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RTOG 9703 Protocol Information

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A Randomized Phase II Trial of Concurrent Radiation and Chemotherapy for Advanced Squamous Cell Carcinomas of the Head and Neck
Protocol Documents
Current Version Date: 9/8/1998
Principal Investigator: Adam S. Garden, M.D.
Primary Objective:

To determine patient tolerance to each regimen

Patient Population:

 

  • Histologic proof of squamous cell carcinoma of the oral cavity, oropharynx, or hypopharynx
  • Stage III-IV disease (T3-4, N1-3, M0)
  • KPS >/= 70, >/= 18 years old
  • AGC >/= 2000, platelets >/=100,000, bilirubin </= 1.5
  • SGOT or SGPT </= 2 x upper normal, creatinine clearance >/= 50.
  • No clinically significant heart disease
  • No prior treatment to the study site
  • Patients with prior malignancy >/=5 years ago are eligible (simultaneous primaries are ineligible)
  • Signed study-specific consent form
Target Accrual: 219
Current Accrual: 241
Status: Terminated
Date: 6/30/2010
Participating Sites:
21st Century Oncology Ft. Myers FL
21st Century Oncology-Orange Park Orange Park FL
21st Century Oncology-Palatka Palatka FL
Alta Bates Summit Medical Center-Herrick Campus Berkeley CA
Anne Arundel Medical Center Annapolis MD
Arizona Oncology Services Foundation Scottsdale AZ
Aultman Health Foundation Canton OH
Baptist Cancer Institute Jacksonville FL
Baptist Cancer Institute CCOP Memphis TN
Baptist Health Madisonville/Merle Mahr Cancer Center Madisonville KY
Baptist Health Paducah Paducah KY
Baptist Hospital of East Tennessee Knoxville TN
Baptist Medical Center South Jacksonville FL
Bay Area Tumor Institute Oakland CA
Bayfront Cancer Care Center St. Petersburg FL
Bayshore Cancer Center Pasadena TX
Bixby Medical Center Adrian MI
Bridgeport Hospital Bridgeport CT
California Pacific Medical Center-Pacific Campus San Francisco CA
Cape Cod Hospital Hyannis MA
Carle Cancer Center Urbana IL
Case Western Reserve University Cleveland OH
Catawba Memorial Hospital Hickory NC
Christiana Care Health System-Christiana Hospital Newark DE
Cleveland Clinic Akron General Akron OH
Cleveland Clinic Foundation Cleveland OH
Columbia Saint Mary's Water Tower Medical Commons Milwaukee WI
Columbus CCOP Columbus OH
Community Medical Center Toms River NJ
Community Memorial Hospital Menomonee Falls WI
Cooper Hospital University Medical Center Camden NJ
Cottonwood Hospital Medical Center Murray UT
Danville Regional Medical Center Danville VA
David Grant United States Air Force Medical Center Travis AFB CA
Deaconess Medical Center Spokane WA
Dixie Medical Center Regional Cancer Center East St. George UT
East Jefferson General Hospital Metairie LA
Einstein Medical Center Philadelphia Philadelphia PA
Elliot Hospital Manchester NH
Essentia Health Cancer Center-South University Clinic Fargo ND
Finley Hospital Dubuque IA
Firelands Regional Medical Center Sandusky OH
Florida Oncology Center Winter Park FL
Fox Chase Cancer Center Philadelphia PA
Froedtert and the Medical College of Wisconsin Milwaukee WI
Genessee Hospital Rochester NY
Grand View Hospital Sellersville PA
Greater Baltimore Medical Center Baltimore MD
Gulf Coast Cancer Treatment Center Panama City FL
Gundersen Lutheran Medical Center La Crosse WI
Halifax Health Medical Center-Centers for Oncology Daytona Beach FL
Harbor Hospital Center Baltimore MD
Henry Ford Hospital Detroit MI
Holmes Regional Medical Center Melbourne FL
Holy Cross Hospital Fort Lauderdale FL
Indiana University Health Methodist Hospital Indianapolis IN
Ingalls Memorial Hospital Harvey IL
Inspira Medical Center Vineland Vineland NJ
Integrated Community Oncology Network-Flager Cancer Center St Augustine FL
Integrated Community Oncology Network-Florida Cancer Center Beaches Jacksonville Beach FL
Integrated Community Oncology Network-Southside Cancer Center Jacksonville FL
Intermountain Medical Center Murray UT
IU Health Ball Memorial Hospital Muncie IN
Jackson-Madison County General Hospital Jackson TN
John Muir Medical Center-Walnut Creek Concord CA
Johns Hopkins University/Sidney Kimmel Cancer Center Baltimore MD
Julie and Ben Rogers Cancer Institute Beaumont TX
Jupiter Medical Center Jupiter FL
Kalamazoo CCOP-West Michigan Cancer Center Kalamazoo MI
Kansas City CCOP Prairie Village KS
Laura and Isaac Perlmutter Cancer Center at NYU Langone New York NY
LDS Hospital Salt Lake City UT
Liberty Hospital Liberty MO
Lima Memorial Hospital Lima OH
Loma Linda University Medical Center Loma Linda CA
Louisiana State University Health Science Center New Orleans LA
M D Anderson Cancer Center Houston TX
M.D.Anderson Cancer Network-Tarrant County Forth Worth TX
Mainline Health CCOP Wynnewood PA
