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RTOG 1205 Protocol Information

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Randomized Phase II Trial of Concurrent Bevacizumab and Re-Irradiation Versus Bevacizumab Alone as Treatment for Recurrent Glioblastoma
Protocol Documents
Current Version Date: 10/3/2016
Principal Investigator: Christina Tsien, MD
Primary Objective:

To establish an improvement in overall survival in recurrent GBM patients receiving bevacizumab and re-irradiation compared with patients receiving bevacizumab alone.

Patient Population:

Patients with recurrent glioblastoma or variant (gliosarcoma or giant cell glioblastoma etc).

 

Target Accrual: 178
Current Accrual: 182
Status: Closed to Accrual
Date: 4/28/2016
Participating Sites:
21st Century Oncology-Orange Park Orange Park FL
21st Century Oncology-Palatka Palatka FL
Abbott-Northwestern Hospital Minneapolis MN
Abington Memorial Hospital Abington PA
Adena Regional Medical Center Chillicothe OH
Akron General Medical Center Akron OH
Akron General Medical Center Akron OH
Allan Blair Cancer Centre Regina, SK
Allegheny General Hospital Pittsburgh PA
Allegheny General Hospital Pittsburgh PA
Alta Bates Hospital Comprehensive Cancer Center Berkeley CA
Alta Bates Summit Medical Center - Summit Campus Oakland CA
AnMed Health Cancer Center Anderson SC
Annie Penn Memorial Hospital Reidsville NC
Aria Health Philadelphia PA
Aria Health-Torresdale Campus Philadelphia PA
Arizona Oncology Associates-Deer Valley Center Phoenix AZ
Arizona Oncology Services Foundation Scottsdale AZ
Baptist Cancer Institute Jacksonville FL
Baptist Health Lexington Lexington KY
Baptist Medical Center South Jacksonville FL
Bay Area Medical Center Marinette WI
Bay Area Tumor Institute Oakland CA
Beaumont Hospital-Dearborn Dearborn MI
Benefis Healthcare- Sletten Cancer Institute Great Falls MT
Billings Clinic Cancer Center Billings MT
Billings Clinic Cancer Center Billings MT
Borgess Medical Center Kalamazoo MI
Bronson Methodist Hospital Kalamazoo MI
California Pacific Medical Center-Pacific Campus San Francisco CA
Cape Radiation Oncology Cape Girardeau MO
Carolinas Medical Center/Levine Cancer Institute Charlotte NC
Case Western Reserve University Cleveland OH
Case Western Reserve University Cleveland OH
Christiana Care Health System-Christiana Hospital Newark DE
Clackamas Radiation Oncology Center Clackamas OR
Columbus CCOP Columbus OH
Community Cancer Center East Indianapolis IN
Community Cancer Center North Indianapolis IN
Compass Oncology Vancouver Vancouver WA
Comprehensive Cancer Centers of Nevada Las Vegas NV
Cone Health Cancer Center Greensboro NC
Cone Health Cancer Center Greensboro NC
Covenant Medical Center-Lakeside Lubbock TX
CoxHealth South Hospital Springfield MO
Delaware County Memorial Hospital Drexel Hill PA
Delbert Day Cancer Institute at PCRMC Rolla MO
Delbert Day Cancer Institute at PCRMC Rolla MO
Doctors Hospital Columbus OH
Doctors Medical Center- JC Robinson Regional Cancer Center San Pablo CA
East Bay Radiation Oncology Center Castro Valley CA
Edward Hospital/Cancer Center Naperville IL
Elkhart General Hospital Elkhart IN
Emory University Hospital/Winship Cancer Institute Atlanta GA
Emory University Hospital/Winship Cancer Institute Atlanta GA
Epic Care Pleasant Hill - Partners in Cancer Care Pleasant Hill CA
Epic Care-Dublin Dublin CA
Epic Care-Dublin Dublin CA
Fairview Ridges Hospital Burnsville MN
Fairview-Southdale Hospital Edina MN
Florida Hospital Orlando Orlando FL
Geisinger Medical Center Danville PA
Geisinger Wyoming Valley/Henry Cancer Center Wilkes Barre PA
Genesis Healthcare System Cancer Care Center Zainesville OH
Genesys Hurley Cancer Institute Flint MI
Gibbs Cancer Center-Pelham Greer SC
