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RTOG 0912 Protocol Information

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A Randomized Phase II Study of Concurrent Intensity Modulated Radiation Therapy (IMRT), Paclitaxel and Pazopanib (NSC 737754)/Placebo, for The Treatment of Anaplastic Thyroid Cancer
Principal Investigator: Eric Sherman, MD and Nancy Lee, MD
Primary Objective:

To evaluate the safety of IMRT, paclitaxel, and pazopanib suspension

To evaluate and compare overall survival at 1 year from study registration.

Patient Population:

Pathologically (histologically or cytologically) proven diagnosis of anaplastic thyroid cancer (a diagnosis that is noted to be "consistent with anaplastic thyroid cancer" with the presence of a thyroid mass is acceptable)

The Phase II Component is open to accrual.

 

Target Accrual: 121
Current Accrual: 123
Status: Closed to Accrual
Date: 12/30/2017
Participating Sites:
Abbott-Northwestern Hospital Minneapolis MN
ACR Clinical Research Center Philadelphia PA
Arizona Oncology Associates-Deer Valley Center Phoenix AZ
Arizona Oncology Services Foundation Scottsdale AZ
Bay Area Medical Center Marinette WI
Borgess Medical Center Kalamazoo MI
Boston Medical Center MBCCOP Boston MA
Bronson Methodist Hospital Kalamazoo MI
Case Western Reserve University Cleveland OH
Christiana Care Health System-Christiana Hospital Newark DE
Christiana Care Health System-Christiana Hospital Newark DE
Cleveland Clinic Foundation Cleveland OH
Cleveland Clinic Foundation Cleveland OH
Dixie Medical Center Regional Cancer Center East St. George UT
Emory University Hospital/Winship Cancer Institute Atlanta GA
Fairview Ridges Hospital Burnsville MN
Fairview-Southdale Hospital Edina MN
Froedtert and the Medical College of Wisconsin Milwaukee WI
Froedtert and the Medical College of Wisconsin Milwaukee WI
Greater Baltimore Medical Center Baltimore MD
Greenville Health System Cancer Institute-Seneca Seneca SC
Hennepin County Medical Center Minneapolis MN
Holy Family Memorial Hospital Manitowoc WI
Image-Guided Therapy QA Center (ITC) St. Louis MO
Intermountain Medical Center Murray UT
Kalamazoo CCOP-West Michigan Cancer Center Kalamazoo MI
Lake/University Seidman Cancer Center Mentor OH
LDS Hospital Salt Lake City UT
Logan Regional Hospital Logan UT
M D Anderson Cancer Center Houston TX
M D Anderson Cancer Center Houston TX
Mary Bird Perkins Cancer Center Baton Rouge LA
Mayo Clinic Rochester MN
Mayo Clinic Rochester MN
Mayo Clinic in Florida Jacksonville FL
Mayo Clinic in Florida Jacksonville FL
McKay-Dee Hospital Center Ogden UT
Memorial Sloan Kettering Basking Ridge Basking Ridge NJ
Memorial Sloan Kettering Cancer Center New York NY
Memorial Sloan Kettering Cancer Center New York NY
Memorial Sloan Kettering Commack Commack NY
Memorial Sloan Kettering Rockville Centre Rockville Centre NY
Mercy Hospital Coon Rapids MN
Metro-Minnesota CCOP St. Louis Park MN
Minnesota Oncology Hematology PA-Maplewood Maplewood MN
Moffitt Cancer Center Tampa FL
North Memorial Medical Health Center Robbinsdale MN
Ohio State University Comprehensive Cancer Center Columbus OH
Ohio State University Medical Center Columbus OH
Parkview Hospital Randallia Fort Wayne IN
Penn State University and The Milton S. Hershey Medical Ctr Hershey PA
Regions Hospital St Paul MN
Regions Hospital St. Paul MN
Rice Memorial Hospital Willmar MN
Ridgeview Medical Center Waconia MN
Saint John's Hospital - Healtheast Maplewood MN
Saint Vincent Hospital Cancer Center at Saint Mary's Green Bay WI
Saint Vincent Hospital Cancer Center Green Bay Green Bay WI
Sandra L Maxwell Cancer Center Cedar City UT
Sentara Cancer Institute at Sentara CarePlex Hospital Hampton VA
Sentara Cancer Institute at Sentara CarePlex Hospital Hampton VA
Sentara Norfolk General Hospital Norfolk VA
Sentara Norfolk General Hospital Norfolk VA
Sentara Virginia Beach General Hospital Virginia Beach VA
Summa Akron City Hospital/Cooper Cancer Center Akron OH
Summa Barberton Hospital Barberton OH
Summa Health Center at Lake Medina Medina OH
The James Graham Brown Cancer Center at University of Louisville Louisville KY
The University of Kansas Cancer Center-North Kansas City MO
The University of Kansas Cancer Center-South Kansas City MO
Thomas Jefferson University Hospital Philadelphia PA
Thomas Jefferson University Hospital Philadelphia PA
Touro Infirmary New Orleans LA
UCSF Medical Center-Mount Zion San Francisco CA
UCSF Medical Center-Mount Zion San Francisco CA
UCSF Medical Center-Parnassus San Francisco CA
UH Seidman Cancer Center at Southwest General Middleburgh OH
United Hospital St. Paul MN
Unity Hospital Fridley MN
University of Alabama at Birmingham Cancer Center Birmingham AL
University of Cincinnati/Barrett Cancer Center Cincinnati OH
University of Cincinnati/Barrett Cancer Center Cincinnati OH
University of Kansas Cancer Center Kansas City KS
University of Kansas Cancer Center-Overland Park Overland Park KS
University of Mississippi Medical Center Jackson MS
University of North Carolina - Chapel Hill Chapel Hill NC
University of Oklahoma Health Sciences Center Oklahoma City OK
University of Oklahoma Health Sciences Center Oklahoma City OK
University of Wisconsin Hospital and Clinics Madison WI
University of Wisconsin Hospital and Clinics Madison WI
University Pointe-Precision Radiotherapy West Chester OH
UPMC Cancer Center at UPMC McKeesport McKeesport PA
UPMC Cancer Center at UPMC Northwest Seneca PA
UPMC Cancer Center-John P. Murtha Pavilion Johnstown PA
UPMC Cancer Center-Natrona Heights Natrona Heights PA
UPMC Cancer Centre at Clarion Hospital Clarion PA
UPMC Jefferson Cancer Center Pittsburgh PA
UPMC-Arnold Palmer Pavilion Greensburg PA
UPMC-Cancer Center at St. Clair Hospital Pittsburgh PA
UPMC-Heritage Valley Health System-Medical Center, (Beaver) Beaver PA
UPMC-HVHS Cancer Center (Moon) Coraopolis PA
UPMC-Jameson Memorial Hospital New Castle PA
UPMC-Magee Womens Hospital Pittsburgh PA
UPMC-Passavant Hospital Pittsburgh PA
UPMC-Presbyterian Hospital Pittsburgh PA
UPMC-Saint Margaret Pittsburgh PA
UPMC-Shadyside Hospital Pittsburgh PA
UPMC-Shadyside Hospital Pittsburgh PA
UPMC-The Washington Hospital Washington PA
UPMC-Uniontown / Robert E. Eberly Pavilion Uniontown PA
Utah Cancer Specialists-Salt Lake City Salt Lake City UT
Utah Valley Regional Medical Center Provo UT
Updated: 2/6/2017

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