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RTOG 9903 Protocol Information

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A Randomized Phase III Trial to Assess the Effect of Erythropoietin on Local-Regional Control in Anemic Patients Treated with Radiotherapy for Carcinoma of the Head and Neck
Protocol Documents
Current Version Date: 8/3/2004
Principal Investigator: Mitchell Machtay, MD
Primary Objective:

The primary purpose of this trial is to test whether erythropoietin given during radiation or chemoradiation will improve the local-regional control rate in squamous cell carcinoma of the head and neck treated with definitive radiation or chemoradiation.

Patient Population:

Histologically-confirmed squamous cell carcinoma of the head and neck, including carcinoma arising from the oral cavity, oropharynx, larynx, and hypopharynx (carcinomas of the nasopharynx, nasal cavity/paranasal sinuses or salivary glands are excluded).

Target Accrual: 372
Current Accrual: 148
Status: Terminated
Date: 12/15/2016
Participating Sites:
21st Century Oncology, Inc. Ft. Myers FL
Advocate Good Samaritan Hospital Downers Grove IL
Advocate Good Shepherd Hospital Barrington IL
Advocate Illinois Masonic Medical Center Chicago IL
Allan Blair Cancer Centre Regina, SK
Alta Bates Hospital Comprehensive Cancer Center Berkeley CA
AnMed Health Cancer Center Anderson SC
Arizona Oncology Services Foundation Scottsdale AZ
AtlantiCare Regional Medical Center Pomona NJ
Aurora Saint Luke's Medical Center Milwaukee WI
Baptist Cancer Institute Jacksonville FL
Baptist Health Lexington Lexington KY
Baptist Health Madisonville/Merle Mahr Cancer Center Madisonville KY
Baptist Hospital of East Tennessee Knoxville TN
Baptist Hospital of Miami Miami FL
Baton Rouge General Medical Center Baton Rouge LA
Bay Area Tumor Institute Oakland CA
Bay Medical Center Panama City FL
Beth Israel Medical Center New York NY
Bon Secours Saint Mary's Hospital Richmond VA
California Cancer Center CGOP Fresno CA
California Pacific Medical Center-Pacific Campus San Francisco CA
Cancer Center of Santa Barbara Santa Barbara CA
Capital Health Medical Center-Hopewell Pennington NJ
Case Western Reserve University Cleveland OH
Centre Hospitalier de l`Universite de Montreal-Notre Dame Montreal Quebec
Centre Hospitalier Universitaire de Sherbrooke-Fleurimont Sherbrooke, Quebec
Champlain Valley Physicians Hospital Medical Center Plattsburgh NY
Christiana Care Health System-Christiana Hospital Newark DE
CHU de Quebec-L'Hotel-Dieu de Quebec (HDQ) Quebec
CHUM - Centre Hospitalier de l'Universite de Montreal Montreal
Clarkson Hospital Omaha NE
Clifton Springs Hospital and Clinic Clifton Springs NY
Columbia Saint Mary's Water Tower Medical Commons Milwaukee WI
Columbus Regional Hospital Columbus IN
Community Howard Regional Health Kokomo IN
Community Memorial Hospital Menomonee Falls WI
Cross Cancer Institute Edmonton, Alberta
Dartmouth Hitchcock Medical Center Lebanon NH
David Grant United States Air Force Medical Center Travis AFB CA
Dayton CCOP Kettering OH
Delaware County Memorial Hospital Drexel Hill PA
Dixie Medical Center Regional Cancer Center East St. George UT
Doctor H. Bliss Murphy Cancer Centre St. John's, NL
East Bay Radiation Oncology Center Castro Valley CA
Einstein Medical Center Philadelphia Philadelphia PA
Elliot Hospital Manchester NH
Faxton-Saint Luke's Healthcare Utica NY
Finley Hospital Dubuque IA
Fox Chase Cancer Center Philadelphia PA
Froedtert and the Medical College of Wisconsin Milwaukee WI
