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RTOG 0236 Protocol Information

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A Phase II Trial of Stereotactic Body Radiation Therapy (SBRT) in the Treatment of Patients with Medically Inoperable Stage I/II Non-Small Cell Lung Cancer
Protocol Documents
Current Version Date: 9/9/2009
Principal Investigator: Robert D. Timmerman, M.D.
Primary Objective:

To determine if radiotherapy involving high biological dose with limited treatment volume (using SBRT techniques) achieves acceptable local control (i.e., >= 80%) in frail patients with medically inoperable early stage non-small cell lung cancer.

Patient Population:

Patients with T1, T2 (<= 5 cm), T3 (<= 5 cm), N0, M0 medically inoperable non-small cell lung cancer; patients with T3 tumors chest wall primary tumors only; no patients with tumors of any T-stage in the zone of the proximal bronchial tree*. Patients with T3 tumors based on mediastinal invasion or < 2 cm toward carina invasion are not eligible.

Target Accrual: 52
Current Accrual: 59
Status: Terminated
Date: 12/15/2016
Participating Sites:
ACR Clinical Research Center Philadelphia PA
Arizona Oncology Services Foundation Scottsdale AZ
Carolinas Medical Center/Levine Cancer Institute Charlotte NC
Cleveland Clinic Foundation Cleveland OH
CoxHealth South Hospital Springfield MO
Froedtert and the Medical College of Wisconsin Milwaukee WI
Gulf Coast Cancer Treatment Center Panama City FL
Gundersen Lutheran Medical Center La Crosse WI
Highland Hospital Rochester NY
Illinois CancerCare-Peoria Peoria IL
Image-Guided Therapy QA Center (ITC) St. Louis MO
Indiana University/Melvin and Bren Simon Cancer Center Indianapolis IN
Kansas City CCOP Prairie Village KS
Lehigh Valley Hospital-Cedar Crest Allentown PA
Liberty Hospital Liberty MO
M D Anderson Cancer Center Houston TX
Mercy Hospital Springfield Springfield MO
Methodist Hospital Philadelphia PA
Methodist Medical Center of Illinois Peoria IL
Nebraska Methodist Hospital Omaha NE
Northeast Radiation Oncology Center Dunmore PA
OSF Saint Francis Medical Center Peoria IL
Ozark Health Ventures LLC-Cancer Research for The Ozarks Springfield Springfield MO
Radiological Physics Center (RPC) Houston TX
Richard L. Roudebush VA Medical Center Indianapolis IN
Scottsdale Radiation Oncology Centers-Osborn Center Scottsdale AZ
Scottsdale Radiation Oncology Centers-Shea Center Scottsdale AZ
Siteman Cancer Center at Saint Peters Hospital St. Peters MO
Siteman Cancer Center at West County Hospital St. Louis MO
Thomas Jefferson University Hospital Philadelphia PA
Tulane University Medical Center New Orleans LA
University Health Network-Princess Margaret Hospital Toronto, Ontario
University of Colorado Hospital Aurora CO
University of Florida Health Science Center - Gainesville Gainesville FL
University of Maryland/Greenebaum Cancer Center Baltimore MD
University of Michigan Comprehensive Cancer Center Ann Arbor MI
University of Rochester Rochester NY
University of Southwestern Moncrief Cancer Ctr-Fort Worth Fort Worth TX
University of Texas Southwestern Medical School Dallas TX
University of Wisconsin Hospital and Clinics Madison WI
UT Southwestern/Simmons Cancer Center-Dallas Dallas TX
Virginia Commonwealth University/Massey Cancer Center Richmond VA
Washington University School of Medicine St. Louis MO
Updated: 2/9/2017

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