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RTOG 9813 Protocol Information

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A Phase III (Phase I Closed) Randomized Study of Radiation Therapy and Temozolomide (IND #60,265) Versus Radiation Therapy and Nitrosourea for Anaplastic Astrocytoma and Mixed Anaplastic Oligoastrocytoma (Astrocytoma Dominant)
Protocol Documents
Current Version Date: 5/30/2014
Principal Investigator: Susan M. Chang, MD
Primary Objective:

To compare overall survival.

Patient Population:

Histologically confirmed anaplastic astrocytoma by central review or mixed oligodendroglial/astrocytic tumors if the oligodroglial component is </= 25%. No prior irradiation to the head, neck, or chemotherapy for any reason.

Target Accrual: 454
Current Accrual: 230
Status: Closed to Accrual
Date:
Participating Sites:
21st Century Oncology, Inc. Ft. Myers FL
21st Century Oncology-Orange Park Orange Park FL
21st Century Oncology-Palatka Palatka FL
Abbott-Northwestern Hospital Minneapolis MN
Advocate Good Samaritan Hospital Downers Grove IL
Advocate Good Shepherd Hospital Barrington IL
Advocate Illinois Masonic Medical Center Chicago IL
Allan Blair Cancer Centre Regina, SK
Allegheny General Hospital Pittsburgh PA
Allegiance Health Jackson MI
Alta Bates Hospital Comprehensive Cancer Center Berkeley CA
AnMed Health Cancer Center Anderson SC
Anne Arundel Medical Center Annapolis MD
Arizona Oncology Associates-Deer Valley Center Phoenix AZ
Arizona Oncology Services Foundation Scottsdale AZ
Atlanta Regional CCOP Atlanta GA
Atrium Medical Center-Middletown Regional Hospital Franklin OH
Aultman Hospital Canton OH
Baptist Cancer Institute Jacksonville FL
Baptist Hospital of Miami Miami FL
Baptist Medical Center South Jacksonville FL
Bay Area Medical Center Marinette WI
Bay Area Tumor Institute Oakland CA
Beaumont Hospital-Dearborn Dearborn MI
Beth Israel Deaconess Medical Center Boston MA
Beth Israel Medical Center New York NY
Boca Raton Community Hospital-Lynn Regional Cancer Center Boca Raton FL
Bon Secours Saint Mary's Hospital Richmond VA
Borgess Medical Center Kalamazoo MI
Boston Medical Center MBCCOP Boston MA
Brigham and Women's Hospital Boston MA
Bronson Battle Creek Battle Creek MI
Bronson Methodist Hospital Kalamazoo MI
Bryn Mawr Hospital Bryn Mawr PA
Butterworth Hospital Grand Rapids MI
California Cancer Center CGOP Fresno CA
California Pacific Medical Center-Pacific Campus San Francisco CA
Cancer Care Center, Inc Salem OH
Cancer Institute of New Mexico Santa Fe NM
Cancer Treatment Center Wooster OH
Cape Radiation Oncology Cape Girardeau MO
Carle Cancer Center Urbana IL
Case Western Reserve University Cleveland OH
Central Illinois CCOP Decatur IL
Centre Hospitalier de l`Universite de Montreal-Notre Dame Montreal Quebec
Cheshire Medical Center-Dartmouth-Hitchcock Keene Keene NH
Christiana Care Health System-Christiana Hospital Newark DE
CHU de Quebec-L'Hotel-Dieu de Quebec (HDQ) Quebec
CHUM - Centre Hospitalier de l'Universite de Montreal Montreal
City of Hope Comprehensive Cancer Center Duarte CA
Cleveland Clinic Foundation Cleveland OH
Clifton Springs Hospital and Clinic Clifton Springs NY
Columbia Saint Mary's Water Tower Medical Commons Milwaukee WI
Community Cancer Center Foundation Normal IL
Community Memorial Hospital Menomonee Falls WI
Cottonwood Hospital Medical Center Murray UT
Covenant Medical Center-Lakeside Lubbock TX
CoxHealth South Hospital Springfield MO
Cross Cancer Institute Edmonton, Alberta
Dartmouth Hitchcock Medical Center Lebanon NH
Dayton CCOP Kettering OH
Delaware County Memorial Hospital Drexel Hill PA
Dixie Medical Center Regional Cancer Center East St. George UT
Don & Sybil Harrington Cancer Center Amarillo TX
East Bay Radiation Oncology Center Castro Valley CA
Einstein Medical Center Philadelphia Philadelphia PA
Emory University Hospital/Winship Cancer Institute Atlanta GA
Enloe Medical Center Chico CA