Marin General Hospital Greenbrae CA
Mary Bird Perkins Cancer Center Baton Rouge LA
McKay-Dee Hospital Center Ogden UT
Medical University of South Carolina Charleston SC
Memorial Regional Hospital/Joe DiMaggio Children's Hospital Hollywood FL
Mercy Fitzgerald Hospital Darby PA
Mercy General Radiation Oncology Center Sacramento CA
Mercy Saint Anne Hospital Toledo OH
Mercy San Juan Medical Center Carmichael CA
Mesa Lutheran Hospital Mesa AZ
Methodist Hospital Philadelphia PA
Methodist Medical Center of Illinois Peoria IL
MetroHealth Medical Center Cleveland OH
Metro-Minnesota CCOP St. Louis Park MN
Mills-Peninsula Medical Center San Mateo CA
Mobile Infirmary Medical Center Mobile AL
Moffitt Cancer Center Tampa FL
Montefiore Medical Center - Moses Campus Bronx NY
Morton Plant Hospital Clearwater FL
Mount Sinai Medical Center Miami Beach FL
Nebraska Methodist Hospital Omaha NE
Nevada Cancer Research Foundation CCOP Las Vegas NV
New York-Presbyterian/Brooklyn Methodist Hospital Brooklyn NY
North Coast Cancer Care Sandusky OH
North Star Lodge Cancer Center at Yakima Valley Memorial Hospital Yakima WA
Northern Indiana Cancer Research Consortium South Bend IN
Northwest Community Clinical Oncology Program Tacoma WA
Ochsner Medical Center Jefferson New Orleans LA
Pomona Valley Hospital Medical Center Pomona CA
ProMedica Flower Hospital Sylvania OH
Providence Alaska Medical Center Anchorage AK
Radiation Oncology Associates of W. Alabama PC Tuscaloosa AL
Radiological Associates of Sacramento Sacramento CA
Saint Agnes Medical Center Fresno CA
Saint Charles Hospital Oregon OH
Saint Francis Medical Center Trenton NJ
Saint Joseph Regional Medical Center-Mishawaka Mishawaka IN
Saint Luke's University Hospital-Bethlehem Campus Bethlehem PA
Saint Mary Medical and Regional Cancer Center Langhorne PA
Saint Vincent Hospital Cancer Center Green Bay Green Bay WI
Saint Vincent Mercy Medical Center Toledo OH
Sandra L Maxwell Cancer Center Cedar City UT
Santa Rosa Memorial Hospital Santa Rosa CA
Saskatoon Cancer Centre Saskatoon, Saskatchew
South Georgia Medical Center/Pearlman Cancer Center Valdosta GA
Southeast Cancer Control Consortium CCOP Winston Salem NC
Southern Wisconsin Radiotherapy Center Madison WI
Southwestern Vermont Medical Center Bennington VT
State University of New York Downstate Medical Center Brooklyn NY
Summa Akron City Hospital/Cooper Cancer Center Akron OH
Sutter Cancer Centers Radiation Oncology Services-Auburn Auburn CA
Sutter Cancer Centers Radiation Oncology Services-Cameron Park Cameron Park CA
Sutter Cancer Centers Radiation Oncology Services-Roseville Roseville CA
Sutter Cancer Centers Radiation Oncology Services-Vacaville Vacaville CA
Sutter Cancer Research Consortium Novato CA
Sutter Medical Center Sacramento Sacramento CA
The Cancer Center for Southern Kentucky Bowling Green KY
The Don and Sybil Harrington Cancer Center Amarillo TX
The Toledo Hospital/Toledo Children's Hospital Toledo OH
Thomas Jefferson University Hospital Philadelphia PA
Toledo Clinic Cancer Centers-Adrian Adrian MI
Toledo Clinic Cancer Centers-Maumee Maumee OH
Toledo Community Hospital Oncology Program CCOP Toledo OH
UCHealth Memorial Hospital Central Colorado Springs CO
UCSF Medical Center-Mount Zion San Francisco CA
UF Cancer Center at Orlando Health Orlando FL
University Medical Center New Orleans New Orleans LA
University of Alabama at Birmingham Cancer Center Birmingham AL
University of Chicago Comprehensive Cancer Center Chicago IL
University of Colorado Hospital Aurora CO
University of Miami Miller School of Medicine-Sylvester Cancer Center Miami FL
University of Missouri - Ellis Fischel Columbia MO
University of Toledo Toledo OH
University of Vermont Medical Center Burlington VT
Upstate Carolina CCOP Spartanburg SC
USA Health Strada Patient Care Center Mobile AL
USC / Norris Comprehensive Cancer Center Los Angeles CA
Utah Cancer Specialists-Salt Lake City Salt Lake City UT
Utah Valley Regional Medical Center Provo UT
Vassar Brothers Medical Center Poughkeepsie NY
Veterans Administration New Jersey Health Care System East Orange NJ
Virtua Memorial Mount Holly NJ
Wake Forest University Health Sciences Winston-Salem NC
Washington Cancer Institute Washington DC
Washington University School of Medicine St. Louis MO
Wayne State University/Karmanos Cancer Institute Detroit MI
West Penn Hospital Pittsburgh PA
Western Oncology Research Consortium Portland OR
Wheaton Franciscan Cancer Care-All Saints Racine WI
Wheaton Franciscan Healthcare - Saint Joseph Milwaukee WI
Wyoming Valley Health Care System - Hospital Wilkes-Barre PA
Zablocki Veterans Administration Medical Center Milwaukee WI
Updated: 4/8/2011

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