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RTOG 0324 Protocol Information

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A Phase II Study of Cetuximab (C225) In Combination with Chemoradiation in Patients with Stage IIIA/B Non-Small Cell Lung Cancer (NSCLC)
Protocol Documents
Current Version Date: 5/6/2010
Principal Investigator: George Blumenschein, M.D.
Primary Objective:

Determine the feasibility of concurrent cetuximab and chemoradiation as measured by safety and compliance. Safety is measured by the rate of grade 3 or worse nonhematological toxicities occurring prior to the beginning of consolidation therapy (including

Patient Population:

Histologically or cytologically documented NSCLC; Patients must be MO. Patients with T1-T2 with N2 or T3N1-2 are eligible, if inoperable. Patients withT4 with any N or any T with N2 or N3 disease are eligible if unresectable.

Target Accrual: 84
Current Accrual: 93
Status: Terminated
Date: 11/5/2013
Participating Sites:
Abbott-Northwestern Hospital Minneapolis MN
Abington Memorial Hospital Abington PA
Allegiance Health Jackson MI
AnMed Health Cancer Center Anderson SC
Annie Penn Memorial Hospital Reidsville NC
Arizona Oncology Services Foundation Scottsdale AZ
Arlington Cancer Center Arlington TX
Ascension Saint John Hospital Grosse Pointe Woods MI
AtlantiCare Regional Medical Center -Main Campus Pomona NJ
Aultman Health Foundation Canton OH
Baptist Cancer Institute Jacksonville FL
Baton Rouge General Medical Center Baton Rouge LA
Bay Area Tumor Institute Oakland CA
Beaumont Hospital - Dearborn Dearborn MI
Bon Secours Saint Mary's Hospital Richmond VA
Borgess Medical Center Kalamazoo MI
Bronson Methodist Hospital Kalamazoo MI
Broward Health Medical Center Fort Lauderdale FL
Broward Health North Pompano Beach FL
Bryn Mawr Hospital Bryn Mawr PA
Cape Fear Valley Health System Fayetteville NC
CaroMont Regional Medical Center Gastonia NC
Christiana Care Health System-Christiana Hospital Newark DE
Cleveland Clinic Akron General Akron OH
Cone Health Cancer Center Greensboro NC
Cottonwood Hospital Medical Center Murray UT
Covenant Medical Center-Lakeside Lubbock TX
Cox Medical Center Springfield MO
CoxHealth South Hospital Springfield MO
Dayton CCOP Kettering OH
Delaware County Memorial Hospital Drexel Hill PA
Dixie Medical Center Regional Cancer Center East St. George UT
East Bay Radiation Oncology Center Castro Valley CA
Fairview Ridges Hospital Burnsville MN
Fairview-Southdale Hospital Edina MN
Finley Hospital Dubuque IA
Genesys Hurley Cancer Institute Flint MI
Greenville Health System Cancer Institute-Andrews Greenville SC
Greenville Health System Cancer Institute-Eastside Greenville SC
Gulf Coast Cancer Treatment Center Panama City FL
Gundersen Lutheran Medical Center La Crosse WI
Hematology Oncology Associates of Central New York-East Syracuse East Syracuse NY
Hunter Holmes McGuire Veterans Administration Medical Center Richmond VA
Hurley Medical Center Flint MI
Ingalls Memorial Hospital Harvey IL
John B Amos Cancer Center Columbus GA
Kalamazoo CCOP-West Michigan Cancer Center Kalamazoo MI
Kansas City CCOP Prairie Village KS
Lake Huron Medical Center Port Huron MI
Lankenau Medical Center Wynnewood PA
LDS Hospital Salt Lake City UT
Lehigh Valley Hospital-Cedar Crest Allentown PA
Liberty Hospital Liberty MO
Louisiana State University Health Science Center New Orleans LA
M D Anderson Cancer Center Houston TX
Mainline Health CCOP Wynnewood PA
Margaret R Pardee Memorial Hospital Hendersonville NC
