center East St. George UT
Doctors Medical Center- JC Robinson Regional Cancer Center San Pablo CA
Duke Women's Cancer Care Raleigh Raleigh NC
East Carolina University Greenville NC
East Bay Radiation Oncology Center Castro Valley CA
Einstein Medical Center Philadelphia Philadelphia PA
Elkhart General Hospital Elkhart IN
Emory University Hospital/Winship Cancer Institute Atlanta GA
Finley Hospital Dubuque IA
Firelands Regional Medical Center Sandusky OH
Flower Hospital Sylvania OH
Fox Chase Cancer Center Philadelphia PA
Franciscan St. James Health-Olympia Fields Campus Olympia Fields IL
Froedtert and the Medical College of Wisconsin Milwaukee WI
Geisinger Medical Center Danville PA
Geisinger Wyoming Valley/Henry Cancer Center Wilkes Barre PA
Grand Rapids Clinical Oncology Program Grand Rapids MI
Green Bay Oncology at Saint Vincent Hospital Green Bay WI
Green Bay Oncology Limited at Saint Mary's Hospital Green Bay WI
Greenville Health System Cancer Institute-Andrews Greenville SC
Greenville Health System Cancer Institute-Eastside Greenville SC
Gulf Coast Cancer Treatment Center Panama City FL
Gundersen Lutheran Medical Center La Crosse WI
Harrison Medical Center Bremerton WA
Helen Denit Cancer Center Olney MD
Hematology Oncology Associates of Central New York-East Syracuse East Syracuse NY
Henry Ford Hospital Detroit MI
Highland Hospital Rochester NY
Hillcrest Hospital Cancer Center Mayfield Heights OH
Hines Veterans Administration Hospital Hines IL
Hudson Valley Oncology Associates Poughkeepsie NY
Huntsman Cancer Institute/University of Utah Salt Lake City UT
Illinois CancerCare-Peoria Peoria IL
Indiana University Health Ball Memorial Hospital, Inc. Muncie IN
Indiana University/Melvin and Bren Simon Cancer Center Indianapolis IN
Ingalls Memorial Hospital Harvey IL
Inspira Medical Center Vineland Vineland NJ
Integris Cancer Institute of Oklahoma Oklahoma City OK
Intermountain Medical Center Murray UT
Iredell Memorial Hospital Statesville NC
IU Health La Porte Hospital La Porte IN
John F Kennedy Medical Center Edison NJ
John Muir Medical Center-Concord Concord CA
John Muir Medical Center-Walnut Creek Concord CA
Kalamazoo CCOP-West Michigan Cancer Center Kalamazoo MI
Kansas City CCOP Prairie Village KS
Lakeland Medical Center Saint Joseph St Joseph MI
Lakeland Regional Health System St. Joseph MI
LDS Hospital Salt Lake City UT
Legacy Emanuel Hospital and Health Center Portland OR
Legacy Good Samaritan Hospital and Medical Center Portland OR
Legacy Meridian Park Hospital Tualatin OR
Legacy Mount Hood Medical Center Gresham OR
Lexington Clinic Cancer Center Lexington KY
Liberty Hospital Liberty MO
Lima Memorial Hospital Lima OH
London Regional Cancer Program London Ontario
Loyola University Medical Center Maywood IL
M D Anderson Cancer Center Houston TX
Mayo Clinic Health Systems-Mankato Mankato MN
McGill University Department of Oncology Montreal
McKay-Dee Hospital Center Ogden UT
McLaren Northern Michigan Petoskey MI
Medical University of Ohio Toledo OH
Medical University of South Carolina Charleston SC
MedStar Georgetown University Hospital Washington DC
Memorial Hospital South Bend IN
Memorial Sloan Kettering Cancer Center New York NY
Mercy Cancer Center-Elyria Elyria OH
Mercy General Radiation Oncology Center Sacramento CA
Mercy Health Saint Mary's Grand Rapids MI
Mercy Hospital Saint Louis St Louis MO
Mercy Hospital Springfield Springfield MO
Mercy Saint Anne Hospital Toledo OH
Mercy San Juan Medical Center Carmichael CA
Methodist Hospital Philadelphia PA
Methodist Medical Center of Illinois Peoria IL
Miami Cancer Institute Miami FL
Mobile Infirmary Medical Center Mobile AL
Monmouth Medical Center Long Branch NJ
Munson Medical Center Traverse City MI
Nebraska Methodist Hospital Omaha NE
Nevada Cancer Research Foundation CCOP Las Vegas NV
New York-Presbyterian/Brooklyn Methodist Hospital Brooklyn NY
Norris Cotton Cancer Center-North Saint Johnsbury VT
North Coast Cancer Care Sandusky OH
