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RTOG 9910 Protocol Information

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A Phase III Trial to Evaluate the Duration of Neoadjuvant Total Androgen Suppression (TAS) and Radiation Therapy (RT) in Intermediate-Risk Prostate Cancer
Protocol Documents
Current Version Date: 3/29/2010
Principal Investigator: Thomas M. Pisansky, M.D.
Primary Objective:

The primary endpoint is to compare the efficacy of moderate-duration (28-week) neoadjuvant total androgen suppression and RT with short-duration (8-week) neoadjuvant total androgen suppression and RT as related to disease-specific survival.

Patient Population:

Histologically confirmed prostate adenocarcinoma within 180 days of randomization

Zubrod performance score 0-1

Prostatic biopsy tumor grading by the Gleason Score classification

Target Accrual: 1540
Current Accrual: 1579
Status: Closed to Accrual
Date: 5/3/2004
Participating Sites:
21st Century Oncology, Inc. Ft. Myers FL
Abbott-Northwestern Hospital Minneapolis MN
Abington Memorial Hospital Abington PA
Adena Regional Medical Center Chillicothe OH
Adventist Medical Center Portland OR
Advocate Good Samaritan Hospital Downers Grove IL
Advocate Good Shepherd Hospital Barrington IL
Advocate Illinois Masonic Medical Center Chicago IL
Akron General Medical Center Akron OH
Allan Blair Cancer Centre Regina, SK
Allegiance Health Jackson MI
Alta Bates Hospital Comprehensive Cancer Center Berkeley CA
Alta Bates Summit Medical Center - Summit Campus Oakland CA
AMITA Health Adventist Medical Center LaGrange IL
Arizona Oncology Associates-Deer Valley Center Phoenix AZ
Arizona Oncology Services Foundation Scottsdale AZ
Atlanta Regional CCOP Atlanta GA
AtlantiCare Regional Medical Center Pomona NJ
Atrium Medical Center-Middletown Regional Hospital Franklin OH
Aurora Saint Luke's Medical Center Milwaukee WI
Baptist Cancer Institute Jacksonville FL
Baptist Health Madisonville/Merle Mahr Cancer Center Madisonville KY
Baptist Hospital of Miami Miami FL
Bay Area Tumor Institute Oakland CA
Bay Medical Center Panama City FL
Beaumont Hospital-Dearborn Dearborn MI
Bixby Medical Center Adrian MI
Bon Secours Saint Mary's Hospital Richmond VA
Borgess Medical Center Kalamazoo MI
Boston Medical Center MBCCOP Boston MA
Bronson Methodist Hospital Kalamazoo MI
Brooke Army Medical Center Fort Sam Houston TX
California Cancer Center CGOP Fresno CA
California Pacific Medical Center-Pacific Campus San Francisco CA
Cancer Care Center, Inc Salem OH
Cancer Treatment Center Wooster OH
Capital Health Medical Center-Hopewell Pennington NJ
Caritas Regional Cancer Center Louisville KY
Carle Cancer Center Urbana IL
Carolinas Medical Center/Levine Cancer Institute Charlotte NC
Carolinas Medical Center/Levine Cancer Institute Charlotte NC
Centre Hospitalier de l`Universite de Montreal-Notre Dame Montreal Quebec
Christiana Care Health System-Christiana Hospital Newark DE
CHUM - Centre Hospitalier de l'Universite de Montreal Montreal
Clackamas Radiation Oncology Center Clackamas OR
Clifton Springs Hospital and Clinic Clifton Springs NY
Colorado Cancer Research Program CCOP Denver CO
Columbia Saint Mary's Water Tower Medical Commons Milwaukee WI
Columbus CCOP Columbus OH
Columbus Regional Hospital Columbus IN
Community Howard Regional Health Kokomo IN
Community Memorial Hospital Menomonee Falls WI
Compass Oncology Vancouver Vancouver WA
Cottonwood Hospital Medical Center Murray UT
CoxHealth South Hospital Springfield MO
Cross Cancer Institute Edmonton, Alberta
Danville Regional Medical Center Danville VA
Dartmouth Hitchcock Medical Center Lebanon NH