Grady Memorial Hospital Delaware OH
Grant Medical Center Columbus OH
Green Bay Oncology at Saint Vincent Hospital Green Bay WI
Greenville Health System Cancer Institute-Eastside Greenville SC
Greenville Health System Cancer Institute-Faris Greenville SC
Gundersen Lutheran Medical Center La Crosse WI
Hennepin County Medical Center Minneapolis MN
Highland Hospital Rochester NY
Holy Family Memorial Hospital Manitowoc WI
Hurley Medical Center Flint MI
Indiana University Health Methodist Hospital Indianapolis IN
Indiana University/Melvin and Bren Simon Cancer Center Indianapolis IN
Inova Fairfax Hospital Falls Church VA
Integrated Community Oncology Network-Flager Cancer Center St Augustine FL
Integrated Community Oncology Network-Florida Cancer Center Beaches Jacksonville Beach FL
Integrated Community Oncology Network-Southside Cancer Center Jacksonville FL
IU Health Central Indiana Cancer Centers Indianapolis IN
IU Health La Porte Hospital La Porte IN
IU Health University West Avon IN
John H Stroger Jr Hospital of Cook County Chicago IL
John Muir Medical Center-Concord Concord CA
John Muir Medical Center-Walnut Creek Concord CA
Kaiser Permanente Cancer Treatment Center South San Francisco CA
Kaiser Permanente Los Angeles Medical Center Los Angeles CA
Kaiser Permanente Los Angeles Medical Center Los Angeles CA
Kaiser Permanente Medical Center - Santa Clara Santa Clara CA
Kaiser Permanente Oakland-Broadway Oakland CA
Kalamazoo CCOP-West Michigan Cancer Center Kalamazoo MI
Kalispell Regional Medical Center Kalispell MT
Lake Huron Medical Center Port Huron MI
Lakeland Regional Health System St. Joseph MI
Lancaster General Hospital Lancaster PA
Langlade Hospital Cancer Center Antigo WI
Legacy Good Samaritan Hospital & Medical Center Portland OR
Legacy Good Samaritan Hospital and Medical Center Portland OR
Legacy Mount Hood Medical Center Gresham OR
Legacy Salmon Creek Hospital Vancouver WA
Licking Memorial Hospital Newark OH
Longmont United Hospital Longmont CO
Lowell General Hospital Lowell MA
Maine Medical Center- Scarborough Campus Portland ME
Maine Medical Center- Scarborough Campus Scarborough ME
Marietta Memorial Hospital Marietta OH
Massachusetts General Hospital Boston MA
Massachusetts General Hospital Cancer Center Boston MA
Medical University of South Carolina Charleston SC
Medical University of South Carolina Charleston SC
Memorial Hospital South Bend IN
Mercy Hospital Coon Rapids MN
Mercy Hospital Saint Louis St Louis MO
Mercy Hospital Springfield Springfield MO
Methodist Cancer Center Omaha NE
Metro-Minnesota CCOP St. Louis Park MN
Michiana Hematology Oncology PC-Mishawaka Mishawaka IN
Michigan Cancer Research Consortium Community Clinical Oncology Program Ann Arbor MI
Mills-Peninsula Medical Center San Mateo CA
Minnesota Oncology Hematology PA-Maplewood Maplewood MN
Montana Cancer Consortium CCOP Billings MT
Montefiore Medical Center - Moses Campus Bronx NY
Mount Carmel Health Center West Columbus OH
Nebraska Methodist Hospital Omaha NE
North Memorial Medical Health Center Robbinsdale MN
North Star Lodge Cancer Center at Yakima Valley Memorial Hospital Yakima WA
Northern Indiana Cancer Research Consortium South Bend IN
Northside Hospital Atlanta GA
Northside Hospital-Forsyth Cumming GA
Northwell Health/Center for Advanced Medicine Lake Success NY
Northwest Cancer Clinic Kennewich WA
Northwestern Medicine Cancer Center Warrenville Warrenville IL
Northwestern University Chicago IL
Northwestern University Chicago IL
Norton Hospital Pavilion and Medical Campus Louisville KY
Norton Hospital Pavilion and Medical Campus Louisville KY
Norton Suburban Hospital and Medical Campus Louisville KY
Novant Health Forsyth Medical Center Winston Salem NC
Novant Health Forsyth Medical Center Winston-Salem NC