Erlanger Health System Chattanooga TN
Fairview Ridges Hospital Burnsville MN
Fairview-Southdale Hospital Edina MN
Finley Hospital Dubuque IA
Fox Chase Cancer Center Philadelphia PA
Franciscan Saint Francis Health-Beech Grove Beech Grove IN
Froedtert and the Medical College of Wisconsin Milwaukee WI
Froedtert Memorial Lutheran Hospital Milwaukee WI
Geisinger Medical Center Danville PA
Geisinger Wyoming Valley/Henry Cancer Center Wilkes Barre PA
Genesys Hurley Cancer Institute Flint MI
Good Samaritan Hospital - Dayton Dayton OH
Grand Rapids Clinical Oncology Program Grand Rapids MI
Grandview Hospital Dayton OH
Green Bay Oncology at Saint Vincent Hospital Green Bay WI
Green Bay Oncology Limited at Saint Mary's Hospital Green Bay WI
Greene Memorial Hospital Xenia OH
Gundersen Lutheran Medical Center La Crosse WI
Guthrie Medical Group PC-Robert Packer Hospital Sayre PA
Halifax Hospital ROC Daytona Beach FL
Henry Ford Hospital Detroit MI
Highland Hospital Rochester NY
Holy Cross Hospital Fort Lauderdale FL
Hurley Medical Center Flint MI
Illinois CancerCare-Peoria Peoria IL
Indiana University Health Ball Memorial Hospital, Inc. Muncie IN
Indiana University Health Methodist Hospital Indianapolis IN
Indiana University/Melvin and Bren Simon Cancer Center Indianapolis IN
Ingalls Memorial Hospital Harvey IL
Inspira Medical Center Vineland Vineland NJ
Integrated Community Oncology Network-Flager Cancer Center St Augustine FL
Integrated Community Oncology Network-Florida Cancer Center Beaches Jacksonville Beach FL
Integrated Community Oncology Network-Southside Cancer Center Jacksonville FL
Intermountain Medical Center Murray UT
Iowa Methodist Medical Center Des Moines IA
John B Amos Cancer Center Columbus GA
John F Kennedy Medical Center Edison NJ
John Muir Medical Center-Concord Concord CA
Johns Hopkins University/Sidney Kimmel Cancer Center Baltimore MD
Jupiter Medical Center Jupiter FL
Juravinski Cancer Centre at Hamilton Health Sciences Hamilton, Ontario
Kalamazoo CCOP-West Michigan Cancer Center Kalamazoo MI
Kansas City CCOP Prairie Village KS
Kettering Medical Center Dayton OH
Lake Huron Medical Center Port Huron MI
Lankenau Medical Center Wynnewood PA
LDS Hospital Salt Lake City UT
Legacy Emanuel Hospital & Health Center Portland OR
Legacy Good Samaritan Hospital & Medical Center Portland OR
Legacy Meridian Park Hospital Tualatin OR
Legacy Mount Hood Medical Center Gresham OR
Lehigh Valley Hospital - Muhlenberg Bethlehem PA
Lehigh Valley Hospital-Cedar Crest Allentown PA
Liberty Hospital Liberty MO
Logan Regional Hospital Logan UT
Loma Linda University Medical Center Loma Linda CA
London Regional Cancer Program London Ontario
Los Angeles County-USC Medical Center Los Angeles CA
Lovelace Medical Center-Downtown Albuquerque NM
Loyola University Medical Center Maywood IL
Lutheran General Hospital Park Ridge IL
M D Anderson Cancer Center Houston TX
Mainline Health CCOP Wynnewood PA
Marshfield Clinic Marshfield WI
Mary Bird Perkins Cancer Center Baton Rouge LA
Massachusetts General Hospital Boston MA
Mayo Clinic Rochester MN
Mayo Clinic in Arizona Scottsdale AZ
Mayo Clinic in Florida Jacksonville FL
McGill University Department of Oncology Montreal
McKay-Dee Hospital Center Ogden UT
McLaren Cancer Institute - Flint Flint MI
McLaren Northern Michigan Petoskey MI
Memorial Regional Hospital/Joe DiMaggio Children's Hospital Hollywood FL
Mercy Catholic Medical Center - Fitzgerald Darby PA
Mercy General Radiation Oncology Center Sacramento CA
Mercy Health Mercy Campus Muskegon MI
Mercy Health Saint Mary's Grand Rapids MI
Mercy Hospital Coon Rapids MN
Mercy Hospital Joplin Joplin MO
Mercy Hospital Springfield Springfield MO
Mercy San Juan Medical Center Carmichael CA
Methodist Cancer Center Omaha NE
Methodist Hospital Philadelphia PA
Methodist Medical Center of Illinois Peoria IL
Metro-Minnesota CCOP St. Louis Park MN
Miami Valley Hospital Dayton OH
Michigan Cancer Research Consortium Community Clinical Oncology Program Ann Arbor MI