David Grant United States Air Force Medical Center Travis AFB CA
Dayton CCOP Kettering OH
Deaconess Medical Center Spokane WA
Delaware County Memorial Hospital Drexel Hill PA
Dixie Medical Center Regional Cancer Center East St. George UT
Doctors Hospital Columbus OH
Doctors Medical Center- JC Robinson Regional Cancer Center San Pablo CA
East Carolina University Greenville NC
East Bay Radiation Oncology Center Castro Valley CA
Edith McNaughton Ford Center for Radiation Oncology Gross Pointe Farms MI
Einstein Medical Center Philadelphia Philadelphia PA
Elizabeth General Medical Center Elizabeth NJ
Elkhart General Hospital Elkhart IN
Epic Care Pleasant Hill - Partners in Cancer Care Pleasant Hill CA
Epic Care-Dublin Dublin CA
Fairview Ridges Hospital Burnsville MN
Fairview-Southdale Hospital Edina MN
Faxton-Saint Luke's Healthcare Utica NY
Finley Hospital Dubuque IA
Flower Hospital Toledo OH
Flower Hospital Sylvania OH
Franciscan Saint Francis Health-Beech Grove Beech Grove IN
Franciscan St. Margaret Health Hammond IN
Fresno Community Hospital Fresno CA
Froedtert and the Medical College of Wisconsin Milwaukee WI
Froedtert Memorial Lutheran Hospital Milwaukee WI
Geisinger Medical Center Danville PA
Geisinger Wyoming Valley/Henry Cancer Center Wilkes Barre PA
Genesis Healthcare System Cancer Care Center Zainesville OH
Genesys Hurley Cancer Institute Flint MI
Good Samaritan Hospital - Dayton Dayton OH
Grady Memorial Hospital Delaware OH
Grandview Hospital Dayton OH
Grant Medical Center Columbus OH
Greater Baltimore Medical Center Baltimore MD
Greater Baltimore Medical Center Baltimore MD
Greene Memorial Hospital Xenia OH
Greenville Health System Cancer Institute-Eastside Greenville SC
Gulf Coast Cancer Treatment Center Panama City FL
Gundersen Lutheran Medical Center La Crosse WI
Halifax Hospital ROC Daytona Beach FL
Harbin Clinic Rome GA
Harbor Hospital Center Baltimore MD
Health Sciences North Sudbury, Ontario
Hennepin County Medical Center Minneapolis MN
Henry Ford Hospital Detroit MI
Highland Hospital Rochester NY
Hillcrest Hospital Cancer Center Mayfield Heights OH
Holmes Regional Medical Center Melbourne FL
Holy Cross Hospital Fort Lauderdale FL
Holy Family Medical Center Des Plaines IL
Holy Family Memorial Hospital Manitowoc WI
Hunter Holmes McGuire Veterans Administration Medical Center Richmond VA
Hurley Medical Center Flint MI
Huron Valley Hospital Commerce Township MI
Indiana University Health Ball Memorial Hospital, Inc. Muncie IN
Indiana University Health Methodist Hospital Indianapolis IN
Indiana University/Melvin and Bren Simon Cancer Center Indianapolis IN
Inspira Medical Center Vineland Vineland NJ
Intermountain Medical Center Murray UT
IU Health La Porte Hospital La Porte IN
Jackson-Madison County General Hospital Jackson TN
John F Kennedy Medical Center Edison NJ
John Fitzgerald Kennedy Medical Center Lake Worth FL
John Muir Medical Center-Concord Concord CA
John Muir Medical Center-Walnut Creek Concord CA
Jupiter Medical Center Jupiter FL
Juravinski Cancer Centre at Hamilton Health Sciences Hamilton, Ontario
Kalamazoo CCOP-West Michigan Cancer Center Kalamazoo MI
Kansas City CCOP Prairie Village KS
Kettering Medical Center Dayton OH
Lake Huron Medical Center Port Huron MI
Lakeland Regional Health System St. Joseph MI
Langlade Hospital Cancer Center Antigo WI
Lankenau Medical Center Wynnewood PA
LDS Hospital Salt Lake City UT
Lehigh Valley Hospital - Muhlenberg Bethlehem PA
Lehigh Valley Hospital-Cedar Crest Allentown PA
Liberty Hospital Liberty MO
Licking Memorial Hospital Newark OH
Lima Memorial Hospital Lima OH
Logan Regional Hospital Logan UT
London Regional Cancer Program London Ontario
