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RTOG 0239 Protocol Information

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A Phase II Study of Accelerated High Dose Thoracic Irradiation With Concurrent Chemotherapy for Patients With Limited Small Cell Lung Cancer
Protocol Documents
Current Version Date: 3/24/2010
Principal Investigator: Ritsuko Komaki, M.D.
Primary Objective:

To determine the response rate and progression-free and overall survival in patients with limited small cell lung cancer treated with cisplatin and oral etoposide and combined with concurrent higher dose of thoracic radiotherapy (TRT) followed by etoposide and cisplatin.
To determine the qualitative and quantitative toxicity and reversibility of toxicity of daily TRT followed by hyperfractionated TRT as a boost.

Patient Population:

Histologic proof or unequivocal cytologic proof of SCLC Limited disease SCLC, clinical stages I-IIIB (AJCC, 1997), whatever the induction treatment

Target Accrual: 71
Current Accrual: 72
Status: Terminated
Date: 11/5/2013
Participating Sites:
Allegiance Health Jackson MI
Atrium Medical Center-Middletown Regional Hospital Franklin OH
Aultman Hospital Canton OH
Bay Area Tumor Institute Oakland CA
Beaumont Hospital-Dearborn Dearborn MI
Borgess Medical Center Kalamazoo MI
Bronson Methodist Hospital Kalamazoo MI
Bryn Mawr Hospital Bryn Mawr PA
Cancer Care Center, Inc Salem OH
Cancer Treatment Center Wooster OH
Cape Radiation Oncology Cape Girardeau MO
Centre Hospitalier de l`Universite de Montreal-Notre Dame Montreal Quebec
Champlain Valley Physicians Hospital Medical Center Plattsburgh NY
CHU de Quebec-L'Hotel-Dieu de Quebec (HDQ) Quebec
Cleveland Clinic Foundation Cleveland OH
Columbia Saint Mary's Water Tower Medical Commons Milwaukee WI
Community Howard Regional Health Kokomo IN
Community Medical Center Toms River NJ
Cottonwood Hospital Medical Center Murray UT
Dayton CCOP Kettering OH
Delaware County Memorial Hospital Drexel Hill PA
Dixie Medical Center Regional Cancer Center East St. George UT
East Bay Radiation Oncology Center Castro Valley CA
Elkhart General Hospital Elkhart IN
Faxton-Saint Luke's Healthcare Utica NY
Finley Hospital Dubuque IA
Franciscan Saint Francis Health-Beech Grove Beech Grove IN
Genesys Hurley Cancer Institute Flint MI
Good Samaritan Hospital - Dayton Dayton OH
Grandview Hospital Dayton OH
Greene Memorial Hospital Xenia OH
Gundersen Lutheran Medical Center La Crosse WI
Henry Ford Hospital Detroit MI
Hillcrest Hospital Cancer Center Mayfield Heights OH
Hurley Medical Center Flint MI
Indiana University/Melvin and Bren Simon Cancer Center Indianapolis IN
Inspira Medical Center Vineland Vineland NJ
IU Health La Porte Hospital La Porte IN
Johns Hopkins University/Sidney Kimmel Cancer Center Baltimore MD
Kalamazoo CCOP-West Michigan Cancer Center Kalamazoo MI
Kansas City CCOP Prairie Village KS
Kettering Medical Center Dayton OH
Lakeland Hospital St Joseph MI
Lankenau Medical Center Wynnewood PA
LDS Hospital Salt Lake City UT
Liberty Hospital Liberty MO
M D Anderson Cancer Center Houston TX
Mainline Health CCOP Wynnewood PA
McKay-Dee Hospital Center Ogden UT
Memorial University Medical Center Savannah GA
Methodist Cancer Center Omaha NE
Miami Valley Hospital Dayton OH
Michigan Cancer Research Consortium Community Clinical Oncology Program Ann Arbor MI
Northern Indiana Cancer Research Consortium South Bend IN
Northridge Hospital Medical Center Northridge CA
Paoli Memorial Hospital Paoli PA
Pomona Valley Hospital Medical Center Pomona CA
Radiation Oncology Center Alliance OH
Rapid City Regional Hospital Rapid City SD
Reading Hospital Reading PA
Richard L. Roudebush VA Medical Center Indianapolis IN
Saint Agnes Hospital Baltimore MD
Saint John Hospital and Medical Center Grosse Pointe Woods MI
Saint John Macomb-Oakland Hospital Warren MI
Saint Joseph Mercy Hospital Ann Arbor MI
Saint Joseph Regional Medical Center South Bend In
Saint Mary's of Michigan Saginaw MI
Singing River Hospital Pascagoula MS
Southeast Cancer Control Consortium CCOP Winston Salem NC
Sparrow Hospital Lansing MI
St. Francis Medical Center Trenton NJ
St. Louis University Hospital St. Louis MO
Summa Akron City Hospital/Cooper Cancer Center Akron OH
The Cancer Center for Southern Kentucky Bowling Green KY
Tom Baker Cancer Centre Calgary, Alberta
Tulane University Medical Center New Orleans LA
University of Alabama at Birmingham Cancer Center Birmingham AL
University of Cincinnati/Barrett Cancer Center Cincinnati OH
University of Colorado Hospital Aurora CO
University of Kentucky/Markey Cancer Center Lexington KY
University of Miami Miller School of Medicine-Sylvester Cancer Center Miami FL
Upper Valley Medical Center Troy OH
Utah Cancer Specialists-Salt Lake City Salt Lake City UT
Utah Valley Regional Medical Center Provo UT
Valley Medical Oncology Consultants Pleasanton CA
Vanderbilt University/Ingram Cancer Center Nashville TN
Veteran Affairs Medical Center Dayton OH
Washington University School of Medicine St. Louis MO
Wayne Memorial Hospital Goldsboro NC
Wayne Radiation Oncology Goldsboro NC
Wayne State University/Karmanos Cancer Institute Detroit MI
Wheeling Hospital/Schiffler Cancer Center Wheeling WV
Wilmed Radiation Oncology Services Wilson NC
Zablocki VA Medical Center-Wood Milwaukee WI
Updated: 11/6/2013

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