Mills-Peninsula Medical Center San Mateo CA
Minnesota Oncology Hematology PA-Maplewood Maplewood MN
Mission Hospital-Memorial Campus Asheville NC
Missouri Valley Cancer Consortium Omaha NE
Mobile Infirmary Medical Center Mobile AL
Moffitt Cancer Center Tampa FL
Monmouth Medical Center Long Branch NJ
Montana Cancer Consortium CCOP Billings MT
Montefiore Medical Center - Moses Campus Bronx NY
Mount Sinai Medical Center Miami Beach FL
Munson Medical Center Traverse City MI
Natalie Warren Bryant Cancer Center at Saint Francis Tulsa OK
Nevada Cancer Research Foundation CCOP Las Vegas NV
Norris Cotton Cancer Center Saint Johnsbury VT
North Memorial Medical Health Center Robbinsdale MN
North Star Lodge Cancer Center at Yakima Valley Memorial Hospital Yakima WA
Northwest Community Clinical Oncology Program Tacoma WA
Northwest Community Hospital Arlington Heights IL
Northwestern University Chicago IL
Novant Health Forsyth Medical Center Winston Salem NC
Ochsner Medical Center Jefferson New Orleans LA
Oncology Institute of Greater Lafayette Lafayette IN
OSF Saint Francis Medical Center Peoria IL
OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center Pekin IL
OSF Saint Francis Radiation Oncology at Peoria Cancer Center Peoria IL
Ozark Health Ventures LLC-Cancer Research for The Ozarks Springfield Springfield MO
Paoli Memorial Hospital Paoli PA
PeaceHealth Saint Joseph Medical Center Bellingham WA
PeaceHealth Southwest Medical Center Vancouver WA
Penn Radiaition Oncology, Pennsylvania Hospital Philadelphia PA
Penn State University and The Milton S. Hershey Medical Ctr Hershey PA
Piedmont Hospital Atlanta GA
Pocono Medical Center East Strousburg PA
Pomona Valley Hospital Medical Center Pomona CA
Providence Alaska Medical Center Anchorage AK
Providence Milwaukie Hospital Milwaukie OR
Providence Portland Medical Center Portland OR
Providence Sacred Heart Medical Center and Children's Hospital Spokane WA
Providence Saint Vincent Medical Center Portland OR
Queen's Medical Center Honolulu HI
Radiation Oncology Associates of Albuquerque Albuquerque NM
Radiation Oncology Center Alliance OH
Radiological Associates of Sacramento Sacramento CA
Rapid City Regional Hospital Rapid City SD
Reading Hospital Reading PA
Regional Hospital of Scranton Scranton PA
Research Medical Center Kansas City MO
Ridgeview Medical Center Waconia MN
Rochester General Hospital Rochester NY
Roswell Park Cancer Institute Buffalo NY
Rush-Copley Medical Center Aurora IL
Rutherford Hospital Rutherfordton NC
Saint Alphonsus Cancer Care Center-Boise Boise ID
Saint Elizabeth Medical Center South Edgewood KY
Saint Francis Hospital Federal Way WA
Saint Francis Medical Center Cape Girardeau MO
Saint John Hospital and Medical Center Grosse Pointe Woods MI
Saint John Macomb-Oakland Hospital Warren MI
Saint Joseph Mercy Hospital Ann Arbor MI
Saint Joseph Mercy Oakland Pontac MI
Saint Mary Mercy Hospital Livonia MI
Saint Mary's of Michigan Saginaw MI
Saint Rita's Medical Center Lima OH
Saint Vincent Hospital Cancer Center Green Bay Green Bay WI
Salem Hospital Salem OR
Sandra L Maxwell Cancer Center Cedar City UT
Santa Monica Cancer Treatment Center Inglewood CA
Scott and White Memorial Hospital Temple TX
Smilow Cancer Hospital Care Center at Saint Francis Hartford CT
Southeast Cancer Control Consortium CCOP Winston Salem NC
Southwestern Vermont Medical Center Bennington VT
Sparrow Hospital Lansing MI
Spartanburg Medical Center Spartanburg SC
Spectrum Health at Butterworth Campus Grand Rapids MI
St Joseph's Hospital Medical Center Stockton CA
St Mary Regional Cancer Center Langhorne PA
St. Anthony Cancer Care Institute at St. Anthony Hospital Oklahoma City OK
St. Louis University Hospital St. Louis MO
St. Lukes Hospital Association of Duluth Duluth MN
St. Vincent Anderson Regional Hospital, Inc. Anderson IN
Stanford Cancer Institute Palo Alto Palo Alto CA
Summa Akron City Hospital/Cooper Cancer Center Akron OH