Long Island Jewish Medical Center Lake Success NY
Los Angeles County-USC Medical Center Los Angeles CA
Louisiana State University Health Science Center New Orleans LA
Lutheran General Hospital Park Ridge IL
Maine Medical Center- Scarborough Campus Scarborough ME
Mainline Health CCOP Wynnewood PA
Marietta Memorial Hospital Marietta OH
Marin General Hospital Greenbrae CA
Mary Bird Perkins Cancer Center Baton Rouge LA
Mass General/ North Shore Cancer Center Danvers MA
Massachusetts General Hospital Boston MA
Mayo Clinic Rochester MN
Mayo Clinic in Florida Jacksonville FL
McGill University Department of Oncology Montreal
McKay-Dee Hospital Center Ogden UT
McLaren Cancer Institute - Flint Flint MI
Medical University of Ohio Toledo OH
Memorial Hospital South Bend IN
Mercy Cancer Center Elyria OH
Mercy Catholic Medical Center - Fitzgerald Darby PA
Mercy General Radiation Oncology Center Sacramento CA
Mercy Hospital Pittsburgh PA
Mercy Hospital Coon Rapids MN
Mercy Saint Anne Hospital Toledo OH
Mercy San Juan Medical Center Carmichael CA
Methodist Cancer Center Omaha NE
Methodist Hospital Philadelphia PA
Methodist Medical Center of Illinois Peoria IL
Metro-Minnesota CCOP St. Louis Park MN
Michigan Cancer Research Consortium Community Clinical Oncology Program Ann Arbor MI
Mills-Peninsula Medical Center San Mateo CA
Minnesota Oncology Hematology PA-Maplewood Maplewood MN
Missouri Valley Cancer Consortium Omaha NE
Mobile Infirmary Medical Center Mobile AL
Moffitt Cancer Center Tampa FL
Monmouth Medical Center Long Branch NJ
Montana Cancer Consortium CCOP Billings MT
Mount Carmel Health Center West Columbus OH
Mount Sinai Hospital Chicago IL
Mount Sinai Medical Center Miami Beach FL
Natalie Warren Bryant Cancer Center at Saint Francis Tulsa OK
Naval Medical Center San Diego CA
Naval Medical Center - Portsmouth Portsmouth VA
Nevada Cancer Research Foundation CCOP Las Vegas NV
New York-Presbyterian/Brooklyn Methodist Hospital Brooklyn NY
Norris Cotton Cancer Center Saint Johnsbury VT
North Coast Cancer Care Sandusky OH
North Memorial Medical Health Center Robbinsdale MN
North Shore Radiation Oncology East Setauket NY
North Shore-LIJ Health System CCOP Manhasset NY
Northeast Radiation Oncology Center Dunmore PA
Northern Indiana Cancer Research Consortium South Bend IN
Northridge Hospital Medical Center Northridge CA
NorthShore University HealthSystem-Evanston Hospital Evanston IL
Northwest Community Clinical Oncology Program Tacoma WA
Northwest Community Hospital Arlington Heights IL
Northwestern Ontario Regional Cancer Centre Thunder Bay, Ontario
Northwestern University Chicago IL
Novant Health Forsyth Medical Center Winston Salem NC
Novant Health Presbyterian Medical Center Charlotte NC
Oncology Institute of Greater Lafayette Lafayette IN
Ozark Health Ventures LLC-Cancer Research for The Ozarks Springfield Springfield MO
Palo Alto Medical Foundation Health Care Palo Alto CA
PeaceHealth Southwest Medical Center Vancouver WA
Peninsula Regional Medical Center Salisbury MD
Penrose-Saint Francis Healthcare Colorado Springs CO
Piedmont Hospital Atlanta GA
Porter Adventist Hospital Denver CO
Princeton Radiation Oncology Center Jamesburg NJ
ProHealth D N Greenwald Center Mukwonago WI
ProHealth Oconomowoc Memorial Hospital Oconomowoc WI
ProHealth Waukesha Memorial Hospital Waukesha WI
Providence Holy Cross Medical Center Mission Hills CA
Providence Milwaukie Hospital Milwaukie OR
Providence Portland Medical Center Portland OR
Providence Saint Joseph Medical Center/Disney Family Cancer Center Burbank CA
Providence Saint Vincent Medical Center Portland OR
Providence St. Joseph Medical Center - Disney Family CA Ctr Burbank CA
