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RTOG 0529 Protocol Information

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A Phase II Evaluation of Dose-Painted IMRT in Combination with 5-Fluorouracil and Mitomycin-C for Reduction of Acute Morbidity in Carcinoma of the Anal Canal
Protocol Documents
Current Version Date: 8/17/2011
Principal Investigator: Lisa Kachnic, MD
Primary Objective:

To determine if the combined rate of >= grade 2 GI and GU adverse events from IMRT+ 5-FU & Mitomycin-C is decreased by at least 15% in the first 90 days following the start of treatment, as compared to the RT+ 5-FU & Mitomycin-C arm from RTOG 9811

Patient Population:

Histologically-proven, invasive primary squamous, basaloid, or cloacogenic carcinoma of the anal canal; T stage 2-4 and N0-N3 stage

Target Accrual: 59
Current Accrual: 63
Status: Terminated
Date: 12/15/2016
Participating Sites:
21st Century Oncology-Orange Park Orange Park FL
21st Century Oncology-Palatka Palatka FL
ACR Clinical Research Center Philadelphia PA
Allegiance Health Jackson MI
Aria Health Philadelphia PA
Atrium Medical Center-Middletown Regional Hospital Franklin OH
Baptist Cancer Institute Jacksonville FL
Baptist Medical Center South Jacksonville FL
Bay Area Medical Center Marinette WI
Bay Medical Center Panama City FL
Beaumont Hospital - Dearborn Dearborn MI
Blanchard Valley Hospital Findlay OH
Boca Raton Regional Hospital Boca Raton FL
Borgess Medical Center Kalamazoo MI
Boston Medical Center Boston MA
Bronson Methodist Hospital Kalamazoo MI
Bryn Mawr Hospital Bryn Mawr PA
Cancer Treatment Center Wooster OH
Centre Hospitalier de l`Universite de Montreal-Notre Dame Montreal Quebec
Cheshire Medical Center-Dartmouth-Hitchcock Keene Keene NH
Christiana Care Health System-Christiana Hospital Newark DE
CHUM - Centre Hospitalier de l'Universite de Montreal Montreal
City of Hope Comprehensive Cancer Center Duarte CA
Cleveland Clinic Akron General Akron OH
Community Cancer Center Foundation Normal IL
Cooper Health System-Voorhees Voorhees NJ
Cooper Hospital University Medical Center Camden NJ
CoxHealth South Hospital Springfield MO
Dartmouth-Hitchcock Medical Center/Norris Cotton Cancer Center Lebanon NH
Dayton CCOP Kettering OH
Delaware County Memorial Hospital Drexel Hill PA
Dixie Medical Center Regional Cancer Center East St. George UT
Einstein Medical Center Philadelphia Philadelphia PA
EvergreenHealth Medical Center Kirkland WA
Fox Chase Cancer Center Philadelphia PA
Franciscan Saint Francis Health-Beech Grove Beech Grove IN
Froedtert and the Medical College of Wisconsin Milwaukee WI
Genesys Hurley Cancer Institute Flint MI
Good Samaritan Hospital - Dayton Dayton OH
Grandview Hospital Dayton OH
Green Bay Oncology at Saint Vincent Hospital Green Bay WI
Greene Memorial Hospital Xenia OH
Harrison Medical Center Bremerton WA
Hematology Oncology Associates of Central New York-East Syracuse East Syracuse NY
Highland Hospital Rochester NY
Holy Cross Hospital Fort Lauderdale FL
Huntsman Cancer Institute/University of Utah Salt Lake City UT
Hurley Medical Center Flint MI
Illinois CancerCare-Peoria Peoria IL
Image-Guided Therapy QA Center (ITC) St. Louis MO
Indiana University Health Methodist Hospital Indianapolis IN
Inspira Medical Center Vineland Vineland NJ
Integrated Community Oncology Network-Flager Cancer Center St Augustine FL
Integrated Community Oncology Network-Florida Cancer Center Beaches Jacksonville Beach FL
Integrated Community Oncology Network-Southside Cancer Center Jacksonville FL
Intermountain Medical Center Murray UT
IU Health Central Indiana Cancer Centers Indianapolis IN
Jupiter Medical Center Jupiter FL
Kalamazoo CCOP-West Michigan Cancer Center Kalamazoo MI
Kansas City CCOP Prairie Village KS
Kettering Medical Center Dayton OH
Lake Huron Medical Center Port Huron MI
Lankenau Medical Center Wynnewood PA
LDS Hospital Salt Lake City UT
Liberty Hospital Liberty MO
Logan Regional Hospital Logan UT
London Regional Cancer Program London Ontario
Loyola University Medical Center Maywood IL
Mainline Health CCOP Wynnewood PA
Mayo Clinic Rochester MN
McKay-Dee Hospital Center Ogden UT
Mercy General Radiation Oncology Center Sacramento CA
Mercy Hospital Springfield Springfield MO
Mercy San Juan Medical Center Carmichael CA
Methodist Hospital Philadelphia PA
Methodist Medical Center of Illinois Peoria IL
Miami Cancer Institute Miami FL
Miami Valley Hospital Dayton OH
Michigan Cancer Research Consortium Community Clinical Oncology Program Ann Arbor MI