Ohio State University Comprehensive Cancer Center Columbus OH
Ozark Health Ventures LLC-Cancer Research for The Ozarks Springfield Springfield MO
Parkview Hospital Randallia Fort Wayne IN
PeaceHealth Southwest Medical Center Vancouver WA
Penn State University and The Milton S. Hershey Medical Ctr Hershey PA
Piedmont Hospital Atlanta GA
Poudre Valley Hospital Fort Collins CO
ProHealth D N Greenwald Center Mukwonago WI
ProHealth Oconomowoc Memorial Hospital Oconomowoc WI
ProHealth Waukesha Memorial Hospital Waukesha WI
Providence Milwaukie Hospital Milwaukie OR
Providence Portland Medical Center Portland OR
Providence Saint Vincent Medical Center Portland OR
Providence St. Joseph Medical Center - Disney Family CA Ctr Burbank CA
Queen's Medical Center Honolulu HI
Radiation Oncology Associates PC Fort Wayne IN
Randolph Hospital Ashboro NC
Rapid City Regional Hospital Rapid City SD
Reading Hospital West Reading PA
Reading Hospital Reading PA
Regions Hospital St. Paul MN
Research Medical Center Kansas City MO
Rice Memorial Hospital Willmar MN
Ridgeview Medical Center Waconia MN
Riverside Methodist Hospital Columbus OH
Riverside Methodist Hospital Columbus OH
Robinson Radiation Oncology Ravenna OH
Rocky Mountain Oncology Casper WY
Rohnert Park Cancer Center Rohnert Park CA
Rutgers New Jersey Medical School Newark NJ
Saint Agnes Hospital Baltimore MD
Saint Alphonsus Cancer Care Center-Boise Boise ID
Saint Alphonsus Cancer Care Center-Boise Boise ID
Saint Ann's Hospital Westerville OH
Saint Francis Hospital Federal Way WA
Saint Francis Medical Center Cape Girardeau MO
Saint John Hospital and Medical Center Detroit MI
Saint John Hospital and Medical Center Grosse Pointe Woods MI
Saint John Macomb-Oakland Hospital Warren MI
Saint John's Hospital - Healtheast Maplewood MN
Saint Joseph Mercy Hospital Ann Arbor MI
Saint Joseph Mercy Hospital Ann Arbor MI
Saint Joseph Mercy Oakland Pontac MI
Saint Joseph Regional Medical Center-Mishawaka Mishawaka IN
Saint Luke's University Hospital-Bethlehem Campus Bethlehem PA
Saint Luke's University Hospital-Bethlehem Campus Bethlehem PA
Saint Mary Mercy Hospital Livonia MI
Saint Mary's of Michigan Saginaw MI
Saint Mary's Regional Medical Center Reno NV
Saint Vincent Hospital Cancer Center at Saint Mary's Green Bay WI
Saint Vincent Hospital Cancer Center at Sturgeon Bay Sturgeon Bay WI
Saint Vincent Hospital Cancer Center at Sturgeon Bay Sturgeon Bay WI
Saint Vincent Hospital Cancer Center Green Bay Green Bay WI
Saint Vincent's Medical Center Bridgeport CT
Sanford USD Medical Center - Sioux Falls Sioux Falls SD
SCL Health Lutheran Medical Center Wheat Ridge CO
Seattle Cancer Care Alliance Seattle WA
Sentara Norfolk General Hospital Norfolk VA
Sentara Virginia Beach General Hospital Virginia Beach VA
Singing River Hospital Pascagoula MS
Siteman Cancer Center at Saint Peters Hospital St. Peters MO
Siteman Cancer Center at West County Hospital St. Louis MO
Skagit Valley Hospital Mount Vernon WA
Smilow Cancer Hospital Care Center at Saint Francis Hartford CT
South Sacramento Cancer Center Sacramento CA
Southern Ohio Medical Center Portsmouth OH
Southwest VA Regional Cancer Center Norton VA
Sparrow Hospital Lansing MI
Spartanburg Medical Center Spartanburg SC
Springfield Regional Medical Center Springfield OH
Summa Akron City Hospital/Cooper Cancer Center Akron OH
Summa Akron City Hospital/Cooper Cancer Center Akron OH
Summa Barberton Hospital Barberton OH
Summa Health Center at Lake Medina Medina OH
Sutter Health Western Division Cancer Research Group Novato CA
Sutter Medical Center Sacramento Sacramento CA
Sutter Solano Medical Center Vallejo CA
Tel Aviv Sourasky Medical Center Tel Aviv
The Cancer Center of Hawaii-Liliha Honolulu HI
The Cancer Center of Hawaii-Pali Momi Ewa Beach HI
