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RTOG 9610 Protocol Information

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Phase I/II Study of Concomitant Re-Irradiation, Hydroxyurea and 5-Fluorouracil in Patients with Recurrent Squamous Cell Cancer of the Head and Neck
Protocol Documents
Current Version Date: 9/8/1998
Principal Investigator: Richard H. Wheeler, M.D.
Primary Objective:

To identify and estimate the incidence rate of acute and late toxicities associated with combined chemotherapy and re-irradiation in patients with recurrent squamous cell cancer of the head and neck.

Patient Population:

Recurrent squamous cell cancer from a primary in the head and neck (excluding the nasopharynx and salivary gland tumors) or second primary within a previously irradiated field.
Uni- or bi-dimensionally measurable tumor confined to the head and neck with no distant metastases.

Target Accrual: 82
Current Accrual: 86
Status: Terminated
Date: 12/17/2004
Participating Sites:
21st Century Oncology Ft. Myers FL
Aultman Health Foundation Canton OH
Aurora Saint Luke's Medical Center Milwaukee WI
Bay Area Tumor Institute Oakland CA
Bayfront Cancer Care Center St. Petersburg FL
Bayshore Cancer Center Pasadena TX
Cape Cod Hospital Hyannis MA
Carle Cancer Center Urbana IL
Case Western Reserve University Cleveland OH
Central Illinois CCOP Decatur IL
Champlain Valley Physicians Hospital Medical Center Plattsburgh NY
Christiana Care Health System-Christiana Hospital Newark DE
Cleveland Clinic Akron General Akron OH
Coborn Cancer Center at Saint Cloud Hospital St. Cloud MN
Columbus CCOP Columbus OH
Community Cancer Center East Indianapolis IN
Cooper Hospital University Medical Center Camden NJ
David Grant United States Air Force Medical Center Travis AFB CA
Dayton CCOP Kettering OH
Dixie Medical Center Regional Cancer Center East St. George UT
Drexel University School of Medicine Philadelphia PA
East Jefferson General Hospital Metairie LA
Einstein Medical Center Philadelphia Philadelphia PA
Florida Oncology Center Winter Park FL
Froedtert and the Medical College of Wisconsin Milwaukee WI
Greenville Health System Cancer Institute-Eastside Greenville SC
Gulf Coast Cancer Treatment Center Panama City FL
Gundersen Lutheran Medical Center La Crosse WI
Holmes Regional Medical Center Melbourne FL
Hurley Medical Center Flint MI
Indiana University Health Methodist Hospital Indianapolis IN
Ingalls Memorial Hospital Harvey IL
Iowa Methodist Medical Center Des Moines IA
IU Health Ball Memorial Hospital Muncie IN
Jackson-Madison County General Hospital Jackson TN
Kalamazoo CCOP-West Michigan Cancer Center Kalamazoo MI
Kansas City CCOP Prairie Village KS
Laura and Isaac Perlmutter Cancer Center at NYU Langone New York NY
LDS Hospital Salt Lake City UT
Lewis and Faye Manderson Cancer Center Tuscaloosa AL
Liberty Hospital Liberty MO
Loyola University Medical Center Maywood IL
Mainline Health CCOP Wynnewood PA
Marshfield Clinic Marshfield WI
Mary Bird Perkins Cancer Center Baton Rouge LA
McGill University Department of Oncology Montreal
Medical University of South Carolina Charleston SC
Mercy Catholic Medical Center - Fitzgerald Darby PA
Mercy Regional Cancer Center Redding CA
Mesa Lutheran Hospital Mesa AZ
Methodist Medical Center of Illinois Peoria IL
MetroHealth Medical Center Cleveland OH
Miami Cancer Institute Miami FL
Missouri Valley Cancer Consortium Omaha NE
Mobile Infirmary Medical Center Mobile AL
Montefiore Medical Center - Moses Campus Bronx NY
Mount Sinai Medical Center Miami Beach FL
Nevada Cancer Research Foundation CCOP Las Vegas NV
New York-Presbyterian/Brooklyn Methodist Hospital Brooklyn NY
Ohio State University Comprehensive Cancer Center Columbus OH
Ozark Health Ventures LLC-Cancer Research for The Ozarks Springfield Springfield MO
Providence St. Joseph Medical Center - Disney Family CA Ctr Burbank CA
Radiation Oncology Associates of W. Alabama PC Tuscaloosa AL
Radiological Associates of Sacramento Sacramento CA
Regional Hospital of Scranton Scranton PA
Roswell Park Cancer Institute Buffalo NY
Saint Francis Medical Center Trenton NJ
Saint John Medical Center Tulsa OK
Saint Joseph Regional Medical Center-Mishawaka Mishawaka IN
Saint Vincent Hospital Cancer Center Green Bay Green Bay WI
Smilow Cancer Hospital Care Center at Saint Francis Hartford CT
South Georgia Medical Center/Pearlman Cancer Center Valdosta GA
Southeast Cancer Control Consortium CCOP Winston Salem NC
Southwestern Vermont Medical Center Bennington VT
St Mary Regional Cancer Center Langhorne PA
State University of New York Downstate Medical Center Brooklyn NY
Summa Akron City Hospital/Cooper Cancer Center Akron OH
Sutter Medical Center Sacramento Sacramento CA
The Christ Hospital Cincinnati OH
The James Graham Brown Cancer Center at University of Louisville Louisville KY
The Research Institute of the McGill University Health Centre (MUHC) Montreal
Thomas Jefferson University Hospital Philadelphia PA
Toledo Community Hospital Oncology Program CCOP Toledo OH
UCSF Medical Center-Mount Zion San Francisco CA
UF Cancer Center at Orlando Health Orlando FL
UNC Lineberger Comprehensive Cancer Center Chapel Hill NC
University of Alabama at Birmingham Cancer Center Birmingham AL
University of California Davis Comprehensive Cancer Center Sacramento CA
University of Colorado Hospital Aurora CO
University of Iowa/Holden Comprehensive Cancer Center Iowa City IA
University of Kentucky/Markey Cancer Center Lexington KY
University of Massachusetts Memorial Health Care Worcester MA
University of Miami Miller School of Medicine-Sylvester Cancer Center Miami FL
University of Minnesota/Masonic Cancer Center Minneapolis MN
University of Pennsylvania Medical Center Philadelphia PA
University of Pennsylvania/Abramson Cancer Center Philadelphia PA
University of Vermont Medical Center Burlington VT
Upstate Carolina CCOP Spartanburg SC
Vanderbilt University/Ingram Cancer Center Nashville TN
Virginia Commonwealth University/Massey Cancer Center Richmond VA
Virtua Memorial Mount Holly NJ
Wayne State University/Karmanos Cancer Institute Detroit MI
West Penn Hospital Pittsburgh PA
Western Oncology Research Consortium Portland OR
Wyoming Valley Health Care System - Hospital Wilkes-Barre PA
Updated: 4/8/2011

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