Northeast Georgia Medical Center-Gainesville Gainesville GA
Northeast Radiation Oncology Center Dunmore PA
Northern Indiana Cancer Research Consortium South Bend IN
Northridge Hospital Medical Center Northridge CA
Northwest Community Hospital Arlington Heights IL
Northwestern Ontario Regional Cancer Centre Thunder Bay, Ontario
Northwestern University Chicago IL
Novant Health Presbyterian Medical Center Charlotte NC
Ocean Medical Center Brick NJ
Ohio State University Comprehensive Cancer Center Columbus OH
Orange Regional Medical Center Middletown NY
Oregon Health and Science University Portland OR
OSF Saint Francis Medical Center Peoria IL
OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center Pekin IL
OSF Saint Francis Radiation Oncology at Peoria Cancer Center Peoria IL
Ozark Health Ventures LLC-Cancer Research for The Ozarks Springfield Springfield MO
Parkview Hospital Randallia Fort Wayne IN
PeaceHealth Saint Joseph Medical Center Bellingham WA
PeaceHealth Southwest Medical Center Vancouver WA
Peninsula Regional Medical Center Salisbury MD
Penn State Milton S Hershey Medical Center Hershey PA
Penrose-Saint Francis Healthcare Colorado Springs CO
Pocono Medical Center East Strousburg PA
Pomona Valley Hospital Medical Center Pomona CA
ProHealth Oconomowoc Memorial Hospital Oconomowoc WI
ProHealth Waukesha Memorial Hospital Waukesha WI
Providence Medford Medical Center Medford OR
Providence Milwaukie Hospital Milwaukie OR
Providence Portland Medical Center Portland OR
Providence Saint Vincent Medical Center Portland OR
Providence St. Joseph Medical Center - Disney Family CA Ctr Burbank CA
QEII Health Sciences Centre/Nova Scotia Health Authority Halifax, Nova Scotia
Radiation Oncology Associates Reno NV
Radiation Oncology Associates PC Fort Wayne IN
Radiation Oncology Center Alliance OH
Radiological Associates of Sacramento Sacramento CA
Rapid City Regional Hospital Rapid City SD
Reading Hospital Reading PA
Renown Regional Medical Center Reno NV
Rex Cancer Center Raleigh NC
Richard L. Roudebush VA Medical Center Indianapolis IN
Riverview Medical Center/Booker Cancer Center Red Bank NJ
Roswell Park Cancer Institute Buffalo NY
Rush University Medical Center Chicago IL
Rush-Copley Medical Center Aurora IL
Rutherford Hospital Rutherfordton NC
Saint Agnes Medical Center Fresno CA
Saint Charles Hospital Oregon OH
Saint Francis Medical Center Cape Girardeau MO
Saint John Hospital and Medical Center Grosse Pointe Woods MI
Saint Joseph Regional Medical Center South Bend In
Saint Joseph Regional Medical Center-Mishawaka Mishawaka IN
Saint Luke's University Hospital-Bethlehem Campus Bethlehem PA
Saint Mary's Hospital and Regional Medical Center Grand Junction CO
Saint Rita's Medical Center Lima OH
Saint Vincent Anderson Regional Hospital/Cancer Center Anderson IN
Saint Vincent Hospital Cancer Center at Saint Mary's Green Bay WI
Saint Vincent Hospital Cancer Center Green Bay Green Bay WI
Saint Vincent Mercy Medical Center Toledo OH
Sandra L Maxwell Cancer Center Cedar City UT
Santa Rosa Memorial Hospital CCOP Santa Rosa CA
Sarasota Radiation & Medical Oncology Center Sarasota FL
Scott and White Memorial Hospital Temple TX
Scottsdale Radiation Oncology Centers-Osborn Center Scottsdale AZ
Scottsdale Radiation Oncology Centers-Shea Center Scottsdale AZ
Singing River Hospital Pascagoula MS
Siteman Cancer Center at Saint Peters Hospital St. Peters MO
South Suburban Oncology Center Quincy MA
Southeast Cancer Control Consortium CCOP Winston Salem NC
Southeast Missouri Hospital Cape Girardeau MO
Sparrow Hospital Lansing MI
Sparta Cancer Center Sparta NJ
Spartanburg Medical Center Spartanburg SC
St Anne's Hospital Fall River MA
St Joseph Hospital Mishawaka IN
St Joseph's Hospital Medical Center Stockton CA
St Luke's Hospital Chesterfield MO
St. Anthony Cancer Care Institute at St. Anthony Hospital Oklahoma City OK
St. Anthony's Health Alton IL
State University of New York Upstate Medical University Syracuse NY