Glendale Memorial Hospital and Health Center Glendale CA
Greenville Health System Cancer Institute-Eastside Greenville SC
Gulf Coast Cancer Treatment Center Panama City FL
Gundersen Lutheran Medical Center La Crosse WI
Halifax Hospital ROC Daytona Beach FL
Harbor Hospital Center Baltimore MD
Health Sciences North Sudbury, Ontario
Highland Hospital Rochester NY
Holy Family Memorial Hospital Manitowoc WI
Indiana University Health Ball Memorial Hospital, Inc. Muncie IN
Indiana University Health Bloomington Bloomington IN
Indiana University Health Methodist Hospital Indianapolis IN
Indiana University/Melvin and Bren Simon Cancer Center Indianapolis IN
Inspira Medical Center Vineland Vineland NJ
John B Amos Cancer Center Columbus GA
John F Kennedy Medical Center Edison NJ
John Fitzgerald Kennedy Medical Center Lake Worth FL
Johns Hopkins University/Sidney Kimmel Cancer Center Baltimore MD
Kalamazoo CCOP-West Michigan Cancer Center Kalamazoo MI
Kansas City CCOP Prairie Village KS
Kentucky Clinic Berea Berea KY
Lake/University Seidman Cancer Center Mentor OH
Lankenau Medical Center Wynnewood PA
LDS Hospital Salt Lake City UT
Lehigh Valley Hospital-Cedar Crest Allentown PA
Lexington Clinic Cancer Center Lexington KY
Liberty Hospital Liberty MO
Louisiana State University Health Science Center New Orleans LA
Lutheran General Hospital Park Ridge IL
Maine Medical Center- Scarborough Campus Scarborough ME
Mainline Health CCOP Wynnewood PA
Mary Bird Perkins Cancer Center Baton Rouge LA
McGill University Department of Oncology Montreal
McKay-Dee Hospital Center Ogden UT
McLaren Cancer Institute - Flint Flint MI
Mercy Catholic Medical Center - Fitzgerald Darby PA
Mercy Hospital Pittsburgh PA
Methodist Cancer Center Omaha NE
Methodist Medical Center of Illinois Peoria IL
Michigan Cancer Research Consortium Community Clinical Oncology Program Ann Arbor MI
Mills-Peninsula Medical Center San Mateo CA
Mobile Infirmary Medical Center Mobile AL
Monmouth Medical Center Long Branch NJ
Montefiore Medical Center - Moses Campus Bronx NY
Mount Sinai Medical Center Miami Beach FL
Naval Medical Center - Portsmouth Portsmouth VA
Nevada Cancer Research Foundation CCOP Las Vegas NV
North Shore-LIJ Health System CCOP Manhasset NY
North Star Lodge Cancer Center at Yakima Valley Memorial Hospital Yakima WA
Northern Indiana Cancer Research Consortium South Bend IN
Northridge Hospital Medical Center Northridge CA
Northwest Community Hospital Arlington Heights IL
Northwestern Ontario Regional Cancer Centre Thunder Bay, Ontario
Northwestern University Chicago IL
Ozark Health Ventures LLC-Cancer Research for The Ozarks Springfield Springfield MO
Peninsula Regional Medical Center Salisbury MD
Pomona Valley Hospital Medical Center Pomona CA
Radiological Associates of Sacramento Sacramento CA
Rapid City Regional Hospital Rapid City SD
Regional Hospital of Scranton Scranton PA
Richard L. Roudebush VA Medical Center Indianapolis IN
Rutherford Hospital Rutherfordton NC
Saint Agnes Medical Center Fresno CA
Saint Joseph Mercy Hospital Ann Arbor MI
Saint Joseph Regional Medical Center-Mishawaka Mishawaka IN
Saint Luke's University Hospital-Bethlehem Campus Bethlehem PA
Saint Peter's University Hospital New Brunswick NJ
Saint Vincent Hospital Cancer Center Green Bay Green Bay WI
Santa Rosa Memorial Hospital CCOP Santa Rosa CA
Saskatoon Cancer Centre Saskatoon, Saskatchew
Scott and White Memorial Hospital Temple TX
Sentara Martha Jefferson Hospital Charlottesville VA
Sequoia Regional Cancer Center Visalia CA
Southeast Cancer Control Consortium CCOP Winston Salem NC