Mary Bird Perkins Cancer Center Baton Rouge LA
McKay-Dee Hospital Center Ogden UT
Mercy Hospital Coon Rapids MN
Mercy Hospital Springfield Springfield MO
Methodist Hospital St. Louis Park MN
Metro-Minnesota CCOP St. Louis Park MN
Michigan Cancer Research Consortium Community Clinical Oncology Program Ann Arbor MI
Minnesota Oncology Hematology PA-Maplewood Maplewood MN
Mission Hospital Inc-Memorial Campus Asheville NC
Mobile Infirmary Medical Center Mobile AL
Monmouth Medical Center Long Branch NJ
Moorehead Memorial Hospital Eden NC
Mount Sinai Hospital Chicago IL
Nebraska Methodist Hospital Omaha NE
North Memorial Medical Health Center Robbinsdale MN
Novant Health Forsyth Medical Center Winston Salem NC
Novant Health Presbyterian Medical Center Charlotte NC
Orange Regional Medical Center Middletown NY
Ozark Health Ventures LLC-Cancer Research for The Ozarks Springfield Springfield MO
Paoli Memorial Hospital Paoli PA
Penn State Milton S Hershey Medical Center Hershey PA
Piedmont Radiation Oncology Associates Greenville SC
Pocono Medical Center East Strousburg PA
Pomona Valley Hospital Medical Center Pomona CA
Providence Holy Cross Medical Center Mission Hills CA
Providence St. Joseph Medical Center - Disney Family CA Ctr Burbank CA
Randolph Hospital Ashboro NC
Rapid City Regional Hospital Rapid City SD
Ridgeview Medical Center Waconia MN
Rutherford Hospital Rutherfordton NC
Saint Alphonsus Cancer Care Center-Boise Boise ID
Saint John Macomb-Oakland Hospital Warren MI
Saint Joseph Mercy Hospital Ann Arbor MI
Saint Joseph Mercy Oakland Pontac MI
Saint Luke's University Hospital-Bethlehem Campus Bethlehem PA
Saint Mary Mercy Hospital Livonia MI
Saint Mary's of Michigan Saginaw MI
Saint Peter's University Hospital New Brunswick NJ
Scott and White Memorial Hospital Temple TX
Scottsdale Radiation Oncology Centers-Osborn Center Scottsdale AZ
Scottsdale Radiation Oncology Centers-Shea Center Scottsdale AZ
Smilow Cancer Hospital Care Center at Saint Francis Hartford CT
Southeast Cancer Control Consortium CCOP Winston Salem NC
Sparrow Hospital Lansing MI
Spartanburg Medical Center Spartanburg SC
State University of New York Downstate Medical Center Brooklyn NY
Summa Akron City Hospital/Cooper Cancer Center Akron OH
Tallahassee Memorial HealthCare Tallahassee FL
The Cancer Center for Southern Kentucky Bowling Green KY
Thomas Jefferson University Hospital Philadelphia PA
Tom Baker Cancer Centre Calgary, Alberta
Torrance Memorial Medical Center Torrance CA
Trinity Cancer Care Center Minot ND
UF Cancer Center at Orlando Health Orlando FL
United Hospital St. Paul MN
United Hospital St. Paul MN
Unity Hospital Fridley MN
University Medical Center of Princeton at Plainsboro Princeton NJ
University of Alabama at Birmingham Cancer Center Birmingham AL
University of Florida Health Science Center - Gainesville Gainesville FL
University of Florida Health Science Center - Jacksonville Jacksonville FL
University of Kentucky/Markey Cancer Center Lexington KY
University of Washington Medical Center Seattle WA
UPMC-Mercy Hospital Pittsburgh PA
Upstate Carolina CCOP Spartanburg SC
Utah Cancer Specialists-Salt Lake City Salt Lake City UT
Utah Valley Regional Medical Center Provo UT
Valley Medical Oncology Consultants Pleasanton CA
WellSpan Health-York Hospital York PA
Wheeling Hospital/Schiffler Cancer Center Wheeling WV
Yale University New Haven CT
Yale-New Haven Hospital Saint Raphael Campus New Haven CT
Updated: 11/6/2013

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