Summa Akron City Hospital/Cooper Cancer Center Akron OH
Sutter Cancer Centers Radiation Oncology Services-Auburn Auburn CA
Sutter Cancer Centers Radiation Oncology Services-Cameron Park Cameron Park CA
Sutter Cancer Centers Radiation Oncology Services-Roseville Roseville CA
Sutter Cancer Centers Radiation Oncology Services-Vacaville Vacaville CA
Sutter Medical Center Sacramento Sacramento CA
Temple University Hospital Philadelphia PA
The Christ Hospital Cincinnati OH
The Ireland Cancer Center at Community Health Partners Elyria OH
The Regional Cancer Center Erie PA
The Research Institute of the McGill University Health Centr Montreal
The Reverend Roger Patrick Dorcy Cancer Center Pueblo CO
The Toledo Hospital/Toledo Children's Hospital Toledo OH
Thomas Jefferson University Hospital Philadelphia PA
Toledo Clinic Cancer Centers-Adrian Adrian MI
Toledo Clinic Cancer Centers-Maumee Maumee OH
Toledo Community Hospital Oncology Program CCOP Toledo OH
Tom Baker Cancer Centre Calgary, Alberta
Torrance Memorial Medical Center Torrance CA
Trinity Cancer Care Center Minot ND
UC San Diego Moores Cancer Center LaJolla CA
UCHealth Memorial Hospital Central Colorado Springs CO
UH Seidman Cancer Center at Salem Regional Medical Center Salem OH
Union Hospital Terre Haute IN
University Health Network-Princess Margaret Hospital Toronto, Ontario
University Medical Center of Princeton at Plainsboro Princeton NJ
University of Alabama at Birmingham Cancer Center Birmingham AL
University of Arkansas for Medical Sciences Little Rock AR
University of California Davis Comprehensive Cancer Center Sacramento CA
University of Chicago Comprehensive Cancer Center Chicago IL
University of Cincinnati/Barrett Cancer Center Cincinnati OH
University of Colorado Hospital Aurora CO
University of Florida Health Science Center - Gainesville Gainesville FL
University of Florida Health Science Center - Jacksonville Jacksonville FL
University of Iowa/Holden Comprehensive Cancer Center Iowa City IA
University of Kentucky/Markey Cancer Center Lexington KY
University of Maryland/Greenebaum Cancer Center Baltimore MD
University of Miami Miller School of Medicine-Sylvester Cancer Center Miami FL
University of Michigan Comprehensive Cancer Center Ann Arbor MI
University of Minnesota/Masonic Cancer Center Minneapolis MN
University of Missouri - Ellis Fischel Columbia MO
University of Rochester Rochester NY
University of Southwestern Moncrief Cancer Ctr-Fort Worth Fort Worth TX
University of Texas Southwestern Medical School Dallas TX
University of Washington Medical Center Seattle WA
University of Wisconsin Hospital and Clinics Madison WI
University Pointe West Chester OH
UPMC-Mercy Hospital Pittsburgh PA
Upstate Carolina CCOP Spartanburg SC
UT Southwestern/Simmons Cancer Center-Dallas Dallas TX
Utah Cancer Specialists-Salt Lake City Salt Lake City UT
Utah Valley Regional Medical Center Provo UT
Valley Medical Oncology Consultants Pleasanton CA
Vanderbilt University/Ingram Cancer Center Nashville TN
Veteran's Administration Medical Center - Ann Arbor Ann Arbor MI
Virginia Mason CCOP Seattle WA
Virtua Memorial Mount Holly NJ
Washington Cancer Institute Washington DC
Washington University School of Medicine St. Louis MO
Wayne Memorial Hospital Goldsboro NC
Wayne Radiation Oncology Goldsboro NC
Wayne State University/Karmanos Cancer Institute Detroit MI
WellSpan Health-York Hospital York PA
Wenatchee Valley Hospital and Clinics Wenatchee WA
Wesley Medical Center Wichita KS
West Penn Hospital Pittsburgh PA
Western Oncology Research Consortium Portland OR
Wheaton Franciscan Cancer Care-All Saints Racine WI
Wheeling Hospital/Schiffler Cancer Center Wheeling WV
Wichita CCOP Wichita KS
William Beaumont Hospital-Royal Oak Royal Oak MI
Wilmed Radiation Oncology Services Wilson NC
Yale University New Haven CT
Zablocki VA Medical Center-Wood Milwaukee WI
Updated: 11/6/2013

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