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RTOG 0229 Protocol Information

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A Phase II Trial of Neoadjuvant Therapy with Concurrent Chemotherapy and High Dose Radiotherapy Followed by Surgical Resection and Consolidative Therapy for Locally Advanced Non-Small Cell Lung Carcinoma
Protocol Documents
Current Version Date: 5/18/2011
Principal Investigator: Mohan Suntharalingam, M.D.
Primary Objective:

To estimate the mediastinal nodal clearance rates with the pre-operative regimen and the rate of complete pathological response after treatment with pre-operative chemotherapy with paclitaxel/carboplatin and high dose radiation for stage III NSCLC

Patient Population:

Patients with Stage IIIA (T1-3 N2) or Stage IIIB (N3, excluding supraclavicular involvement) non-small cell lung cancer documented by biopsy or cytology (Pancoast tumors are eligible if pathologic evidence of mediastinal nodal disease is present). Patients must have a serum albumin of >= 3.0 g/dL.

Target Accrual: 60
Current Accrual: 60
Status: Terminated
Date: 5/16/2016
Participating Sites:
Allegiance Health Jackson MI
Annie Penn Memorial Hospital Reidsville NC
Arizona Oncology Services Foundation Scottsdale AZ
Atrium Medical Center-Middletown Regional Hospital Franklin OH
Baptist Cancer Institute Jacksonville FL
Bay Area Medical Center Marinette WI
Beaumont Hospital - Dearborn Dearborn MI
Blanchard Valley Hospital Findlay OH
Boston Medical Center MBCCOP Boston MA
Bryn Mawr Hospital Bryn Mawr PA
Cape Radiation Oncology Cape Girardeau MO
Central Maryland Radiation Oncology in Howard County Columbia MD
City of Hope Comprehensive Cancer Center Duarte CA
Cleveland Clinic Cancer Center/Fairview Hospital Cleveland OH
Cleveland Clinic Cancer Center-Independence Independence OH
Cleveland Clinic Foundation Cleveland OH
Cone Health Cancer Center Greensboro NC
Cooper Health System-Voorhees Voorhees NJ
Cooper Hospital University Medical Center Camden NJ
CoxHealth South Hospital Springfield MO
Dayton CCOP Kettering OH
East Carolina University Greenville NC
Franciscan Saint Francis Health-Beech Grove Beech Grove IN
Franciscan St. James Health-Olympia Fields Campus Olympia Fields IL
Franciscan St. Margaret Health Hammond IN
Froedtert and the Medical College of Wisconsin Milwaukee WI
Genesys Hurley Cancer Institute Flint MI
Good Samaritan Hospital - Dayton Dayton OH
Grandview Hospital Dayton OH
Green Bay Oncology at Saint Vincent Hospital Green Bay WI
Green Bay Oncology Limited at Saint Mary's Hospital Green Bay WI
Greene Memorial Hospital Xenia OH
Gulf Coast Cancer Treatment Center Panama City FL
Gundersen Lutheran Medical Center La Crosse WI
Guthrie Medical Group PC-Robert Packer Hospital Sayre PA
Helen Denit Cancer Center Olney MD
Hematology Oncology Associates of Central New York-East Syracuse East Syracuse NY
Hurley Medical Center Flint MI
Kettering Medical Center Dayton OH
Lake Huron Medical Center Port Huron MI
Lankenau Medical Center Wynnewood PA
Lehigh Valley Hospital-Cedar Crest Allentown PA
Los Angeles County-USC Medical Center Los Angeles CA
Mainline Health CCOP Wynnewood PA
Mayo Clinic Rochester MN
Mayo Clinic in Florida Jacksonville FL
McLaren Cancer Institute - Flint Flint MI
Medical University of South Carolina Charleston SC
Mercy Health System Janesville WI
Mercy Hospital Springfield Springfield MO
Methodist Cancer Center Omaha NE
Miami Valley Hospital Dayton OH
Michigan Cancer Research Consortium Community Clinical Oncology Program Ann Arbor MI
Northeast Georgia Medical Center-Gainesville Gainesville GA
Norton Suburban Hospital and Medical Campus Louisville KY
Ocean Medical Center Brick NJ
Ozark Health Ventures LLC-Cancer Research for The Ozarks Springfield Springfield MO
Paoli Memorial Hospital Paoli PA
Randolph Hospital Ashboro NC
Rapid City Regional Hospital Rapid City SD
Reid Health Richmond IN
Saint Alphonsus Cancer Care Center-Boise Boise ID
Saint John Hospital and Medical Center Grosse Pointe Woods MI
Saint John Macomb-Oakland Hospital Warren MI
Saint Joseph Mercy Hospital Ann Arbor MI
Saint Joseph Mercy Oakland Pontac MI
Saint Luke's University Hospital-Bethlehem Campus Bethlehem PA
Saint Mary Mercy Hospital Livonia MI
Saint Mary's of Michigan Saginaw MI
Saint Vincent Hospital Cancer Center at Saint Mary's Green Bay WI
Saint Vincent Hospital Cancer Center Green Bay Green Bay WI
Santa Monica Cancer Treatment Center Inglewood CA
Scottsdale Radiation Oncology Centers-Osborn Center Scottsdale AZ
Scottsdale Radiation Oncology Centers-Shea Center Scottsdale AZ
Siteman Cancer Center at Saint Peters Hospital St. Peters MO
Siteman Cancer Center at West County Hospital St. Louis MO
Smilow Cancer Hospital Care Center at Saint Francis Hartford CT
Southwest VA Regional Cancer Center Norton VA
Sparrow Hospital Lansing MI
St Johns Hospital, Cancer Institute Springfield IL
State University of New York Downstate Medical Center Brooklyn NY
Summa Akron City Hospital/Cooper Cancer Center Akron OH
Tallahassee Memorial HealthCare Tallahassee FL
The Cancer Center for Southern Kentucky Bowling Green KY
The Kirklin Clinic at Acton Road Birmingham AL
Tom Baker Cancer Centre Calgary, Alberta
University Hospital of Brooklyn at Long Island College Hospital Brooklyn NY
University of Alabama at Birmingham Cancer Center Birmingham AL
University of Florida Health Science Center - Gainesville Gainesville FL
University of Florida Health Science Center - Jacksonville Jacksonville FL
University of Maryland/Greenebaum Cancer Center Baltimore MD
University of Southern California Los Angeles CA
Upper Valley Medical Center Troy OH
Veteran Affairs Medical Center Dayton OH
Virtua Memorial Mount Holly NJ
Washington University School of Medicine St. Louis MO
Wayne State University/Karmanos Cancer Institute Detroit MI
Wellmont Holston Valley Hospital and Medical Center Kingsport TN
West Penn Hospital Pittsburgh PA
Wheeling Hospital/Schiffler Cancer Center Wheeling WV
Wright-Patterson Medical Center Wright-Patterson AFB OH
Yale University New Haven CT
Zablocki VA Medical Center-Wood Milwaukee WI
Updated: 5/16/2016

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