The Hospital of Central Connecticut New Britain CT
The Mark H Zangmeister Center Cols OH
The Permanente Medical Group-Roseville Radiation Oncology Roseville CA
The University of Kansas Cancer Center-Lee's Summit Lee's Summit MO
The University of Kansas Cancer Center-North Kansas City MO
The University of Kansas Cancer Center-South Kansas City MO
Thomas Jefferson University Hospital Philadelphia PA
Thomas Jefferson University Hospital Philadelphia PA
Thompson Cancer Survival Center Knoxville TN
Thompson Cancer Survival Center Knoxville TN
Tufts Medical Center Boston MA
UC San Diego Moores Cancer Center LaJolla CA
UM Sylvester Comprehensive Cancer Center at Deerfield Beach Deerfield Beach FL
United Hospital St. Paul MN
Unity Hospital Fridley MN
University of Alabama at Birmingham Cancer Center Birmingham AL
University of Alabama at Birmingham Cancer Center Birmingham AL
University of Arizona Medical Center-University Campus Tucson AZ
University of Arizona Medical Center-University Campus Tucson AZ
University of Chicago Comprehensive Cancer Center Chicago IL
University of Chicago Comprehensive Cancer Center Chicago IL
University of Colorado Hospital Aurora CO
University of Hawaii Cancer Center Honolulu HI
University of Kansas Cancer Center Kansas City KS
University of Kansas Cancer Center-Overland Park Overland Park KS
University of Kentucky/Markey Cancer Center Lexington KY
University of Kentucky/Markey Cancer Center Lexington KY
University of Maryland/Greenebaum Cancer Center Baltimore MD
University of Miami Miller School of Medicine-Sylvester Cancer Center Miami FL
University of Miami Miller School of Medicine-Sylvester Cancer Center Miami FL
University of Michigan Comprehensive Cancer Center Ann Arbor MI
University of Michigan Comprehensive Cancer Center Ann Arbor MI
University of New Mexico Cancer Center Albuquerque NM
University of Oklahoma Health Sciences Center Oklahoma City OK
University of Oklahoma Health Sciences Center Oklahoma City OK
University of Pennsylvania Medical Center Philadelphia PA
University of Rochester Rochester NY
University of Rochester Rochester NY
University of Texas Medical Branch Galveston TX
University of Texas Medical Branch Galveston TX
University of Washington Medical Center Seattle WA
University of Washington Medical Center Seattle WA
UPMC Cancer Center at UPMC McKeesport McKeesport PA
UPMC Cancer Center at UPMC Northwest Seneca PA
UPMC Cancer Center-John P. Murtha Pavilion Johnstown PA
UPMC Cancer Center-Natrona Heights Natrona Heights PA
UPMC Jefferson Cancer Center Pittsburgh PA
UPMC-Arnold Palmer Pavilion Greensburg PA
UPMC-Cancer Center at St. Clair Hospital Pittsburgh PA
UPMC-Heritage Valley Health System-Medical Center, (Beaver) Beaver PA
UPMC-Jameson Memorial Hospital New Castle PA
UPMC-Johnstown/John P. Murtha Regional Cancer Center Johnstown PA
UPMC-Passavant Hospital Pittsburgh PA
UPMC-Saint Margaret Pittsburgh PA
UPMC-Shadyside Hospital Pittsburgh PA
Upstate Carolina CCOP Spartanburg SC
UTMB Cancer Center at Victory Lakes League City TX
Valley Medical Oncology Consultants Pleasanton CA
Virginia Commonwealth University/Massey Cancer Center Richmond VA
Virginia Mason CCOP Seattle WA
Virtua Memorial Mount Holly NJ
Virtua Voorhees Voorhees NJ
Washington University School of Medicine Saint Louis MO
Washington University School of Medicine St. Louis MO
Wausau Hospital Center Wausau WI
Welch Cancer Center Sheridan WY
Wellmont Holston Valley Hospital and Medical Center Kingsport TN
Wenatchee Valley Hospital and Clinics Wenatchee WA
Western Oncology Research Consortium Portland OR
Wheeling Hospital/Schiffler Cancer Center Wheeling WV
Yale University New Haven CT
Updated: 10/17/2016

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