Monmouth Medical Center Long Branch NJ
Mount Sinai Medical Center Miami Beach FL
Nevada Cancer Research Foundation CCOP Las Vegas NV
New Mexico Oncology Hematology Consultants Albuquerque NM
Norris Cotton Cancer Center-North Saint Johnsbury VT
Northeast Radiation Oncology Center Dunmore PA
Northwest Community Hospital Arlington Heights IL
Northwestern University Chicago IL
Novant Health Presbyterian Medical Center Charlotte NC
OSF Saint Francis Medical Center Peoria IL
OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center Pekin IL
OSF Saint Francis Radiation Oncology at Peoria Cancer Center Peoria IL
Ozark Health Ventures LLC-Cancer Research for The Ozarks Springfield Springfield MO
Paoli Memorial Hospital Paoli PA
Penrose-Saint Francis Healthcare Colorado Springs CO
Piedmont Hospital Atlanta GA
Providence St. Joseph Medical Center - Disney Family CA Ctr Burbank CA
Radiological Associates of Sacramento Sacramento CA
Radiological Physics Center (RPC) Houston TX
Rapid City Regional Hospital Rapid City SD
Reading Hospital Reading PA
Reid Health Richmond IN
Roswell Park Cancer Institute Buffalo NY
Saint Alphonsus Cancer Care Center-Boise Boise ID
Saint Francis Hospital Federal Way WA
Saint John Hospital and Medical Center Grosse Pointe Woods MI
Saint John Macomb-Oakland Hospital Warren MI
Saint Joseph Mercy Hospital Ann Arbor MI
Saint Joseph Mercy Oakland Pontac MI
Saint Luke's University Hospital-Bethlehem Campus Bethlehem PA
Saint Mary Mercy Hospital Livonia MI
Saint Mary's of Michigan Saginaw MI
Saint Vincent Anderson Regional Hospital/Cancer Center Anderson IN
Saint Vincent Hospital Cancer Center at Saint Mary's Green Bay WI
Saint Vincent Hospital Cancer Center Green Bay Green Bay WI
Sandra L Maxwell Cancer Center Cedar City UT
Siteman Cancer Center at Saint Peters Hospital St. Peters MO
Siteman Cancer Center at West County Hospital St. Louis MO
Smilow Cancer Hospital Care Center at Saint Francis Hartford CT
Southwest VA Regional Cancer Center Norton VA
Sparrow Hospital Lansing MI
Sparta Cancer Center Sparta NJ
St Johns Hospital, Cancer Institute Springfield IL
St. Vincent Hospital and Health Care Centers, Inc. Indianapolis IN
Summa Akron City Hospital/Cooper Cancer Center Akron OH
Summa Barberton Hospital Barberton OH
Sutter Cancer Centers Radiation Oncology Services-Auburn Auburn CA
Sutter Cancer Centers Radiation Oncology Services-Cameron Park Cameron Park CA
Sutter Cancer Centers Radiation Oncology Services-Roseville Roseville CA
Sutter Cancer Centers Radiation Oncology Services-Vacaville Vacaville CA
Sutter Medical Center Sacramento Sacramento CA
Texas Cancer Center - Medical City Dallas Dallas TX
Texas Cancer Center-Sherman Sherman TX
Texas Oncology Cancer Center Sugar Land Sugarland TX
Texas Oncology Methodist Charlton Cancer Center Dallas TX
The Klabzuba Cancer Center Fort Worth TX
The Reverend Roger Patrick Dorcy Cancer Center Pueblo CO
The University of Kansas Cancer Center-South Kansas City MO
Thomas Jefferson University Hospital Philadelphia PA
Tom Baker Cancer Centre Calgary, Alberta
UH Seidman Cancer Center at Salem Regional Medical Center Salem OH
University of Cincinnati/Barrett Cancer Center Cincinnati OH
University of Colorado Hospital Aurora CO
University of Kansas Cancer Center-Overland Park Overland Park KS
University of Maryland/Greenebaum Cancer Center Baltimore MD
University of Michigan Comprehensive Cancer Center Ann Arbor MI
University of Rochester Rochester NY
University Pointe-Precision Radiotherapy West Chester OH
Upper Delaware Valley Cancer Center Milford PA
Upper Valley Medical Center Troy OH
USC / Norris Comprehensive Cancer Center Los Angeles CA
USON-Arizona Radiation Oncology Tucson AZ
USON-Williamette Valley Cancer Center Eugene OR
Utah Cancer Specialists-Salt Lake City Salt Lake City UT
Utah Valley Regional Medical Center Provo UT
Veteran Affairs Medical Center Dayton OH
Virginia Mason CCOP Seattle WA
Virginia Mason Medical Center Seattle WA
Virtua Memorial Mount Holly NJ
Virtua Voorhees Voorhees NJ
Washington University School of Medicine St. Louis MO
Wayne Memorial Hospital Goldsboro NC
Wayne Radiation Oncology Goldsboro NC
Wayne State University/Karmanos Cancer Institute Detroit MI
Wellmont Holston Valley Hospital and Medical Center Kingsport TN
Wheeling Hospital/Schiffler Cancer Center Wheeling WV
Wilmed Radiation Oncology Services Wilson NC
Updated: 12/15/2016

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