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RTOG 0933 Protocol Information

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A Phase II Trial of Hippocampal Avoidance During Whole Brain Radiotherapy for Brain Metastases--RTOG CCOP Study
Principal Investigator: Minesh P. Mehta, MD
Primary Objective:

Evaluate delayed recall as assessed by the Hopkins Verbal Learning Test-Revised (HVTL-R) 4 months after hippocampal avoidance during whole-brain radiotherapy (HA-WBRT) for brain metastasis.

Patient Population:

At least one radiologically diagnosed brain metastasis associated with a histologically proven diagnosis of a non-hematopoietic malignancy other than small cell lung cancer and germ cell malignancy. Patients must be classified as RTOG RPA class I or RPA class II.

Target Accrual: 102
Current Accrual: 113
Status: Terminated
Date: 12/15/2016
Participating Sites:
21st Century Oncology-Orange Park Orange Park FL
21st Century Oncology-Palatka Palatka FL
Abington Memorial Hospital Abington PA
ACR Clinical Research Center Philadelphia PA
Adams Cancer Center Gettysburg PA
Adena Regional Medical Center Chillicothe OH
Adventist Medical Center Portland OR
Advocate Lutheran General Hospital Park Ridge IL
Arizona Center for Cancer Care-Peoria Peoria AZ
Baptist Cancer Institute Jacksonville FL
Baptist Medical Center South Jacksonville FL
Bay Area Medical Center Marinette WI
Benefis Healthcare- Sletten Cancer Institute Great Falls MT
Billings Clinic Cancer Center Billings MT
Borgess Medical Center Kalamazoo MI
Bozeman Deaconess Hospital Cancer Center Bozeman MT
Brigham and Women's Hospital Boston MA
Bronson Methodist Hospital Kalamazoo MI
Bryn Mawr Hospital Bryn Mawr PA
Case Western Reserve University Cleveland OH
Cedars-Sinai Medical Center Los Angeles CA
Cherry Tree Cancer Center Hanover PA
Christiana Care Health System-Christiana Hospital Newark DE
Clackamas Radiation Oncology Center Clackamas OR
Cleveland Clinic Cancer Center/Fairview Hospital Cleveland OH
Cleveland Clinic Cancer Center-Independence Independence OH
Cleveland Clinic Foundation Cleveland OH
Cleveland Clinic Wooster Specialty Center Wooster OH
Cleveland Clinic-Strongsville Strongsville OH
Columbus CCOP Columbus OH
Community Cancer Center Foundation Normal IL
Community Medical Center Toms River NJ
Compass Oncology Vancouver Vancouver WA
Cooper Health System-Voorhees Voorhees NJ
Cooper Hospital University Medical Center Camden NJ
Dixie Medical Center Regional Cancer Center East St. George UT
Doctors Hospital Columbus OH
Enloe Medical Center Chico CA
Fairbanks Memorial Hospital Fairbanks AK
Florida Hospital Orlando Orlando FL
Froedtert and the Medical College of Wisconsin Milwaukee WI
Genesis Healthcare System Cancer Care Center Zainesville OH
Goshen Center for Cancer Care Goshen IN
Grady Memorial Hospital Delaware OH
Grant Medical Center Columbus OH
Heartland Regional Medical Center St. Joseph MO
Henry Ford Hospital Detroit MI
Henry Ford Macomb Hospital-Clinton Township Clinton Township MI
Hillcrest Hospital Cancer Center Mayfield Heights OH
Huntsman Cancer Institute/University of Utah Salt Lake City UT
Huron Valley Hospital Commerce Township MI
Illinois CancerCare-Peoria Peoria IL
Image-Guided Therapy QA Center (ITC) St. Louis MO
Indiana University Health Methodist Hospital Indianapolis IN
Indiana University/Melvin and Bren Simon Cancer Center Indianapolis IN
Integrated Community Oncology Network-Flager Cancer Center St Augustine FL
Integrated Community Oncology Network-Florida Cancer Center Beaches Jacksonville Beach FL
Integrated Community Oncology Network-Southside Cancer Center Jacksonville FL