QEII Health Sciences Centre/Nova Scotia Health Authority Halifax, Nova Scotia
Radiation Medical Group, Inc. San Diego CA
Radiation Oncology Associates of Albuquerque Albuquerque NM
Radiation Oncology Associates of W. Alabama PC Tuscaloosa AL
Radiation Oncology Center Alliance OH
Radiological Associates of Sacramento Sacramento CA
Rapid City Regional Hospital Rapid City SD
Reading Hospital Reading PA
Regional Hospital of Scranton Scranton PA
Regions Hospital St. Paul MN
Renown Regional Medical Center Reno NV
Rex Cancer Center Raleigh NC
Rice Memorial Hospital Willmar MN
Richard L. Roudebush VA Medical Center Indianapolis IN
Ridgeview Medical Center Waconia MN
Riverside Methodist Hospital Columbus OH
Robinson Radiation Oncology Ravenna OH
Roswell Park Cancer Institute Buffalo NY
Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital New Brunswick NJ
Saint Agnes Medical Center Fresno CA
Saint Alphonsus Cancer Care Center-Boise Boise ID
Saint Ann's Hospital Westerville OH
Saint Charles Hospital Oregon OH
Saint John Hospital and Medical Center Grosse Pointe Woods MI
Saint John Macomb-Oakland Hospital Warren MI
Saint John Medical Center Tulsa OK
Saint John Regional Hospital Saint John, NB
Saint John's Hospital - Healtheast Maplewood MN
Saint Joseph Mercy Hospital Ann Arbor MI
Saint Joseph Mercy Oakland Pontac MI
Saint Joseph Regional Medical Center-Mishawaka Mishawaka IN
Saint Luke's University Hospital-Bethlehem Campus Bethlehem PA
Saint Mary Mercy Hospital Livonia MI
Saint Mary's Hospital and Regional Medical Center Grand Junction CO
Saint Mary's of Michigan Saginaw MI
Saint Peter's University Hospital New Brunswick NJ
Saint Vincent Anderson Regional Hospital/Cancer Center Anderson IN
Saint Vincent Mercy Medical Center Toledo OH
Sandra L Maxwell Cancer Center Cedar City UT
Sanford Roger Maris Cancer Center Fargo ND
Santa Rosa Memorial Hospital CCOP Santa Rosa CA
Sarasota Radiation & Medical Oncology Center Sarasota FL
Saskatoon Cancer Centre Saskatoon, Saskatchew
SCL Health Saint Joseph Hospital Denver CO
Scott and White Memorial Hospital Temple TX
Sentara Rockingham Memorial Hospital Hahn Cancer Center Harrisonburg VA
Sequoia Regional Cancer Center Visalia CA
Siteman Cancer Center at Saint Peters Hospital St. Peters MO
Siteman Cancer Center at West County Hospital St. Louis MO
Smilow Cancer Hospital Care Center at Saint Francis Hartford CT
Southeast Cancer Control Consortium CCOP Winston Salem NC
Southern Ohio Medical Center Portsmouth OH
Southside Hospital Bayshore NY
Southwestern Vermont Medical Center Bennington VT
Sparrow Hospital Lansing MI
Spartanburg Medical Center Spartanburg SC
Springfield Regional Medical Center Springfield OH
St Anne's Hospital Fall River MA
St. Francis Medical Center Trenton NJ
Stanford Cancer Institute Palo Alto Palo Alto CA
State University of New York Downstate Medical Center Brooklyn NY
Summa Akron City Hospital/Cooper Cancer Center Akron OH
Summa Barberton Hospital Barberton OH
Sutter Cancer Centers Radiation Oncology Services-Auburn Auburn CA
Sutter Cancer Centers Radiation Oncology Services-Cameron Park Cameron Park CA
Sutter Cancer Centers Radiation Oncology Services-Roseville Roseville CA
Sutter Cancer Centers Radiation Oncology Services-Vacaville Vacaville CA
Sutter Health Western Division Cancer Research Group Novato CA
Sutter Medical Center Sacramento Sacramento CA
Sutter Solano Medical Center Vallejo CA
Tallahassee Memorial HealthCare Tallahassee FL
The Ireland Cancer Center at Community Health Partners Elyria OH
The Mark H Zangmeister Center Cols OH
The Research Institute of the McGill University Health Centr Montreal
