Minimize
 

RTOG 0241 Protocol Information

Minimize
Phase I Study of Irinotecan and Cisplatin in Combination With Twice Daily Thoracic Radiotherapy (45 Gy) or Once Daily Thoracic Radiotherapy (70 Gy) For Patients With Limited Stage Small Cell Lung Cancer
Protocol Documents
Current Version Date: 3/24/2010
Principal Investigator: Corey J. Langer, M.D.
Primary Objective:

To determine the maximum tolerated dose of irinotecan in combination with cisplatin and either twice daily RT (45 Gy) or single daily RT (70 Gy)

Patient Population:

Histologic or unequivocal cytologic proof (fine needle aspiration biopsy or two positive sputa) of SCLC is required.
Patients must have limited disease, clinical stage I-IIIB: confined to one hemithorax, but excluding T4 tumor based on malignant pleural effusion and N3 disease based on contralateral hilar or contralateral supraclavicular involvement.

Target Accrual: 36
Current Accrual: 36
Status: Terminated
Date: 11/5/2013
Participating Sites:
Alta Bates Summit Medical Center-Herrick Campus Berkeley CA
AtlantiCare Regional Medical Center Pomona NJ
Bay Area Tumor Institute Oakland CA
Brigham and Women's Hospital Boston MA
California Pacific Medical Center-Pacific Campus San Francisco CA
Christiana Care Health System-Christiana Hospital Newark DE
Cleveland Clinic Akron General Akron OH
Cottonwood Hospital Medical Center Murray UT
Delaware County Memorial Hospital Drexel Hill PA
Dixie Medical Center Regional Cancer Center East St. George UT
Duke University Medical Center Durham NC
East Bay Radiation Oncology Center Castro Valley CA
Einstein Medical Center Philadelphia Philadelphia PA
Finley Hospital Dubuque IA
Florida Hospital Orlando Orlando FL
Fox Chase Cancer Center Philadelphia PA
Froedtert and the Medical College of Wisconsin Milwaukee WI
Greenville Health System Cancer Institute-Andrews Greenville SC
Greenville Health System Cancer Institute-Eastside Greenville SC
Gundersen Lutheran Medical Center La Crosse WI
Harbin Clinic Rome GA
Holy Cross Hospital Fort Lauderdale FL
Intermountain Medical Center Murray UT
Jupiter Medical Center Jupiter FL
LDS Hospital Salt Lake City UT
M D Anderson Cancer Center Houston TX
Massachusetts General Hospital Cancer Center Boston MA
McGill University Department of Oncology Montreal
McKay-Dee Hospital Center Ogden UT
Memorial Regional Hospital/Joe DiMaggio Children's Hospital Hollywood FL
Mercy Hospital Pittsburgh PA
Methodist Hospital Philadelphia PA
Miami Cancer Institute Miami FL
Mills-Peninsula Medical Center San Mateo CA
Monmouth Medical Center Long Branch NJ
Mount Sinai Medical Center Miami Beach FL
Newark Beth Israel Medical Center Newark NJ
Northeast Radiation Oncology Center Dunmore PA
Orange Regional Medical Center Middletown NY
Palo Alto Medical Foundation Health Care Palo Alto CA
Parkridge Medical Center Chattanooga TN
Penn State University and The Milton S. Hershey Medical Ctr Hershey PA
Pocono Medical Center East Strousburg PA
Providence Saint Joseph Medical Center/Disney Family Cancer Center Burbank CA
Providence St. Joseph Medical Center - Disney Family CA Ctr Burbank CA
Roswell Park Cancer Institute Buffalo NY
Sandra L Maxwell Cancer Center Cedar City UT
State University of New York Upstate Medical University Syracuse NY
Sutter Health Western Division Cancer Research Group Novato CA
Thomas Jefferson University Hospital Philadelphia PA
University of Alabama at Birmingham Cancer Center Birmingham AL
University of Chicago Comprehensive Cancer Center Chicago IL
University of Florida Health Science Center - Gainesville Gainesville FL
University of Florida Health Science Center - Jacksonville Jacksonville FL
University of Maryland/Greenebaum Cancer Center Baltimore MD
University of Missouri - Ellis Fischel Columbia MO
University of North Carolina - Chapel Hill Chapel Hill NC
University of Texas Medical Branch Galveston TX
University of Texas Southwestern Medical School Dallas TX
University of Texas Southwestern Medical School Dallas TX
Utah Cancer Specialists-Salt Lake City Salt Lake City UT
Utah Valley Regional Medical Center Provo UT
Valley Medical Oncology Consultants Pleasanton CA
Vanderbilt University/Ingram Cancer Center Nashville TN
Virtua Memorial Mount Holly NJ
Wayne Memorial Hospital Goldsboro NC
Wayne Radiation Oncology Goldsboro NC
William Beaumont Hospital-Royal Oak Royal Oak MI
Updated: 11/6/2013

You must be logged in to view this file.

Login  |  Close

You must be logged in to view this file.

Login  |  Close