Intermountain Medical Center Murray UT
IU Health Central Indiana Cancer Centers Indianapolis IN
IU Health West Hospital Avon IN
John B Amos Cancer Center Columbus GA
Juravinski Cancer Centre at Hamilton Health Sciences Hamilton, Ontario
Kalamazoo CCOP-West Michigan Cancer Center Kalamazoo MI
Kansas City CCOP Prairie Village KS
Kantonsspital Aarau Aarau
Langlade Hospital Cancer Center Antigo WI
Lankenau Medical Center Wynnewood PA
LDS Hospital Salt Lake City UT
Liberty Hospital Liberty MO
Liberty Radiation Oncology Center Liberty MO
Licking Memorial Hospital Newark OH
Logan Regional Hospital Logan UT
London Regional Cancer Program London Ontario
Los Angeles County-USC Medical Center Los Angeles CA
M D Anderson Cancer Center Houston TX
Mainline Health CCOP Wynnewood PA
Marietta Memorial Hospital Marietta OH
Mass General/ North Shore Cancer Center Danvers MA
Mayo Clinic Rochester MN
Mayo Clinic Hospital Phoenix AZ
Mayo Clinic in Arizona Scottsdale AZ
Mayo Clinic in Florida Jacksonville FL
McGill University Department of Oncology Montreal
McKay-Dee Hospital Center Ogden UT
McLaren Cancer Institute-Flint Flint MI
Memorial Hermann Memorial City Medical Center Houston TX
Menorah Medical Center Overland Park KS
Mercy General Radiation Oncology Center Sacramento CA
Mercy San Juan Medical Center Carmichael CA
Methodist Medical Center of Illinois Peoria IL
Miami Cancer Institute Miami FL
Montana Cancer Consortium CCOP Billings MT
Montefiore Medical Center - Moses Campus Bronx NY
Mount Carmel Health Center West Columbus OH
Nevada Cancer Research Foundation CCOP Las Vegas NV
New York Oncology Hematology PC - Albany Albany NY
North Kansas City Hospital North Kansas City MO
Northeast Georgia Medical Center-Gainesville Gainesville GA
Northeast Radiation Oncology Center Dunmore PA
Northside Hospital Atlanta GA
Northside Hospital-Forsyth Cumming GA
Northwestern University Chicago IL
Novant Health Forsyth Medical Center Winston Salem NC
Ohio State University Comprehensive Cancer Center Columbus OH
OSF Saint Francis Medical Center Peoria IL
OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center Pekin IL
OSF Saint Francis Radiation Oncology at Peoria Cancer Center Peoria IL
Paoli Memorial Hospital Paoli PA
Parkview Hospital Randallia Fort Wayne IN
PeaceHealth Southwest Medical Center Vancouver WA
Peninsula Regional Medical Center Salisbury MD
Penn State Milton S Hershey Medical Center Hershey PA
Penrose-Saint Francis Healthcare Colorado Springs CO
Piedmont Fayette Hospital Fayetteville GA
Piedmont Hospital Atlanta GA
Providence Hospital Mobile AL
Providence Milwaukie Hospital Milwaukie OR
Providence Portland Medical Center Portland OR
Providence Saint Vincent Medical Center Portland OR
Queen's Medical Center Honolulu HI
Radiation Oncology Associates Reno NV
Radiation Oncology Associates PC Fort Wayne IN
Radiological Associates of Sacramento Sacramento CA
Rapid City Regional Hospital Rapid City SD
Research Medical Center Kansas City MO
Riverside Methodist Hospital Columbus OH
Rocky Mountain Oncology Casper WY
Rush University Medical Center Chicago IL
Saint Ann's Hospital Westerville OH
Saint Barnabas Medical Center Livingston NJ
Saint Francis Hospital Federal Way WA
Saint Luke's Hospital of Kansas City Kansas City MO
Saint Mary's Regional Medical Center Reno NV
Saint Vincent Hospital Cancer Center at Saint Mary's Green Bay WI
Saint Vincent Hospital Cancer Center Green Bay Green Bay WI
Samuel S. Stratton VA Medical Center Albany NY
Sandra L Maxwell Cancer Center Cedar City UT
Saskatoon Cancer Centre Saskatoon, Saskatchew