The Toledo Hospital/Toledo Children's Hospital Toledo OH
Thomas Jefferson University Hospital Philadelphia PA
Toledo Clinic Cancer Centers-Adrian Adrian MI
Toledo Clinic Cancer Centers-Maumee Maumee OH
Toledo Community Hospital Oncology Program CCOP Toledo OH
Tom Baker Cancer Centre Calgary, Alberta
Torrance Memorial Medical Center Torrance CA
Trinity Cancer Care Center Minot ND
Tulane University Medical Center New Orleans LA
UCHealth Memorial Hospital Central Colorado Springs CO
UCLA Medical Center Los Angeles CA
UCSF Medical Center-Mount Zion San Francisco CA
UF Cancer Center at Orlando Health Orlando FL
Union Hospital Terre Haute IN
United Hospital St. Paul MN
United Hospital St. Paul MN
Unity Hospital Fridley MN
University Medical Center New Orleans New Orleans LA
University Medical Center of Princeton at Plainsboro Princeton NJ
University of Arizona Medical Center-University Campus Tucson AZ
University of California Davis Comprehensive Cancer Center Sacramento CA
University of California, San Diego Medical Center LaJolla CA
University of Colorado Hospital Aurora CO
University of Florida Health Science Center - Gainesville Gainesville FL
University of Florida Health Science Center - Jacksonville Jacksonville FL
University of Hawaii Cancer Center Honolulu HI
University of Kentucky/Markey Cancer Center Lexington KY
University of Miami Miller School of Medicine-Sylvester Cancer Center Miami FL
University of Michigan Comprehensive Cancer Center Ann Arbor MI
University of Missouri - Ellis Fischel Columbia MO
University of New Mexico Cancer Center Albuquerque NM
University of North Carolina - Chapel Hill Chapel Hill NC
University of Pennsylvania Medical Center Philadelphia PA
University of Pennsylvania/Abramson Cancer Center Philadelphia PA
University of Rochester Rochester NY
University of South Alabama Mobile AL
University of Southern California Los Angeles CA
University of Texas Medical Branch Galveston TX
University of Utah Health Science Center Salt Lake City UT
University of Wisconsin Hospital and Clinics Madison WI
Upper Valley Medical Center Troy OH
Upstate Carolina CCOP Spartanburg SC
Utah Cancer Specialists-Salt Lake City Salt Lake City UT
Utah Valley Regional Medical Center Provo UT
Valley Medical Oncology Consultants Pleasanton CA
Veteran Affairs Medical Center Dayton OH
Veteran Affairs New York Harbor Healthcare System-Brooklyn Campus Brooklyn NY
Veterans Administration Hospital Philadelphia PA
Veterans Administration Hospital-East Orange Campus East Orange NJ
Veterans Administration Long Beach Medical Center Long Beach CA
Virginia Baptist Hospital Lynchburg VA
Virginia Commonwealth University/Massey Cancer Center Richmond VA
Virginia Mason CCOP Seattle WA
Virginia Mason Medical Center Seattle WA
Virtua Memorial Mount Holly NJ
Virtua Voorhees Voorhees NJ
Wake Forest University Health Sciences Winston-Salem NC
Warren Radiation Therapy Center Warren NJ
Washington University School of Medicine St. Louis MO
Wausau Hospital Center Wausau WI
Wayne Memorial Hospital Goldsboro NC
Wayne Radiation Oncology Goldsboro NC
Wayne State University/Karmanos Cancer Institute Detroit MI
WellSpan Health-York Hospital York PA
Wesley Medical Center Wichita KS
West Allis Memorial Hospital West Allis WI
West Penn Hospital Pittsburgh PA
Western Oncology Research Consortium Portland OR
Wheaton Franciscan Cancer Care-All Saints Racine WI
Wilford Hall USAF Medical Center Lackland AFB TX
Wyoming Valley Health Care System - Hospital Wilkes-Barre PA
Yale-New Haven Hospital Saint Raphael Campus New Haven CT
Zablocki VA Medical Center-Wood Milwaukee WI
Updated: 3/11/2014

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