Sparrow Hospital Lansing MI
Spartanburg Medical Center Spartanburg SC
St Joseph's Hospital Medical Center Stockton CA
St. Claire Cancer Treatment Center Morehead KY
St. Vincent Anderson Regional Hospital, Inc. Anderson IN
Stanford Cancer Institute Palo Alto Palo Alto CA
State University of New York Downstate Medical Center Brooklyn NY
State University of New York Upstate Medical University Syracuse NY
Summa Akron City Hospital/Cooper Cancer Center Akron OH
Sutter Health Western Division Cancer Research Group Novato CA
The James Graham Brown Cancer Center at University of Louisville Louisville KY
The Research Institute of the McGill University Health Centr Montreal
Thomas Jefferson University Hospital Philadelphia PA
Tom Baker Cancer Centre Calgary, Alberta
Trinity Cancer Care Center Minot ND
Tulane University Medical Center New Orleans LA
UCLA Medical Center Los Angeles CA
UCSF Medical Center-Mount Zion San Francisco CA
UHHS - Chagrin Highlands Orange Village OH
UHHS-Westlake Medical Center Westlake OH
Union Hospital Terre Haute IN
University Hospital of Brooklyn at Long Island College Hospital Brooklyn NY
University Medical Center New Orleans New Orleans LA
University of California Davis Comprehensive Cancer Center Sacramento CA
University of Cincinnati/Barrett Cancer Center Cincinnati OH
University of Colorado Hospital Aurora CO
University of Florida Health Science Center - Gainesville Gainesville FL
University of Florida Health Science Center - Jacksonville Jacksonville FL
University of Kentucky/Markey Cancer Center Lexington KY
University of Maryland/Greenebaum Cancer Center Baltimore MD
University of Miami Miller School of Medicine-Sylvester Cancer Center Miami FL
University of Michigan Comprehensive Cancer Center Ann Arbor MI
University of Missouri - Ellis Fischel Columbia MO
University of Pennsylvania Medical Center Philadelphia PA
University of Pennsylvania/Abramson Cancer Center Philadelphia PA
University of Rochester Rochester NY
University of South Alabama Mobile AL
University of Southern California Los Angeles CA
University of Texas Medical Branch Galveston TX
University of Utah Health Science Center Salt Lake City UT
University of Virginia Cancer Center Charlottesville VA
University of Washington Medical Center Seattle WA
University of Wisconsin Hospital and Clinics Madison WI
University Pointe-Precision Radiotherapy West Chester OH
UPMC-Magee Womens Hospital Pittsburgh PA
UPMC-Presbyterian Hospital Pittsburgh PA
Upstate Carolina CCOP Spartanburg SC
Utah Valley Regional Medical Center Provo UT
Valley Medical Oncology Consultants Pleasanton CA
Vanderbilt University/Ingram Cancer Center Nashville TN
Veterans Administration Hospital Philadelphia PA
Veterans Administration Hospital-East Orange Campus East Orange NJ
Veterans Administration Long Beach Medical Center Long Beach CA
Veteran's Administration Medical Center - Lexington Lexington KY
Virginia Mason CCOP Seattle WA
Virtua Memorial Mount Holly NJ
Virtua Voorhees Voorhees NJ
Wake Forest University Health Sciences Winston-Salem NC
Wausau Hospital Center Wausau WI
Wayne State University/Karmanos Cancer Institute Detroit MI
West Allis Memorial Hospital West Allis WI
West Penn Hospital Pittsburgh PA
Western Oncology Research Consortium Portland OR
Wheaton Franciscan Cancer Care-All Saints Racine WI
Wheeling Hospital/Schiffler Cancer Center Wheeling WV
William Beaumont Hospital-Royal Oak Royal Oak MI
Zablocki VA Medical Center-Wood Milwaukee WI
Updated: 12/15/2016

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