Siteman Cancer Center at Saint Peters Hospital St. Peters MO
Siteman Cancer Center at West County Hospital St. Louis MO
Southern Ohio Medical Center Portsmouth OH
Southwest General Health Center Ireland Cancer Center Middleburgh OH
Spartanburg Medical Center Spartanburg SC
Springfield Regional Medical Center Springfield OH
Stony Brook University Medical Center Stony Brook NY
Summa Akron City Hospital/Cooper Cancer Center Akron OH
Sutter Cancer Centers Radiation Oncology Services-Auburn Auburn CA
Sutter Cancer Centers Radiation Oncology Services-Cameron Park Cameron Park CA
Sutter Cancer Centers Radiation Oncology Services-Roseville Roseville CA
Sutter Cancer Centers Radiation Oncology Services-Vacaville Vacaville CA
Tel Aviv Sourasky Medical Center Tel-Aviv
Texas Cancer Center-Sherman Sherman TX
Texas Oncology Bedford Bedford TX
Texas Oncology Cancer Center Sugar Land Sugarland TX
Texas Oncology-Denton South Denton TX
Texas Oncology-Wichita Falls Texoma Cancer Center Wichita Falls TX
The Cancer Center of Hawaii-Liliha Honolulu HI
The Cancer Center of Hawaii-Pali Momi Ewa Beach HI
The Kirklin Clinic at Acton Road Birmingham AL
The Klabzuba Cancer Center Fort Worth TX
The Mark H Zangmeister Center Cols OH
The Regional Cancer Center Erie PA
Thomas Jefferson University Hospital Philadelphia PA
U.W. Cancer Center - Riverview Wisconsin Rapids WI
UNC Lineberger Comprehensive Cancer Center Chapel Hill NC
University Health Network-Princess Margaret Hospital Toronto, Ontario
University of Alabama at Birmingham Cancer Center Birmingham AL
University of Arizona Medical Center-University Campus Tucson AZ
University of California Davis Comprehensive Cancer Center Sacramento CA
University of Chicago Comprehensive Cancer Center Chicago IL
University of Cincinnati/Barrett Cancer Center Cincinnati OH
University of Florida Health Science Center - Gainesville Gainesville FL
University of Hawaii Cancer Center Honolulu HI
University of Maryland/Greenebaum Cancer Center Baltimore MD
University of Miami Miller School of Medicine-Sylvester Cancer Center Miami FL
University of Nebraska Medical Center Omaha NE
University of Oklahoma Health Sciences Center Oklahoma City OK
University of Rochester Rochester NY
University of Texas Medical Branch Galveston TX
University of Virginia Cancer Center Charlottesville VA
University of Wisconsin Hospital and Clinics Madison WI
University Pointe-Precision Radiotherapy West Chester OH
UPMC-Magee Womens Hospital Pittsburgh PA
UPMC-Shadyside Hospital Pittsburgh PA
Upstate Carolina CCOP Spartanburg SC
USC / Norris Comprehensive Cancer Center Los Angeles CA
USON- Cancer Care Centers of South Texas-NE San Antonio TX
USON-Arizona Radiation Oncology Tucson AZ
USON-Cancer Care Northwest - Spokane Spokane WA
USON-Williamette Valley Cancer Center Eugene OR
Utah Cancer Specialists-Salt Lake City Salt Lake City UT
Utah Valley Regional Medical Center Provo UT
Veterans Administration Long Beach Medical Center Long Beach CA
Virginia Commonwealth University/Massey Cancer Center Richmond VA
Virginia Mason CCOP Seattle WA
Virginia Mason Medical Center Seattle WA
Virtua Memorial Mount Holly NJ
Virtua Voorhees Voorhees NJ
Washington University School of Medicine St. Louis MO
Wausau Hospital Center Wausau WI
Wayne State University/Karmanos Cancer Institute Detroit MI
Welch Cancer Center Sheridan WY
WellSpan Health-York Hospital York PA
West Texas Cancer Center Odessa TX
Western Oncology Research Consortium Portland OR
Wheaton Franciscan Cancer Care-All Saints Racine WI
William Beaumont Hospital-Royal Oak Royal Oak MI
Updated: 12/15/2016

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