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RTOG 0330 Protocol Information

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A Pilot Phase II Study of Preoperative Radiation Therapy and Thalidomide (IND 48832; NSC 66847) for Low Grade Primary Soft Tissue Sarcoma or Preoperative MAID/Thalidomide/Radiation Therapy for High/Intermediate Grade Primary Soft Tissue Sarcoma of the Extremity or Body Wall
Protocol Documents
Current Version Date: 8/17/2011
Principal Investigator: Burton L. Eisenberg, MD
Primary Objective:

To assess treatment delivery and toxicity of combination treatment for STS utilizing thalidomide in each patient cohort. For high/intermediate grade, Cohort A, the results will be compared to RTOG 95-14.

Patient Population:

The patient must have a primary T2a or T2b (AJCC, 6th ed.) soft tissue sarcoma (STS). The sarcoma must be located on the upper extremity (including shoulder), the lower extremity (including hip), or trunk.

Target Accrual: 44
Current Accrual: 23
Status: Terminated
Date: 11/5/2013
Participating Sites:
AnMed Health Cancer Center Anderson SC
Atrium Medical Center-Middletown Regional Hospital Franklin OH
Beth Israel Deaconess Medical Center Boston MA
Brigham and Women's Hospital Boston MA
Bryn Mawr Hospital Bryn Mawr PA
Carolinas Medical Center/Levine Cancer Institute Charlotte NC
Cheshire Medical Center-Dartmouth-Hitchcock Keene Keene NH
Cleveland Clinic Foundation Cleveland OH
Cooper Health System-Voorhees Voorhees NJ
Cooper Hospital University Medical Center Camden NJ
Cottonwood Hospital Medical Center Murray UT
Cross Cancer Institute Edmonton, Alberta
Danville Regional Medical Center Danville VA
Dartmouth Hitchcock Medical Center Lebanon NH
Dayton CCOP Kettering OH
Dixie Medical Center Regional Cancer Center East St. George UT
Franciscan Saint Francis Health-Beech Grove Beech Grove IN
Froedtert and the Medical College of Wisconsin Milwaukee WI
Good Samaritan Hospital - Dayton Dayton OH
Grandview Hospital Dayton OH
Greene Memorial Hospital Xenia OH
Johns Hopkins University/Sidney Kimmel Cancer Center Baltimore MD
Kettering Medical Center Dayton OH
Lankenau Medical Center Wynnewood PA
LDS Hospital Salt Lake City UT
Lehigh Valley Hospital-Cedar Crest Allentown PA
M D Anderson Cancer Center Houston TX
Mainline Health CCOP Wynnewood PA
Massachusetts General Hospital Boston MA
Mayo Clinic Rochester MN
Mayo Clinic in Florida Jacksonville FL
McGill University Department of Oncology Montreal
McKay-Dee Hospital Center Ogden UT
Miami Valley Hospital Dayton OH
Norris Cotton Cancer Center Saint Johnsbury VT
Northwestern University Chicago IL
Novant Health Presbyterian Medical Center Charlotte NC
Paoli Memorial Hospital Paoli PA
Penn State University and The Milton S. Hershey Medical Ctr Hershey PA
Roswell Park Cancer Institute Buffalo NY
Rutherford Hospital Rutherfordton NC
Spartanburg Medical Center Spartanburg SC
Summa Akron City Hospital/Cooper Cancer Center Akron OH
The Cancer Center for Southern Kentucky Bowling Green KY
The Research Institute of the McGill University Health Centr Montreal
Tulane University Medical Center New Orleans LA
University of Alabama at Birmingham Cancer Center Birmingham AL
University of Cincinnati/Barrett Cancer Center Cincinnati OH
University of Florida Health Science Center - Gainesville Gainesville FL
University of Florida Health Science Center - Jacksonville Jacksonville FL
University of Miami Miller School of Medicine-Sylvester Cancer Center Miami FL
University of Vermont Medical Center Burlington VT
Upper Valley Medical Center Troy OH
Upstate Carolina CCOP Spartanburg SC
Utah Cancer Specialists-Salt Lake City Salt Lake City UT
Utah Valley Regional Medical Center Provo UT
Veteran Affairs Medical Center Dayton OH
Wheeling Hospital/Schiffler Cancer Center Wheeling WV
Updated: 11/6/2013

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