Sutter Cancer Centers Radiation Oncology Services-Auburn Auburn CA
Sutter Cancer Centers Radiation Oncology Services-Cameron Park Cameron Park CA
Sutter Cancer Centers Radiation Oncology Services-Roseville Roseville CA
Sutter Cancer Centers Radiation Oncology Services-Vacaville Vacaville CA
Sutter Health Western Division Cancer Research Group Novato CA
Swedish Covenant Hospital Chicago IL
Tel-Aviv Sourasky Medical Center Tel-Aviv
The Cancer Center of Hawaii-Liliha Honolulu HI
The Cancer Center of Hawaii-Pali Momi Ewa Beach HI
The Christ Hospital Cincinnati OH
The James Graham Brown Cancer Center at University of Louisville Louisville KY
The Ottawa Hospital Regional Cancer Centre Ottawa, Ontario
The Research Institute of the McGill University Health Centr Montreal
Thedacare Cancer Institute Appleton WI
Thomas Jefferson University Hospital Philadelphia PA
Tom Baker Cancer Centre Calgary, Alberta
Tulane University Medical Center New Orleans LA
UCHealth Memorial Hospital Central Colorado Springs CO
UCSF Medical Center-Mount Zion San Francisco CA
UF Cancer Center at Orlando Health Orlando FL
Union Hospital Terre Haute IN
United Hospital St. Paul MN
United Hospital St. Paul MN
Unity Hospital Fridley MN
University of Alabama at Birmingham Cancer Center Birmingham AL
University of California Davis Comprehensive Cancer Center Sacramento CA
University of Cincinnati/Barrett Cancer Center Cincinnati OH
University of Colorado Hospital Aurora CO
University of Florida Health Science Center - Gainesville Gainesville FL
University of Florida Health Science Center - Jacksonville Jacksonville FL
University of Hawaii Cancer Center Honolulu HI
University of Illinois Chicago IL
University of Illinois Hospital Chicago IL
University of Kansas Cancer Center Kansas City KS
University of Kentucky/Markey Cancer Center Lexington KY
University of Maryland/Greenebaum Cancer Center Baltimore MD
University of Miami Miller School of Medicine-Sylvester Cancer Center Miami FL
University of Missouri - Ellis Fischel Columbia MO
University of New Mexico Cancer Center Albuquerque NM
University of New Mexico Cancer Center Albuquerque NM
University of Rochester Rochester NY
University of South Alabama Mobile AL
University of Southern California Los Angeles CA
University of Texas Medical Branch Galveston TX
University of Utah Health Science Center Salt Lake City UT
University of Virginia Cancer Center Charlottesville VA
University of Washington Medical Center Seattle WA
University of Wisconsin Hospital and Clinics Madison WI
UP Health System Marquette Marquette MI
Upper Valley Medical Center Troy OH
Upstate Carolina CCOP Spartanburg SC
Utah Cancer Specialists-Salt Lake City Salt Lake City UT
Utah Valley Regional Medical Center Provo UT
Valley Medical Oncology Consultants Pleasanton CA
Vanderbilt University/Ingram Cancer Center Nashville TN
Veteran Affairs Medical Center Dayton OH
Virginia Commonwealth University/Massey Cancer Center Richmond VA
Virginia Mason CCOP Seattle WA
Virtua Memorial Mount Holly NJ
Wake Forest University Health Sciences Winston-Salem NC
Washington University School of Medicine St. Louis MO
Wausau Hospital Center Wausau WI
Wayne Memorial Hospital Goldsboro NC
Wayne Radiation Oncology Goldsboro NC
Wayne State University/Karmanos Cancer Institute Detroit MI
Wellmont Holston Valley Hospital and Medical Center Kingsport TN
Wenatchee Valley Hospital and Clinics Wenatchee WA
Wesley Medical Center Wichita KS
West Penn Hospital Pittsburgh PA
West Virginia University Healthcare Morgantown WV
Western Oncology Research Consortium Portland OR
Wheeling Hospital/Schiffler Cancer Center Wheeling WV
Wichita CCOP Wichita KS
William Beaumont Hospital-Royal Oak Royal Oak MI
Wilmed Radiation Oncology Services Wilson NC
Wyoming Valley Health Care System - Hospital Wilkes-Barre PA
Yale University New Haven CT
Updated: 6/9/2014

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